FIGURE 4. Expression profiles of SBF and MBF targets.
From the following article:
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF
Vishwanath R. Iyer, Christine E. Horak, Charles S. Scafe, David Botstein, Michael Snyder and Patrick O. Brown
Nature 409, 533-538(25 January 2001)
doi:10.1038/35054095
a, Expression patterns of SBF and MBF targets are indicated (red–green colour scale). Cell-cycle data are from ref. 12 and sporulation data are from ref. 18. The stages of the cell cycle are: M/G1, yellow; G1, green; S, blue; S/G2l, red; and G2/M, orange. Yellow boxes indicate the presence of consensus binding sites in the intergenic sequences upstream of each ORF (right), and the median percentile rank in IPs of the upstream sequences is also indicated (blue–yellow colour scale), as in Fig. 3. For each set of targets, the top panel contains cell-cycle regulated genes, the bottom panel contains genes that are members of divergently transcribed pairs in which the other member was cell-cycle regulated, and the middle panel contains the remainder of the non-cell-cycle regulated genes. b, Average expression profiles of the cell-cycle regulated targets of SBF and MBF, computed by averaging the log 2 (Cy5/Cy3) ratios. Note the specific induction of MBF targets during sporulation.