FIGURE 2. Defining criteria for identifying SBF and MBF targets.

From the following article:

Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

Vishwanath R. Iyer, Christine E. Horak, Charles S. Scafe, David Botstein, Michael Snyder and Patrick O. Brown

Nature 409, 533-538(25 January 2001)

doi:10.1038/35054095

BACK TO ARTICLE

a, Distribution of median percentile ranks of Cy5/Cy3 fluorescence ratios from 11 independent microarray hybridizations analysing Swi4 binding. The threshold for defining SBF targets is indicated by a dotted line. b, Distribution of median ranks of Cy5/Cy3 fluorescence ratios from four independent microarray hybridizations analysing Swi6 and Mbp1 binding. c, Fraction of genes in a sliding 50-gene window whose expression profile has a correlation coefficient of greater than or equal to 0.5 with that of a canonical G1/S regulated gene, as a function of the median percentile ranks of Cy5/Cy3 fluorescence ratios from the MBF hybridizations. The threshold for defining MBF targets is indicated by a dotted line.

BACK TO ARTICLE