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Nature 410, 822-825 (12 April 2001) | doi:10.1038/35071088;
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Junior Research Groups (W1 / W2)
- Cluster of Excellence "Multimodal Computing and Interaction"
- Saarbruecken Germany
Postdoctoral Fellow / Research Associate
- Beth Israel Deaconess Medical Center/Harvard Medical School
- Boston, MA, USA
Leptin-regulated endocannabinoids are involved in maintaining food intake
Leptin is the primary signal through which the hypothalamus senses nutritional state and modulates food intake and energy balance. Leptin reduces food intake by upregulating anorexigenic (appetite-reducing) neuropeptides, such as α-melanocyte-stimulating hormone, and downregulating orexigenic (appetite-stimulating) factors, primarily neuropeptide Y.
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Abstract
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