Naturejobs

Physics comes full circle p3

Paul Smaglik

doi:10.1038/35108014

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Biology, Policy, Physics p4

doi:10.1038/35108017

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Opinion

Next steps against AIDS p1009

The South African government at last has an opportunity to fight AIDS with drugs at reduced prices without fear of legal action. The country has the capacity to make significant progress. The government should make use of it.

doi:10.1038/35074243

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Astronomy, goddesses and knowledge p1009

Conflict between science and spiritual traditions in Hawaii can be overcome by common interests.

doi:10.1038/35074245

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News

Russia needs help to fend off potato famine, researchers warn p1011

Quirin Schiermeier

doi:10.1038/35074247

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Smithsonian closure plan under fire p1011

Josette Chen

doi:10.1038/35074250

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Standards needed for foot-and-mouth tests p1012

Sally Goodman

doi:10.1038/35074252

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Reef gets off the starting blocks p1012

David Adam

doi:10.1038/35074255

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Japan speeds up mission to unravel genetic diseases p1013

David Cyranoski

doi:10.1038/35074258

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South Africa may keep door closed to generic AIDS drugs p1013

Michael Cherry

doi:10.1038/35074261

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US administration tries to repair green image p1014

Mark Schrope

doi:10.1038/35074264

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Tenure-track plan aims to end university inbreeding p1014

Xavier Bosch

doi:10.1038/35074267

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Astronomers bargain for use of 'sacred' site p1015

Tony Reichhardt

doi:10.1038/35074270

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Weapons lab seeks Mexican link p1015

Rex Dalton

doi:10.1038/35074273

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news in brief p1016

doi:10.1038/35074275

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news feature

Cinderella goes to the ball p1018

After decades of neglect, research into 'innate' immunity has moved to centre stage. Phyllida Brown explores the excitement that now surrounds an evolutionarily ancient arm of our immune system.

Phyllida Brown

doi:10.1038/35074279

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Correspondence

Even 'free access' is still beyond the means of most scholars in Africa p1021

Paul Keese

doi:10.1038/35074190

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Precarious life in Spain p1021

Manuel J. Pérez Mendoza for Precarios

doi:10.1038/35074192

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Let's reward innovative action against poverty p1021

Arnoldo Ventura

doi:10.1038/35074194

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Entropy illustrates the flexibility of Chinese p1021

Jian Feng

doi:10.1038/35074196

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Commentaries

Access all areas? p1023

The Internet has revolutionized how we live and work — with dynamic new technologies it is set to change the way in which science reaches its audience.

doi:10.1038/35074204

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Publishing on the semantic web p1023

The coming Internet revolution will profoundly affect scientific information.

doi:10.1038/35074206

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The self-archiving initiative p1024

Freeing the refereed research literature online.

doi:10.1038/35074210

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Setting logical priorities p1026

A boycott is not the best route to free exchange of scientific information.

doi:10.1038/35074213

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Book Reviews

An instant in time p1027

How the atomic clock revolutionized time-keeping.

Daniel Kleppner reviews Splitting the Second: The Story of Atomic Time by Tony Jones

doi:10.1038/35074156

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When space and time conspire p1028

Michael F. Shlesinger reviews Complex Systems: Chaos and Beyond by Kunihiko Kaneko and Ichiro Tsuda

doi:10.1038/35074159

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Thinking the unthinkable p1029

Richard Gregory reviews The Origins of Creativity

doi:10.1038/35074162

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Measuring the past p1030

Michael Vickers reviews All Done with Mirrors by J. F. Neal

doi:10.1038/35074165

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A passion for butterflies p1030

doi:10.1038/35074168

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words

Scientist's birthright p1031

How a new name embodied ideals of connection and inclusiveness.

Dennis Danielson

doi:10.1038/35074216

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concepts

The genomic cosmos p1033

Mark C. Fishman

doi:10.1038/35074219

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News and Views

Polio vaccines exonerated p1035

One theory about the origin of the AIDS pandemic is that the virus responsible, HIV, was transmitted to humans from chimpanzees through contaminated polio vaccine. That theory fails some crucial tests.

Robin A. Weiss

doi:10.1038/35074222

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Palaeontology: Ruffling feathers p1036

The evolution of feathers and flight were generally thought to be inextricably linked. But new fossils from China show that feathers pre-dated the origin of flight and of birds.

Hans-Dieter Sues

doi:10.1038/35074225

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Optics: Holograms of atoms p1037

X-ray crystallography can be used to produce three-dimensional images of atoms providing they are arranged periodically. For small atomic clusters or molecules, electron holography could provide even sharper images.

John Spence

doi:10.1038/35074228

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100 and 50 years ago p1037

doi:10.1038/35074231

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Genome sequencing: A grin without a cat p1040

In some types of unicellular algae, the chloroplasts have their own nucleus — a legacy of the time when the chloroplast was a free-living cell. The sequence of the genome in one such nucleus is now revealed.

Paul R. Gilson and Geoffrey I. McFadden

doi:10.1038/35074233

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Earth science: Shaken, not stirred p1041

It is difficult to obtain a dynamic picture of the Earth's mantle. A study involving geophysical observations with geochemical implications shows that compositionally distinct megablobs contribute to the ebb and flow.

Michael Manga

doi:10.1038/35074235

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Cancer: Improved mouse models p1043

Mice that have been genetically modified to be prone to tumours are thought to be poor models of sporadic cancer. This problem can be tackled with a new generation of modified mice.

Anton Berns

doi:10.1038/35074238

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Daedalus: New life p1044

David Jones

doi:10.1038/35074241

Full Text | PDF (145K)

Brief Communications

Polio vaccine samples not linked to AIDS p1045

A search through the archives clears early vaccines of starting the AIDS pandemic.

Philippe Blancou, Jean-Pierre Vartanian, Cindy Christopherson, Nicole Chenciner, Claudio Basilico, Shirley Kwok and Simon Wain-Hobson

doi:10.1038/35074171

First paragraph | Full Text | PDF (180K) | Supplementary information

See also: News and Views by Weiss

Vaccine safety: Analysis of oral polio vaccine CHAT stocks p1046

N. Berry, C. Davis, A. Jenkins, D. Wood, P. Minor, G. Schild, M. Bottiger, H. Holmes and N. Almond

doi:10.1038/35074176

First paragraph | Full Text | PDF (145K)

See also: News and Views by Weiss

Human immunodeficiency virus: Phylogeny and the origin of HIV-1 p1047

Andrew Rambaut, David L. Robertson, Oliver G. Pybus, Martine Peeters and Edward C. Holmes

doi:10.1038/35074179

First paragraph | Full Text | PDF (166K) | Supplementary information

See also: News and Views by Weiss

Chronobiology: Reversal of honeybee behavioural rhythms p1048

Guy Bloch and Gene E. Robinson

doi:10.1038/35074183

First paragraph | Full Text | PDF (156K)

Articles

Deep-mantle high-viscosity flow and thermochemical structure inferred from seismic and geodynamic data p1049

Alessandro M. Forte and Jerry X. Mitrovica

doi:10.1038/35074000

Abstract | Full Text | PDF (803K) | Supplementary information

See also: News and Views by Manga

Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse p1057

Weichun Lin, Robert W. Burgess, Bertha Dominguez, Samuel L. Pfaff, Joshua R. Sanes and Kuo-Fen Lee

doi:10.1038/35074025

Abstract | Full Text | PDF (641K)

Letters to Nature

A phenomenological description of space-time noise in quantum gravity p1065

Giovanni Amelino-Camelia

doi:10.1038/35074035

First paragraph | Full Text | PDF (129K)

Entanglement purification for quantum communication p1067

Jian-Wei Pan, Christoph Simon, aslav Brukner and Anton Zeilinger

doi:10.1038/35074041

First paragraph | Full Text | PDF (143K)

Mobile silver ions and glass formation in solid electrolytes p1070

P. Boolchand and W. J. Bresser

doi:10.1038/35074049

First paragraph | Full Text | PDF (241K) | Supplementary information

Absence of deep-water formation in the Labrador Sea during the last interglacial period p1073

C. Hillaire-Marcel, A. de Vernal, G. Bilodeau and A. J. Weaver

doi:10.1038/35074059

First paragraph | Full Text | PDF (383K)

Evidence from the Pacific troposphere for large global sources of oxygenated organic compounds p1078

H. Singh, Y. Chen, A. Staudt, D. Jacob, D. Blake, B. Heikes and J. Snow

doi:10.1038/35074067

First paragraph | Full Text | PDF (192K)

Hemispherical variations in seismic velocity at the top of the Earth's inner core p1081

Fenglin Niu and Lianxing Wen

doi:10.1038/35074073

First paragraph | Full Text | PDF (816K)

The distribution of integumentary structures in a feathered dinosaur p1084

Qiang Ji, Mark A. Norell, Ke-Qin Gao, Shu-An Ji and Dong Ren

doi:10.1038/35074079

First paragraph | Full Text | PDF (846K) | Supplementary information

See also: News and Views by Sues

Genetic evidence for Near-Eastern origins of European cattle p1088

Christopher S. Troy, David E. MacHugh, Jillian F. Bailey, David A. Magee, Ronan T. Loftus, Patrick Cunningham, Andrew T. Chamberlain, Bryan C. Sykes and Daniel G. Bradley

doi:10.1038/35074088

First paragraph | Full Text | PDF (379K)

The highly reduced genome of an enslaved algal nucleus p1091

Susan Douglas, Stefan Zauner, Martin Fraunholz, Margaret Beaton, Susanne Penny, Lang-Tuo Deng, Xiaonan Wu, Michael Reith, Thomas Cavalier-Smith and Uwe-G Maier

doi:10.1038/35074092

First paragraph | Full Text | PDF (210K) | Supplementary information

See also: News and Views by Gilson & McFadden

Nonlinear effects of large-scale climatic variability on wild and domestic herbivores p1096

Atle Mysterud, Nils Chr. Stenseth, Nigel G. Yoccoz, Rolf Langvatn and Geir Steinheim

doi:10.1038/35074099

First paragraph | Full Text | PDF (194K)

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 p1099

Fumitaka Hayashi, Kelly D. Smith, Adrian Ozinsky, Thomas R. Hawn, Eugene C. Yi, David R. Goodlett, Jimmy K. Eng, Shizuo Akira, David M. Underhill and Alan Aderem

doi:10.1038/35074106

First paragraph | Full Text | PDF (187K)

TREM-1 amplifies inflammation and is a crucial mediator of septic shock p1103

Axel Bouchon, Fabio Facchetti, Markus A. Weigand and Marco Colonna

doi:10.1038/35074114

First paragraph | Full Text | PDF (454K)

IFN and lymphocytes prevent primary tumour development and shape tumour immunogenicity p1107

Vijay Shankaran, Hiroaki Ikeda, Allen T. Bruce, J. Michael White, Paul E. Swanson, Lloyd J. Old and Robert D. Schreiber

doi:10.1038/35074122

First paragraph | Full Text | PDF (259K) | Supplementary information

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice p1111

Leisa Johnson, Kim Mercer, Doron Greenbaum, Roderick T. Bronson, Denise Crowley, David A. Tuveson and Tyler Jacks

doi:10.1038/35074129

First paragraph | Full Text | PDF (378K) | Supplementary information

See also: News and Views by Berns

CONSTANS mediates between the circadian clock and the control of flowering in Arabidopsis p1116

Paula Suárez-López, Kay Wheatley, Frances Robson, Hitoshi Onouchi, Federico Valverde and George Coupland

doi:10.1038/35074138

First paragraph | Full Text | PDF (354K)

Structure of the gating domain of a Ca²⁺-activated K⁺ channel complexed with Ca²⁺/calmodulin p1120

Maria A. Schumacher, Andre F. Rivard, Hans Peter Bächinger and John P. Adelman

doi:10.1038/35074145

First paragraph | Full Text | PDF (587K) | Supplementary information

Article

erratum: Increase in greenhouse forcing inferred from the outgoing longwave radiation spectra of the Earth in 1970 and 1997 p1124

John E. Harries, Helen E. Brindley, Pretty J. Sagoo and Richard J. Bantges

doi:10.1038/35074154

Full Text | PDF (166K)

New on the Market

Be prepared p1125

The theme this week is 'DNA/RNA preparation' and all that that entails.

doi:10.1038/35074186

Full Text | PDF (259K)