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Nature 411, 834-842 (14 June 2001) | doi:10.1038/35081168
Open Innovation Challenges
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Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
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Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
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review article Gene silencing as an adaptive defence against viruses
Peter M. Waterhouse1, Ming-Bo Wang1 & Tony Lough2
Abstract
Gene silencing was perceived initially as an unpredictable and inconvenient side effect of introducing transgenes into plants. It now seems that it is the consequence of accidentally triggering the plant's adaptive defence mechanism against viruses and transposable elements. This recently discovered mechanism, although mechanistically different, has a number of parallels with the immune system of mammals.
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