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Nature 408, 915-916 (21 December 2000) | doi:10.1038/35050179
Model behaviour
Paul F. Chapman
Abstract
Trials in mice of a possible vaccine for Alzheimer's disease show that it reduces the behavioural defects and the brain damage seen in the disease. As promising as these results are, a human vaccine remains a long way off.
The prospect of testing treatments for Alzheimer's disease is daunting. There are huge uncertainties about who is at risk and how the disease will progress in individual cases, so treatments might spend years in clinical trials in humans before their effects can be assessed with confidence.
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