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Nature 410, 321-322 (15 March 2001) | doi:10.1038/35066677
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Senior Researcher in theoretical chemistry / physics
- Italian Institute of Technology
- Lecce, Italy
Organic Chemistry
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
Structural biology: Protein crystal mimics reality
Robert M. Macnab
Abstract
Flagellin, a protein in the bacterial flagellar motor, has resisted attempts at three-dimensional crystallization — until now. The crystal structure offers hints as to how filaments are able to switch helical states.
Bacteria such as Salmonella and Escherichia coli propel themselves through aqueous environments using flagella. The flagellum has two parts: the filament and the motor.
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