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Nature 409, 567-568 (1 February 2001) | doi:10.1038/35054637
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Postdoctoral Associate in Enzyme Biochemistry
- Cornell University
- Ithaca, New York
Senior Faculty Positions
- Torrey Pines Institute for Molecular Studies
- Port St. Lucie, FL
Fusion needs more than SNAREs
Wolfhard Almers
Abstract
Force biological membranes close enough together and they will fuse. SNARE proteins are well suited to force proximity. But biochemical studies of yeast show that proximity is not the only requirement.
The cells in our bodies are packed full of membrane-bounded compartments. These compartments exchange material by shedding small, cargo-carrying packets called vesicles, which then fuse their membrane with that of other compartments or with the plasma membrane.
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