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Nature 413, 26-27 (6 September 2001) | doi:10.1038/35092647

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Cardiovascular biology: Platelets and proteases

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Circulating platelets are essential for the formation of blood clots. Studies of mice reveal more about the proteins involved in activating platelets, with implications for understanding strokes and heart attacks.

How do animals stop bleeding after an injury? By the time humans evolved, a common solution lay in rapidly generating a complex clot made up of blood-derived proteins (fibrin) and cells (platelets).