Opinion

The proteome isn't genome II p725

The Human Genome Organisation was both a cheer-leader and a coordinator for genomics. But proteomics is a different beast, and the fledgling Human Proteome Organisation will struggle to find a similar role.

doi:10.1038/35071232

Full Text | PDF (78K)

An absence of angst p725

German science seems surprisingly comfortable with the concept of a research prize sponsored by a tobacco giant.

doi:10.1038/35071234

Full Text | PDF (78K)

News

Museum visitors take priority as Smithsonian curbs research p727

Josette Chen

doi:10.1038/35071236

Full Text | PDF (376K)

UK foot-and-mouth epidemic slows p727

Jim Giles

doi:10.1038/35071239

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Restrictions delay fossil hunts in Ethiopia p728

Rex Dalton

doi:10.1038/35071241

Full Text | PDF (446K)

PubMed Central offers deal on content p728

Meredith Wadman

doi:10.1038/35071244

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Funding battle heats up over large array p729

Jonathan Knight

doi:10.1038/35071247

Full Text | PDF (247K)

Biologists bugged by space station cuts and uncertainties p730

Tony Reichhardt

doi:10.1038/35071250

Full Text | PDF (255K)

Report fudges issue as South Africa fights on against HIV p730

Michael Cherry

doi:10.1038/35071252

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Researchers probe the link between virus and AIDS p730

Michael Cherry

doi:10.1038/35071255

Full Text | PDF (255K)

Bush favours research at Pentagon and NIH p731

Colin Macilwain

doi:10.1038/35071257

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news in brief p732

doi:10.1038/35071260

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news feature

Is it all just a pipe dream? p734

Researchers trying to turn nanotubes into storage systems for hydrogen fuel are finding that corporate funding and academic openness can be hard to combine. Catherine Zandonella delves into a carbon controversy.

Catherine Zandonella

doi:10.1038/35071183

Full Text | PDF (674K)

Making crops cry for help p736

Plants attacked by hungry herbivores can release chemicals that attract their assailants' predators. Could these responses be exploited to develop environmentally friendly pest-control strategies? John Whitfield investigates.

John Whitfield

doi:10.1038/35071188

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Correspondence

Silicon philanthropists follow a great tradition p739

Susan M. Fitzpatrick

doi:10.1038/35071264

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When DNA research menaces diversity p739

Elena Angulo

doi:10.1038/35071266

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Gulf syndrome research has passed peer review p739

Robert W. Haley

doi:10.1038/35071268

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PubMed Central decentralized p740

Edwin Sequeira, Johanna McEntyre and David Lipman

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Commentary

Science for the have-nots p741

Developed and developing nations can build better partnerships.

doi:10.1038/35071136

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Spring Books

Origins of inspiration p743

A four-dimensional view of two twentieth-century icons.

John Christie reviews Einstein, Picasso: Space, Time, and the Beauty that Causes Havoc by Arthur Miller

doi:10.1038/35071138

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... but what does 'blue' smell like? p744

Ilya Farber reviews Synaesthesia: The Strangest Thing by John Harrison

doi:10.1038/35071141

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Creationism by stealth p745

Jerry A. Coyne reviews Icons of Evolution: Science or Myth? Why Much of What We Teach About Evolution is Wrong by Jonathan Wells

doi:10.1038/35071144

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A pillar of molecular biology p746

Robert Bazell reviews Ahead of the Curve: David Baltimore's Life in Science by Shane Crotty

doi:10.1038/35071146

Full Text | PDF (423K)

What every woman knows p747

Sylvie Coyaud reviews Athena Unbound: The Advancement of Women in Science and Technology by Henry Etzkowitz, Carol Kemelgor and Brian Uzzi and The Gender and Science Reader

doi:10.1038/35071149

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Nothing to it! p748

John O'Connor reviews The Book of Nothing by John D. Barrow

doi:10.1038/35071152

Full Text | PDF (276K)

Dispelling the boredom p749

G. M. Whitesides reviews Stimulating Concepts in Chemistry and The New Chemistry: A Showcase for Modern Chemistry and its Applications

doi:10.1038/35071155

Full Text | PDF (319K)

A constructive scheme unravelled? p750

Michael Grubb reviews The Collapse of the Kyoto Protocol and the Struggle to Slow Global Warming by David Victor

doi:10.1038/35071158

Full Text | PDF (346K)

Knowing the value of nature p751

E. J. Milner-Gulland reviews Wild Solutions: How Biodiversity is Money in the Bank by Andrew Beattie and Paul R. Ehrlich

doi:10.1038/35071161

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Murder most putrid p752

Mark Benecke reviews Maggots, Murder and Men: Memories and Reflections of a Forensic Entomologist by Z. Erzinçliolu

doi:10.1038/35071164

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words

Being objective p753

The idea of scientists as impartial observers is hard to shake, but is complete detachment justified?

Mary Midgley

doi:10.1038/35071193

Full Text | PDF (188K)

concepts

Moving rhythms p755

Eve Marder

doi:10.1038/35071196

Full Text | PDF (266K)

News and Views

Pop-up disaster p757

New analyses of old data show that a devastating earthquake of 1897 stemmed from slippage of a hitherto unknown fault. That event illustrates what might happen elsewhere today.

Wayne Thatcher

doi:10.1038/35071199

Full Text | PDF (312K)

Reproductive biology: Out with a bang p758

Not many mammalian males die soon after mating — the phenomenon was thought to be limited to certain small marsupials. Its occurrence in a larger marsupial overturns previous ideas about why the strategy exists.

Stuart Humphries and David J. Stevens

doi:10.1038/35071202

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Condensed-matter physics: An expanding view of plutonium p759

Interactions between electrons make it hard to predict the properties of exotic metals, such as plutonium. Better calculations that include a thorough treatment of electronic structure are the answer.

R. C. Albers

doi:10.1038/35071205

Full Text | PDF (157K)

Biological catalysis: The hairpin's turn p761

A crystal structure of the hairpin ribozyme provides an atomic framework for understanding RNA catalysis, including features that may be common to both RNA and protein enzymes.

Scott A. Strobel and Sean P. Ryder

doi:10.1038/35071209

Full Text | PDF (179K)

100 and 50 years ago p762

doi:10.1038/35071212

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Physiology: A hunger for cannabinoids p763

Cannabinoids — molecules found naturally in the body, as well as in cannabis — stimulate appetite. Leptin, a hormone produced by body fat, decreases appetite. The effects of these molecules have now been linked.

Raphael Mechoulam and Ester Fride

doi:10.1038/35071214

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Global change: A piece in the CO₂ jigsaw p765

A study of the year-to-year variation in net CO₂ uptake by the oceans helps in assessing the mechanisms of global climate change.

Dorothee Bakker and Andrew Watson

doi:10.1038/35071216

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Cell cycle: Checking two steps p766

When their DNA is damaged, cells temporarily stop multiplying to prevent the build-up of mutations. Two types of delay triggered by ionizing radiation appear to have common molecular starting points.

Michael B. Kastan

doi:10.1038/35071218

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Daedalus: Flattening the flats p767

David Jones

doi:10.1038/35071221

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Obituary: Claude Shannon (1916–2001) p768

Robert Calderbank and Neil J. A. Sloane

doi:10.1038/35071223

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Brief Communications

Herculaneum victims of Vesuvius in ad 79 p769

The eruption's first surge instantly killed some people sheltering from the impact.

Giuseppe Mastrolorenzo, Pier P. Petrone, Mario Pagano, Alberto Incoronato, Peter J. Baxter, Antonio Canzanella and Luciano Fattore

doi:10.1038/35071167

First paragraph | Full Text | PDF (566K)

High-speed swimming: Enhanced power in yellowfin tuna p770

Stephen L. Katz, Douglas A. Syme and Robert E. Shadwick

doi:10.1038/35071170

First paragraph | Full Text | PDF (296K)

Environment: Superselective clay for radium uptake p771

Sridhar Komarneni, Naofumi Kozai and William J. Paulus

doi:10.1038/35071173

First paragraph | Full Text | PDF (153K)

Neanderthal DNA: Not just old but old and cold? p771

Colin I. Smith, Andrew T. Chamberlain, Michael S. Riley, Alan Cooper, Chris B. Stringer and Matthew J. Collins

doi:10.1038/35071177

First paragraph | Full Text | PDF (153K) | Supplementary information

reply: Not just old but old and cold? p772

Igor V. Ovchinnikov, Anders Götherström, Galina P. Romanova, Vitaliy M. Kharitonov, Kerstin Lidén and William Goodwin

doi:10.1038/35071181

First paragraph | Full Text | PDF (121K)

Review

The role of chaotic resonances in the Solar System p773

N. Murray and M. Holman

doi:10.1038/35071000

Abstract | Full Text | PDF (271K)

Article

Crystal structure of a hairpin ribozyme–inhibitor complex with implications for catalysis p780

Peter B. Rupert and Adrian R. Ferré-D'Amaré

doi:10.1038/35071009

Abstract | Full Text | PDF (442K) | Supplementary information

See also: News and Views by Strobel & Ryder

Letters to Nature

An auroral flare at Jupiter p787

J. H. Waite, Jr, G. R. Gladstone, W. S. Lewis, R. Goldstein, D. J. McComas, P. Riley, R. J. Walker, P. Robertson, S. Desai, J. T. Clarke and D. T. Young

doi:10.1038/35071018

First paragraph | Full Text | PDF (886K) | Supplementary information

Quantum computing in molecular magnets p789

Michael N. Leuenberger and Daniel Loss

doi:10.1038/35071024

First paragraph | Full Text | PDF (255K)

Correlated electrons in -plutonium within a dynamical mean-field picture p793

S. Y. Savrasov, G. Kotliar and E. Abrahams

doi:10.1038/35071035

First paragraph | Full Text | PDF (123K)

See also: News and Views by Albers

Optical polymer thin films with isotropic and anisotropic nano-corrugated surface topologies p796

Mohammed Ibn-Elhaj and Martin Schadt

doi:10.1038/35071039

First paragraph | Full Text | PDF (372K)

Removal of chlorofluorocarbons by increased mass exchange between the stratosphere and troposphere in a changing climate p799

Neal Butchart and Adam A. Scaife

doi:10.1038/35071047

First paragraph | Full Text | PDF (181K)

Control of cation concentrations in stream waters by surface soil processes in an Amazonian watershed p802

Daniel Markewitz, Eric A. Davidson, Ricardo de O. Figueiredo, Reynaldo L. Victoria and Alex V. Krusche

doi:10.1038/35071052

First paragraph | Full Text | PDF (207K)

Plateau 'pop-up' in the great 1897 Assam earthquake p806

Roger Bilham and Philip England

doi:10.1038/35071057

First paragraph | Full Text | PDF (220K)

See also: News and Views by Thatcher

Plant diversity enhances ecosystem responses to elevated CO₂ and nitrogen deposition p809

Peter B. Reich, Jean Knops, David Tilman, Joseph Craine, David Ellsworth, Mark Tjoelker, Tali Lee, David Wedin, Shahid Naeem, Dan Bahauddin, George Hendrey, Shibu Jose, Keith Wrage, Jenny Goth and Wendy Bengston

doi:10.1038/35071062

First paragraph | Full Text | PDF (146K) | Supplementary information

Chemical speciation drives hydrothermal vent ecology p813

George W. Luther, III, Tim F. Rozan, Martial Taillefert, Donald B. Nuzzio, Carol Di Meo, Timothy M. Shank, Richard A. Lutz and S. Craig Cary

doi:10.1038/35071069

First paragraph | Full Text | PDF (320K)

Perceiving visual expansion without optic flow p816

Paul R. Schrater, David C. Knill and Eero P. Simoncelli

doi:10.1038/35071075

First paragraph | Full Text | PDF (225K)

The motor side of depth vision p819

Kai Schreiber, J. Douglas Crawford, Michael Fetter and Douglas Tweed

doi:10.1038/35071081

First paragraph | Full Text | PDF (327K)

Leptin-regulated endocannabinoids are involved in maintaining food intake p822

Vincenzo Di Marzo, Sravan K. Goparaju, Lei Wang, Jie Liu, Sándor Bátkai, Zoltán Járai, Filomena Fezza, Grant I. Miura, Richard D. Palmiter, Takayuki Sugiura and George Kunos

doi:10.1038/35071088

First paragraph | Full Text | PDF (184K)

See also: News and Views by Mechoulam  & Fride

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages p825

Vasso Episkopou, Ruth Arkell, Paula M. Timmons, James J. Walsh, Rebecca L. Andrew and Daniel Swan

doi:10.1038/35071095

First paragraph | Full Text | PDF (477K)

Arkadia enhances nodal-related signalling to induce mesendoderm p830

Christiane Niederländer, James J. Walsh, Vasso Episkopou and C. Michael Jones

doi:10.1038/35071103

First paragraph | Full Text | PDF (485K) | Supplementary information

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell p834

Romas Geleziunas, Weiduan Xu, Kohsuke Takeda, Hidenori Ichijo and Warner C. Greene

doi:10.1038/35071111

First paragraph | Full Text | PDF (233K)

A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax p839

Hernando A. del Portillo, Carmen Fernandez-Becerra, Sharen Bowman, Karen Oliver, Martin Preuss, Cecilia P. Sanchez, Nick K. Schneider, Juan M. Villalobos, Marie-Adele Rajandream, David Harris, Luiz H. Pereira da Silva, Bart Barrell and Michael Lanzer

doi:10.1038/35071118

First paragraph | Full Text | PDF (210K)

The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis p842

Jacob Falck, Niels Mailand, Randi G. Syljuåsen, Jiri Bartek and Jiri Lukas

doi:10.1038/35071124

First paragraph | Full Text | PDF (309K)

See also: News and Views by Kastan

correction: arrow encodes an LDL-receptor-related protein essential for Wingless signalling p847

Marcel Wehrli, Scott T. Dougan, Kim Caldwell, Louise O'Keefe, Stephanie Schwartz, Dalit Vaizel-Ohayon, Eyal Schejter, Andrew Tomlinson and Stephen DiNardo

doi:10.1038/35071131

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erratum: Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase p847

Fumiko Toyoshima-Morimoti, Eri Taniguchi, Nobuko Shinya, Akihiro Iwamatsu and Eisuke Nishida

doi:10.1038/35071133

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Careers and Recruitment

Uncertainty of short-term contracts is turning talent away from science p849

The proper balance between fixed-term employment and permanent positions has yet to be determined, says Heike Langenberg.

Heike Langenberg

doi:10.1038/35071226

Full Text | PDF (358K)

Have your say p850

Heike Langenberg

doi:10.1038/35071230

Full Text | PDF (162K)