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Nature 409, 24-27 (4 January 2001) | doi:10.1038/35051187

Open Innovation Challenges

Neurobiology: Background inhibition to the fore

Ivan Soltesz1 & Zoltan Nusser

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Investigations of a neurotransmitter receptor required for 'background' neuronal inhibition in mice show the importance of such inhibition in keeping neuronal excitability under control.

Why would you put microphones outside a concert hall to record the music inside? All they would pick up is muffled noise, although the sound would vary according to the music's highs and lows.

  1. Ivan Soltesz is in the Department of Anatomy and Neurobiology, University of California, Irvine, California 92697-1280, USA.
    e-mail: Email: isoltesz@uci.edu

Correspondence to: Zoltan Nusser Zoltan Nusser is in the Laboratory of Cellular Neurophysiology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony Street 43, 1083 Budapest, Hungary.
e-mail: Email: nusser@koki.hu