Table of contents
Volume 411 Number 6840 pp3-976
Naturejobs
prospectsWarming up Scandinavia p3
Paul Smaglik
doi:10.1038/35108130
Careers and Recruitment
From bench to bedside and back? p4
US academic health centres face challenges that may threaten the future vitality of the clinical research enterprise, but they are fighting back, says Diane Gershon.
Diane Gershon
doi:10.1038/35108132
From bench to bedside and back? p6
The movement of clinical trials from the public to the private sector is forcing academic health centres to re-examine their role.
Diane Gershon
doi:10.1038/35108137
Too few doctors p7
Increased demand by public healthcare for an already dwindling number of doctors has resulted in a low supply of clinical researchers in France, says Catherine Tastemain.
Catherine Tastemain
doi:10.1038/35108140
UK working for a better clinical climate p8
Helen Gavaghan
doi:10.1038/35108144
Regions
Bridging sectors Medicon Valley p10
Paul Smaglik
doi:10.1038/35108152
Opinion
Storm clouds over Brussels p871
Europe's research commissioner should develop a bolder vision for his 'European Research Area', while explicitly addressing the conflicting demands on the European Union's research programme.
doi:10.1038/35082193
Some advice for the president p871
George W. Bush needs a scientific adviser even more than the US research community needs a voice in the White House.
doi:10.1038/35082195
News
Database of molecular probes set to boost chemical genetics p873
David Adam
doi:10.1038/35082197
Asthma study death spurs inquiry p873
Paul Smaglik
doi:10.1038/35082200
Texas facilities count cost of tropical storm p874
Rex Dalton
doi:10.1038/35082202
Congress cautious on advice office p874
Matthew Davis
doi:10.1038/35082205
Japan aims to forge stronger European links p875
David Cyranoski
doi:10.1038/35082208
Stem-cell research delayed by German ethics council p875
Alison Abbott
doi:10.1038/35082211
Ruling makes it harder to convict dig thieves p876
Rex Dalton
doi:10.1038/35082214
Deputies caught on the wrong side of the law p876
Rex Dalton
doi:10.1038/35082217
Europe plans concessions to kick-start Kyoto p877
Jim Giles
doi:10.1038/35082219
Flavour switching solves riddle of missing neutrinos p877
Jim Giles
doi:10.1038/35082222
news feature
Raking through the embers p880
Clues about the origin and fate of the Universe lie hidden in the microwave radiation left over from its early days. Tom Clarke examines the latest attempts to map the Big Bang's afterglow.
Tom Clarke
doi:10.1038/35082152
The search for autism's roots p882
A marked rise in the number of people diagnosed with autism sparked controversy over the safety of certain vaccines. As the furore dies down, Kathleen Wong talks to researchers seeking the real causes of this unsettling condition.
Kathleen Wong
doi:10.1038/35082228
Correspondence
Poetry tells us that our souls have a shadow: can science respond? p885
Fleming Carswell
doi:10.1038/35082235
Call to work together on microarray data analysis p885
Kimberly Johnson and Simon Lin
doi:10.1038/35082237
Medical luminaries p885
Edgar Pick
doi:10.1038/35082239
Book Reviews
Speaking of learning p887
How do we acquire our marvellous facility for expressing ourselves in words?
Massimo Piattelli-Palmarini reviews Pathways to Language: From Fetus to Adolescent by Kyra Karmiloff and Annette Karmiloff-Smith
doi:10.1038/35082123
The birth of matter p888
Hans A. Bethe reviews The Magic Furnace: The Search for the Origins of Atoms by Marcus Chown
doi:10.1038/35082126
Geometry down the centuries p888
Jeremy Gray reviews Euclid's Window: The Story of Geometry from Parallel Lines to Hyperspace by Leonard Mlodinow
doi:10.1038/35082129
Universal knowledge p889
Theodore P. Snow reviews Encyclopedia of Astronomy and Astrophysics, Vols 1–4
doi:10.1038/35082131
New in paperback p889
doi:10.1038/35082133
Star-gazing made easy p890
doi:10.1038/35082135
New Journals p890
doi:10.1038/35082138
words
Risk and uncertainty p891
At the frontiers of science, we don't always know what may happen.
Robert May
doi:10.1038/35082158
News and Views
Non-stick water p895
Adding a simple powder to a drop of water gives it remarkable properties: the powder-coated drop no longer sticks to surfaces, and moves by rolling, much as a solid sphere would.
L. Mahadevan
doi:10.1038/35082164
Structural biology: Chlorophylls galore p896
A high-resolution crystal structure of photosystem I, part of the machinery that performs photosynthesis, reveals how an extensive array of chlorophylls uses solar energy to transport electrons.
Werner Kühlbrandt
doi:10.1038/35082169
100 and 50 years ago p897
doi:10.1038/35082172
Astronomy: Giants in the asteroid belt p899
Models of Solar System formation have always had a hard time explaining the mysterious asteroid belt. By injecting new life into an old myth about the origin of asteroids, astronomers may now have the answer.
Derek C. Richardson
doi:10.1038/35082174
Evolutionary biology: Seeing red in speciation p900
Mating patterns in sticklebacks have been investigated for over fifty years. The latest studies show how a complex interplay between males, females and the environment can contribute to the formation of new species.
Michael J. Ryan
doi:10.1038/35082176
Condensed-matter physics: Nickel probes superconductivity p901
Magnetism usually destroys superconductivity, but a magnetic nickel atom inserted into a high-temperature superconductor has surprisingly little effect on its local environment.
Michael E. Flatté
doi:10.1038/35082179
Neuroscience: Awareness of space p903
Damage to particular parts of the brain can cause spatial confusion and even eliminate awareness of areas of space around the body. The brain regions responsible for spatial awareness, however, are still under debate.
Michael S. A. Graziano
doi:10.1038/35082182
Ecology: Dairy declines hard to swallow p904
Birds are important constituents of any ecosystem. But they are also valuable monitors of environmental conditions — if their populations begin to decline, we need to know why.
Peter D. Moore
doi:10.1038/35082185
Daedalus: Stored rail energy p905
David Jones
doi:10.1038/35082188
Obituary: Frederick Gillett (1937–2001) p906
Frank Low
doi:10.1038/35082190
Brief Communications
The web of human sexual contacts p907
Promiscuous individuals are the vulnerable nodes to target in safe-sex campaigns.
Fredrik Liljeros, Christofer R. Edling, Luís A. Nunes Amaral, H. Eugene Stanley and Yvonne Åberg
doi:10.1038/35082140
Biomechanics: Turning the key on Drosophila audition p908
Martin C. Göpfert and Daniel Robert
doi:10.1038/35082144
First paragraph | Full Text | PDF (184K)
Article
Three-dimensional structure of cyanobacterial photosystem I at 2.5 Å resolution p909
Patrick Jordan,
Petra Fromme,
Horst Tobias Witt,
Olaf Klukas,
Wolfram Saenger
and
Norbert Krau
doi:10.1038/35082000
Abstract | Full Text | PDF (985K) | Supplementary information
See also: News and Views by Kühlbrandt
Letters to Nature
Skyrmions in a ferromagnetic Bose–Einstein condensate p918
Usama Al Khawaja and Henk Stoof
doi:10.1038/35082010
First paragraph | Full Text | PDF (185K)
Interplay of magnetism and high-Tc superconductivity at individual Ni impurity atoms in Bi2Sr2CaCu2O8+
p920
E. W. Hudson, K. M. Lang, V. Madhavan, S. H. Pan, H. Eisaki, S. Uchida and J. C. Davis
doi:10.1038/35082019
First paragraph | Full Text | PDF (326K)
See also: News and Views by Flatté
Liquid marbles p924
Pascale Aussillous and David Quéré
doi:10.1038/35082026
First paragraph | Full Text | PDF (259K)
See also: News and Views by Mahadevan
Decreasing overflow from the Nordic seas into the Atlantic Ocean through the Faroe Bank channel since 1950 p927
Bogi Hansen, William R. Turrell and Svein Østerhus
doi:10.1038/35082034
First paragraph | Full Text | PDF (441K)
Metamorphic core complex formation by density inversion and lower-crust extrusion p930
Fernando Martinez, Andrew M. Goodliffe and Brian Taylor
doi:10.1038/35082042
First paragraph | Full Text | PDF (475K)
The elastic constants of MgSiO3 perovskite at pressures and temperatures of the Earth's mantle p934
Artem R. Oganov, John P. Brodholt and G. David Price
doi:10.1038/35082048
First paragraph | Full Text | PDF (753K)
Major fungal lineages are derived from lichen symbiotic ancestors p937
François Lutzoni, Mark Pagel and Valérie Reeb
doi:10.1038/35082053
First paragraph | Full Text | PDF (925K) | Supplementary information
Phylogenetic analyses do not support horizontal gene transfers from bacteria to vertebrates p940
Michael J. Stanhope, Andrei Lupas, Michael J. Italia, Kristin K. Koretke, Craig Volker and James R. Brown
doi:10.1038/35082058
First paragraph | Full Text | PDF (355K) | Supplementary information
Divergent sexual selection enhances reproductive isolation in sticklebacks p944
Janette Wenrick Boughman
doi:10.1038/35082064
First paragraph | Full Text | PDF (175K)
See also: News and Views by Ryan
Nodulation of legumes by members of the 
-subclass of Proteobacteria p948
Lionel Moulin, Antonio Munive, Bernard Dreyfus and Catherine Boivin-Masson
doi:10.1038/35082070
First paragraph | Full Text | PDF (398K)
Spatial awareness is a function of the temporal not the posterior parietal lobe p950
Hans-Otto Karnath, Susanne Ferber and Marc Himmelbach
doi:10.1038/35082075
First paragraph | Full Text | PDF (237K) | Supplementary information
See also: News and Views by Graziano
Single neurons in prefrontal cortex encode abstract rules p953
Jonathan D. Wallis, Kathleen C. Anderson and Earl K. Miller
doi:10.1038/35082081
First paragraph | Full Text | PDF (330K)
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition p957
Huai-hu Chuang, Elizabeth D. Prescott, Haeyoung Kong, Shannon Shields, Sven-Eric Jordt, Allan I. Basbaum, Moses V. Chao and David Julius
doi:10.1038/35082088
First paragraph | Full Text | PDF (388K) | Supplementary information
Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer p962
F. Ango, L. Prézeau, T. Muller, J. C. Tu, B. Xiao, P. F. Worley, J. P. Pin, J. Bockaert and L. Fagni
doi:10.1038/35082096
First paragraph | Full Text | PDF (261K)
Nodal signalling in the epiblast patterns the early mouse embryo p965
Jane Brennan, Cindy C. Lu, Dominic P. Norris, Tristan A. Rodriguez, Rosa S. P. Beddington and Elizabeth J. Robertson
doi:10.1038/35082103
First paragraph | Full Text | PDF (327K) | Supplementary information
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses p969
Shideng Bao, Randal S. Tibbetts, Kathryn M. Brumbaugh, Yanan Fang, D. Ashley Richardson, Ambereen Ali, Susan M. Chen, Robert T. Abraham and Xiao-Fan Wang
doi:10.1038/35082110
First paragraph | Full Text | PDF (295K)
correction: Gain-assisted superluminal light propagation p974
L. J. Wang, A. Kuzmich and A. Dogariu
doi:10.1038/35082117
correction: Genomic analysis of metastasis reveals an essential role for RhoC p974
E. A. Clark, T. R. Golub, E. S. Lander and R. O. Hynes
doi:10.1038/35082119
correction: Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses p974
R. I. Wilson and R. A. Nicoll
doi:10.1038/35082121
New on the Market
Protein growth area p975
Cunning plans such as distributed computing are speeding up proteomics.
doi:10.1038/35082147