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Nature 409, 33-34 (4 January 2001) | doi:10.1038/35051208
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Assistant Professor
- University of Michigan
- Michigan, MI 48109 United States
Faculty Positions
- University of Texas Medical Branch
- Galveston, TX United States
DNA replication: SOS polymerases
Fumio Hanaoka
Abstract
The standard DNA-replicating machinery cannot copy damaged DNA, so SOS enzymes come to the rescue. It now seems, at least in some bacteria, that different enzymes are required for different types of damage.
Imagine that an injured person is carried into a hospital's emergency department. The doctor needs to assess the situation quickly, and to decide on the most appropriate treatment — stitches, a drug or maybe an operation?
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