Opinion

Biomedical boom, forget the rest? p965

As the US budget looms, the repercussions that President Bush's campaign promises will have on research and on other government programmes are becoming all too clear. Researchers face a tough struggle in lobbying Congress.

doi:10.1038/35059263

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Europe's infrastructure failure p965

Despite expectations to the contrary, the European Commission has failed to back research facilities for the long term.

doi:10.1038/35059265

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News

European Union moves to curb moratorium on transgenic plants p967

Quirin Schiermeier

doi:10.1038/35059267

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Wheels start to turn for mutant mouse archive p967

Alison Abbott

doi:10.1038/35059270

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Canada's BSE fears 'groundless' p968

David Spurgeon

doi:10.1038/35059273

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India promises more earthquake research p968

K. S. Jayaraman

doi:10.1038/35059276

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First Bush budget set to favour life sciences p969

Matthew Davis

doi:10.1038/35059279

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Farming accused of eco-damage p969

Corie Lok

doi:10.1038/35059282

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Residents wait for return to Japanese volcano island p970

David Cyranoski

doi:10.1038/35059284

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Small payout over Green Bank telescope cheers astronomers p970

Irwin Goodwin

doi:10.1038/35059287

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Biologists urge US to build marine reserves p971

Mark Schrope

doi:10.1038/35059290

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Scientists seek solidarity in oaths p971

Paul Smaglik and Colin Macilwain

doi:10.1038/35059293

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Climate change offers bleak future p971

Quirin Schiermeier

doi:10.1038/35059295

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news in brief p972

doi:10.1038/35059297

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news feature

Let there be light p974

A silicon laser would revolutionize telecommunications, electronics and computing. Squeezing light out of silicon is no easy task, but Philip Ball discovers that researchers are becoming more optimistic about its light-emitting abilities.

Philip Ball

doi:10.1038/35059301

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Correspondence

Oxide formation: reaction details studied, reported in brief p977

Howard Maskill

doi:10.1038/35059310

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Varied ecosystems need different fire protection p977

Sheri L. Gutsell, Edward A. Johnson, Kiyoko Miyanishi, Jon E. Keeley, Matthew Dickinson and Simon R. J. Bridge

doi:10.1038/35059312

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Opposition to animal law is not lack of concern p977

Mary J. C. Hendrix

doi:10.1038/35059314

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Book Reviews

In search of unity p979

Is the poetry in the science or in its appropriation?

Philip Clayton reviews Science and Poetry by Mary Midgley

doi:10.1038/35059152

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Art in the plastic age p980

Mark D. Haw reviews The Impact of Modern Paints by Jo Crook and Tom Learner

doi:10.1038/35059155

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From the monastery to the laboratory p981

Brian Charlesworth reviews In Mendel's Footnotes: An Introduction to the Science and Technologies of Genes and Genetics from the 19th Century to the 22nd by Colin Tudge

doi:10.1038/35059158

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Corruption and its consequences p982

Frances Cairncross reviews Captive State: The Corporate Takeover of Britain by George Monbiot

doi:10.1038/35059162

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words

Lombroso and Tolstoy p983

An anthropologist's unwitting gift to literature.

Paolo Mazzarello

doi:10.1038/35059175

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concepts

The artistry of nature p985

Eshel Ben-Jacob and Herbert Levine

doi:10.1038/35059178

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Correction: p986

doi:10.1038/35059182

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News and Views

The bite of Allosaurus p987

A combination of analytical methods used in engineering and scanning techniques from medicine can be applied in some surprising areas of research — the biomechanics of dinosaur feeding, for instance.

Gregory M. Erickson

doi:10.1038/35059184

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Structural biology: A 3D view of sodium channels p988

The voltage-gated sodium channel is essential for nerve cells to function. But how does it work? A low-resolution, three-dimensional structure provides some provocative insights.

William A. Catterall

doi:10.1038/35059188

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Earth history: Sediments to planetary motion p991

Celestial mechanics has long been used as an aid for interpreting geological records. The compliment is being repaid through analysis of Mediterranean sediments.

Marie-France Loutre

doi:10.1038/35059192

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Ecology: Bagging the lag p992

New techniques for analysing the dynamics of moth populations in captivity could have broad implications for biodiversity and conservation research in general.

Michael E. Hochberg and Arthur E. Weis

doi:10.1038/35059194

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Turbulence: Go with the flow p993

Traditional devices for measuring turbulence have been unable to keep up with the latest developments in theory. But detectors derived from high-energy physics may narrow the gap between experiment and theory.

Itamar Procaccia

doi:10.1038/35059196

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100 and 50 years ago p993

doi:10.1038/35059199

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Obituary: Tom Kilburn (1921–2001) p996

Simon Lavington

doi:10.1038/35059201

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Brief Communications

Muscle strength in overwintering bears p997

Unlike humans, bears retain their muscle tone when moribund for long periods.

Henry J. Harlow, Tom Lohuis, Thomas D. I. Beck and Paul A. Iaizzo

doi:10.1038/35059165

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Public health: Particulate emission from biomass combustion p998

Art Fernandez, Sheldon B. Davis, Jost O. L. Wendt, Roberta Cenni, R. Scott Young and Mark L. Witten

doi:10.1038/35059169

First paragraph | Full Text | PDF (452K)

Palaeontology: An Early Cretaceous pellet p998

José L. Sanz, Luis M. Chiappe, Yolanda Fernádez-Jalvo, Francisco Ortega, Begoña Sánchez-Chillón, Francisco J. Poyato-Ariza and Bernardino P. Pérez-Moreno

doi:10.1038/35059172

First paragraph | Full Text | PDF (452K)

Molecular biology: Protein encoding by both DNA strands p1000

Mariano Labrador, Fabien Mongelard, Piedad Plata-Rengifo, Ellen M. Baxter, Victor G. Corces and Tatiana I. Gerasimova

doi:10.1038/35059000

First paragraph | Full Text | PDF (134K)

Articles

The impact of specialized enemies on the dimensionality of host dynamics p1001

Ottar N. Bjørnstad, Steven M. Sait, Nils C. Stenseth, David J. Thompson and Michael Begon

doi:10.1038/35059003

Abstract | Full Text | PDF (291K) | Supplementary information

See also: News and Views by Hochberg & Weis

Massive gene decay in the leprosy bacillus p1007

S. T. Cole, K. Eiglmeier, J. Parkhill, K. D. James, N. R. Thomson, P. R. Wheeler, N. Honoré, T. Garnier, C. Churcher, D. Harris, K. Mungall, D. Basham, D. Brown, T. Chillingworth, R. Connor, R. M. Davies, K. Devlin, S. Duthoy, T. Feltwell, A. Fraser, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, C. Lacroix, J. Maclean, S. Moule, L. Murphy, K. Oliver, M. A. Quail, M.-A. Rajandream, K. M. Rutherford, S. Rutter, K. Seeger, S. Simon, M. Simmonds, J. Skelton, R. Squares, S. Squares, K. Stevens, K. Taylor, S. Whitehead, J. R. Woodward and B. G. Barrell

doi:10.1038/35059006

Abstract | Full Text | PDF (548K) | Supplementary information

Letters to Nature

A dusty torus around the luminous young star LkH101 p1012

Peter G. Tuthill, John D. Monnier and William C. Danchi

doi:10.1038/35059014

First paragraph | Full Text | PDF (168K)

Experimental entanglement distillation and 'hidden' non-locality p1014

Paul G. Kwiat, Salvador Barraza-Lopez, André Stefanov and Nicolas Gisin

doi:10.1038/35059017

First paragraph | Full Text | PDF (227K)

Fluid particle accelerations in fully developed turbulence p1017

A. La Porta, Greg A. Voth, Alice M. Crawford, Jim Alexander and Eberhard Bodenschatz

doi:10.1038/35059027

First paragraph | Full Text | PDF (169K)

See also: News and Views by Procaccia

Prediction of absolute crystal-nucleation rate in hard-sphere colloids p1020

Stefan Auer and Daan Frenkel

doi:10.1038/35059035

First paragraph | Full Text | PDF (212K)

Formation of thermally stable alkylidene layers on a catalytically active surface p1023

El Mamoune Zahidi, Hicham Oudghiri-Hassani and Peter H. McBreen

doi:10.1038/35059047

First paragraph | Full Text | PDF (662K) | Supplementary information

Recent mass balance of polar ice sheets inferred from patterns of global sea-level change p1026

Jerry X. Mitrovica, Mark E. Tamisiea, James L. Davis and Glenn A. Milne

doi:10.1038/35059054

First paragraph | Full Text | PDF (643K) | Supplementary information

Geological constraints on tidal dissipation and dynamical ellipticity of the Earth over the past three million years p1029

Lucas J. Lourens, Rolf Wehausen and Hans J. Brumsack

doi:10.1038/35059062

First paragraph | Full Text | PDF (336K)

See also: News and Views by Loutre

Cranial design and function in a large theropod dinosaur p1033

Emily J. Rayfield, David B. Norman, Celeste C. Horner, John R. Horner, Paula May Smith, Jeffrey J. Thomason and Paul Upchurch

doi:10.1038/35059070

First paragraph | Full Text | PDF (398K)

See also: News and Views by Erickson

Genetic evidence against panmixia in the European eel p1037

Thierry Wirth and Louis Bernatchez

doi:10.1038/35059079

First paragraph | Full Text | PDF (687K)

Temporal dynamics of a neural solution to the aperture problem in visual area MT of macaque brain p1040

Christopher C. Pack and Richard T. Born

doi:10.1038/35059085

First paragraph | Full Text | PDF (136K)

A sodium-channel mutation causes isolated cardiac conduction disease p1043

Hanno L. Tan, Margreet T. E. Bink-Boelkens, Connie R. Bezzina, Prakash C. Viswanathan, Gertie C. M. Beaufort-Krol, Peter J. van Tintelen, Maarten P. van den Berg, Arthur A. M. Wilde and Jeffrey R. Balser

doi:10.1038/35059090

First paragraph | Full Text | PDF (258K)

The voltage-sensitive sodium channel is a bell-shaped molecule with several cavities p1047

Chikara Sato, Yutaka Ueno, Kiyoshi Asai, Katsutoshi Takahashi, Masahiko Sato, Andreas Engel and Yoshinori Fujiyoshi

doi:10.1038/35059098

First paragraph | Full Text | PDF (411K)

See also: News and Views by Catterall

RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III p1051

Srikumar Sinnarajah, Carmen W. Dessauer, Deepa Srikumar, Jun Chen, John Yuen, Solomon Yilma, John C. Dennis, Edward E. Morrison, Vitaly Vodyanoy and John H. Kehrl

doi:10.1038/35059104

First paragraph | Full Text | PDF (277K)

Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells p1055

Ofer Mandelboim, Niva Lieberman, Marianna Lev, Lada Paul, Tal I. Arnon, Yuri Bushkin, Daniel M. Davis, Jack L. Strominger, Jonathan W. Yewdell and Angel Porgador

doi:10.1038/35059110

First paragraph | Full Text | PDF (238K)

Identification of CRE1 as a cytokinin receptor from Arabidopsis p1060

Tsutomu Inoue, Masayuki Higuchi, Yukari Hashimoto, Motoaki Seki, Masatomo Kobayashi, Tomohiko Kato, Satoshi Tabata, Kazuo Shinozaki and Tatsuo Kakimoto

doi:10.1038/35059117

First paragraph | Full Text | PDF (272K) | Supplementary information

cdc2 links the Drosophila cell cycle and asymmetric division machineries p1063

Murni Tio, Gerald Udolph, Xiaohang Yang and William Chia

doi:10.1038/35059124

First paragraph | Full Text | PDF (330K)

Opposing effects of Ets and Id proteins on p16^INK4a expression during cellular senescence p1067

Naoko Ohtani, Zoe Zebedee, Thomas J. G. Huot, Julie A. Stinson, Masataka Sugimoto, Yasuhiro Ohashi, Andrew D. Sharrocks, Gordon Peters and Eiji Hara

doi:10.1038/35059131

First paragraph | Full Text | PDF (213K) | Supplementary information

Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 Å p1071

Kevin C. Slep, Michele A. Kercher, Wei He, Christopher W. Cowan, Theodore G. Wensel and Paul B. Sigler

doi:10.1038/35059138

First paragraph | Full Text | PDF (636K)

insight

Astrobiology p1079

doi:10.1038/35059204

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Desperately seeking aliens p1080

Brian W. Aldiss

doi:10.1038/35059207

Abstract | Full Text | PDF (244K)

The habitat and nature of early life p1083

E. G. Nisbet and N. H. Sleep

doi:10.1038/35059210

Abstract | Full Text | PDF (786K)

Life in extreme environments p1092

Lynn J. Rothschild and Rocco L. Mancinelli

doi:10.1038/35059215

Abstract | Full Text | PDF (925K)

Chance and necessity: the evolution of morphological complexity and diversity p1102

Sean B. Carroll

doi:10.1038/35059227

Abstract | Full Text | PDF (275K)

The search for extraterrestrial intelligence p1110

T. L. Wilson

doi:10.1038/35059235

Abstract | Full Text | PDF (194K)

Humans in space p1115

Ronald J. White and Maurice Averner

doi:10.1038/35059243

Abstract | Full Text | PDF (180K)

Where are the dolphins? p1119

Jack Cohen and Ian Stewart

doi:10.1038/35059248

Abstract | Full Text | PDF (358K)

New on the Market

Senescence and cell death p1123

Recent launches include kits to detect senescence in cells, and apoptosis.

doi:10.1038/35059147

Full Text | PDF (180K)