Rebuttals of a controversial book that alleges malpractice by distinguished anthropologists have so far confused rather than clarified the situation. An independent inquiry is urgently needed.
doi:10.1038/35048713
Table of contents
Volume 408 Number 6814 pp755-884
Top of page
News
Japan to bypass bureaucracy by reshaping science ministries p757
Germany sets up electronic archive p757
Forces for collaboration falter with human genome in sight p758
Faster sequencing slows down release of mouse gene data p758
Japan pins hopes on fast-breeder nuclear option p759
Publication deal for Celera sparks row over data access p759
California invests $300 million in high tech p760
Pesticides implicated in declining frog numbers p760
Galapagos ecologists under threat from violent protests p761
Virtual laboratory will recreate classic experiments p761
Top of page
News Feature
Swimming against the tide p764
Toshio Yanagida rejects the conventional biophysical explanation of muscle contraction. No one doubts his technical genius, but could the debate he started ultimately hold back the field? David Cyranoski investigates.
David Cyranoski
doi:10.1038/35048748
Top of page
Correspondence
Beefing about the risks posed by the French BSE epidemic p767
Acid test finally wiped out vitalism, and yet . . . p767
. . . we need a metaphor to explain life's mystery p767
Ecology needs theory as well as practice p768
Pressure to meet current needs hinders science p768
Top of page
Book Reviews
Programmed for defence p769
doi:10.1038/35048623
Gene games of the future p769
doi:10.1038/35048626
Scientifically speaking p770
doi:10.1038/35048628
Extremophiles in the raw p771
New in paperback p771
Top of page
Millennium Essay
A cellular cornucopia p773
Stem cells generate new possibilities for research and therapy.
Margaret Buckingham
doi:10.1038/35048635
Top of page
Futures
The holdouts p775
The contrarians of physics get strung out in Chicago.
George Zebrowski
doi:10.1038/35048640
Top of page
News and Views
流体力学：平らな海で泳ぐ
Swimming in Flatsea p777
Some of the simplest questions are the hardest to answer. Why flags flap is a long-standing puzzle that becomes easier to solve in a two-dimensional world.
Greg Huber
doi:10.1038/35048643
100 and 50 years ago p778
doi:10.1038/35048646
進化発生生物学：頭の進化の始まり
Evolutionary developmental biology: Head start p778
Some neat transgenic experiments show how the evolution of the vertebrate head stemmed, at least in part, from elaboration of controls on pre-existing genetic machinery.
John R. Finnerty
doi:10.1038/35048648
凝縮系科学：液体の構造をつかまえる
Condensed-matter science: Five-fold symmetry in liquids p781
A complete description of the structure of simple liquids is missing from our understanding of matter. But new observations show that liquids contain many configurations with five-fold symmetry.
Frans Spaepen
doi:10.1038/35048652
RNAスプライシング：RNA酵素の場合
RNA splicing: The case for an RNA enzyme p782
New evidence suggests that RNA splicing, the removal of non-coding parts of a messenger RNA, is catalysed by an RNA component of the splicing machinery. This component binds a crucial metal ion.
Timothy W. Nilsen
doi:10.1038/35048655
超伝導：幾何学が生み出す渦
Superconductivity: Geometry spawns vortices p783
The properties of superconductors can be affected by their shape. This effect is increasingly noticeable as the size of the superconductor decreases.
Alan T. Dorsey
doi:10.1038/35048658
植物生物学：セキュリティー・システム
Plant biology: Volatile defence p785
Obituary: Michael Smith (1932–2000) p786
Top of page
Brief Communications
Likely size of the French BSE epidemic p787
Epidemiological analysis helps in evaluating the potential risks of eating French beef.
Christl A. Donnelly
doi:10.1038/35048666
Illusions: What you see is what you hear p788
Ladan Shams, Yukiyasu Kamitani and Shinsuke Shimojo
doi:10.1038/35048669
Biogeochemistry: Soil warming and organic carbon content p789
Eric A. Davidson, Susan E. Trumbore and Ronald Amundson
doi:10.1038/35048672
reply: Soil warming and organic carbon content p790
Christian P. Giardina and Michael G. Ryan
doi:10.1038/35048675
Top of page
news feature
news and views
Special
forewordA. thaliana genome p791
doi:10.1038/35048677
news feature
Now for the hard ones p792
Arabidopsis was an obvious choice for the first plant genome project, but it will never feed the world. David Adam reports on efforts to harvest the genomes of rice and other important crop plants.
David Adam
doi:10.1038/35048680
news and views
A green chapter in the book of life p794
The sequencing of an entire plant genome is now complete. The information it contains provides an unparalleled resource for understanding the evolution of flowering plants and the genetics of crop plants.
Virginia Walbot
doi:10.1038/35048685
Top of page
special
article遺伝：顕花植物シロイヌナズナのゲノム塩基配列の解析
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana p796
and The Arabidopsis Genome Initiative
doi:10.1038/35048692
Top of page
Special
letters to nature遺伝：シロイヌナズナの第1染色体の塩基配列解読と解析
Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana p816
Athanasios Theologis, Joseph R. Ecker, Curtis J. Palm, Nancy A. Federspiel, Samir Kaul, Owen White, Jose Alonso, Hootan Altafi, Rina Araujo, Cheryl L. Bowman, Shelise Y. Brooks, Eugen Buehler, April Chan, Qimin Chao, Huaming Chen, Rosa F. Cheuk, Christina W. Chin, Mike K. Chung, Lane Conn, Aaron B. Conway, Andrew R. Conway, Todd H. Creasy, Ken Dewar, Patrick Dunn, Pelin Etgu, Tamara V. Feldblyum, JiDong Feng, Betty Fong, Claire Y. Fujii, John E. Gill, Andrew D. Goldsmith, Brian Haas, Nancy F. Hansen, Beth Hughes, Lucas Huizar, Jonathan L. Hunter, Jennifer Jenkins, Chanda Johnson-Hopson, Shehnaz Khan, Elizabeth Khaykin, Christopher J. Kim, Hean L. Koo, Irina Kremenetskaia, David B. Kurtz, Andrea Kwan, Bao Lam, Stephanie Langin-Hooper, Andrew Lee, Jeong M. Lee, Catherine A. Lenz, Joycelyn. H. Li, YaPing Li, Xiaoying Lin, Shirley X. Liu, Zhaoying A. Liu, Jason S. Luros, Rama Maiti, Andre Marziali, Jennifer Militscher, Molly Miranda, Michelle Nguyen, William C. Nierman, Brian I. Osborne, Grace Pai, Jeremy Peterson, Paul K. Pham, Michael Rizzo, Timothy Rooney, Don Rowley, Hitomi Sakano, Steven L. Salzberg, Jody R. Schwartz, Paul Shinn, Audrey M. Southwick, Hui Sun, Luke J. Tallon, Gabriel Tambunga, Mitsue J. Toriumi, Christopher D. Town, Teresa Utterback, Susan Van Aken, Maria Vaysberg, Valentina S. Vysotskaia, Michelle Walker, Dongying Wu, Guixia Yu, Claire M. Fraser, J. Craig Venter and Ronald W. Davis
doi:10.1038/35048500
Top of page
special
letters to nature遺伝：シロイヌナズナの第3染色体の塩基配列解読と解析
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana p820
and European Union Chromosome 3 Arabidopsis Genome Sequencing Consortium and The Institute for Genomic Research and Kazusa DNA Research Institute
doi:10.1038/35048706
遺伝：シロイヌナズナの第5染色体の塩基配列解読と解析
Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana p823
and Kazusa DNA Research Institute and The Cold Spring Harbor and Washington University Sequencing Consortium and The European Union Arabidopsis Genome Sequencing Consortium and Institute of Plant Genetics and Crop Plant Research (IPK)
doi:10.1038/35048507
Top of page
Article
地球：海底近くの磁気異常から得られた過去78万年にわたる地磁気強度変化
Geomagnetic intensity variations over the past 780 kyr obtained from near-seafloor magnetic anomalies p827
Jeffrey S. Gee, Steven C. Cande, John A. Hildebrand, Katie Donnelly and Robert L. Parker
doi:10.1038/35048513
Top of page
Attenuation of FGF signalling in mouse
Letters to Nature
物性：メゾスコピック超伝導体における、対称性で誘起される反渦糸の形成
Symmetry-induced formation of antivortices in mesoscopic superconductors p833
Liviu F. Chibotaru, Arnout Ceulemans, Vital Bruyndoncx and Victor V. Moshchalkov
doi:10.1038/35048521
日本語要約 | Full Text | PDF (494K)
物理：二次元の風の中の一次元の旗に似ている、流れるセッケン薄膜中の柔軟な糸
Flexible filaments in a flowing soap film as a model for one-dimensional flags in a two-dimensional wind p835
Jun Zhang, Stephen Childress, Albert Libchaber and Michael Shelley
doi:10.1038/35048530
日本語要約 | Full Text | PDF (515K)
化学：液体鉛で観察された局所的5回対称性
Observation of five-fold local symmetry in liquid lead p839
H. Reichert, O. Klein, H. Dosch, M. Denk, V. Honkimäki, T. Lippmann and G. Reiter
doi:10.1038/35048537
日本語要約 | Full Text | PDF (236K)
気候：1998年のオクラホマ‐テキサス干ばつにおける海面水温と土壌水分フィードバックの役割
Role of sea surface temperature and soil-moisture feedback in the 1998 Oklahoma–Texas drought p842
地球：温度の低い沈み込んだスラブ内に高圧の氷が存在する可能性
Possible presence of high-pressure ice in cold subducting slabs p844
進化：進化における種−面積関係の解析
Analysis of an evolutionary species–area relationship p847
生態：サンゴの蛍光色素は光防護の働きをもつ
Fluorescent pigments in corals are photoprotective p850
Anya Salih, Anthony Larkum, Guy Cox, Michael Kühl and Ove Hoegh-Guldberg
doi:10.1038/35048564
日本語要約 | Full Text | PDF (308K)
進化：脊椎動物頭部の進化におけるHox遺伝子制御の保存性と新しい機能の獲得
Conservation and elaboration of Hox gene regulation during evolution of the vertebrate head p854
Miguel Manzanares, Hiroshi Wada, Nobue Itasaki, Paul A. Trainor, Robb Krumlauf and Peter W. H. Holland
doi:10.1038/35048570
日本語要約 | Full Text | PDF (256K)
生理：補足眼球野による行為の監視
Performance monitoring by the supplementary eye field p857
Veit Stuphorn, Tracy L. Taylor and Jeffrey D. Schall
doi:10.1038/35048576
神経：野生型H3受容体の高い常時活動による脳内ヒスタミンニューロン活動の調節
High constitutive activity of native H3 receptors regulates histamine neurons in brain p860
Séverine Morisset, Agnès Rouleau, Xavier Ligneau, Florence Gbahou, Joël Tardivel-Lacombe, Holger Stark, Walter Schunack, C. Robin Ganellin and Jean-Michel Arrang
doi:10.1038/35048583
日本語要約 | Full Text | PDF (438K)
医学：マウスβ細胞におけるFGF情報伝達の減衰が糖尿病に結びつく
Attenuation of FGF signalling in mouse 
-cells leads to diabetes p864
Alan W. Hart, Nathalie Baeza, Åsa Apelqvist and Helena Edlund
doi:10.1038/35048589
日本語要約 | Full Text | PDF (404K)
生理：ホスホグリセリン酸キナーゼは腫瘍の血管新生の過程でジスルフィド還元酵素として働く
Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase p869
Angelina J. Lay, Xing-Mai Jiang, Oliver Kisker, Evelyn Flynn, Anne Underwood, Rosemary Condron and Philip J. Hogg
doi:10.1038/35048596
日本語要約 | Full Text | PDF (252K)
細胞：ヒト生細胞のクロマチンで起こるヒストンH1.1の速い交換
Rapid exchange of histone H1.1 on chromatin in living human cells p873
Melody A. Lever, John P. H. Th'ng, Xuejun Sun and Michael J. Hendzel
doi:10.1038/35048603
日本語要約 | Full Text | PDF (238K)
細胞：生細胞で起こるヒストンH1とクロマチンの動的な結合
Dynamic binding of histone H1 to chromatin in living cells p877
Tom Misteli, Akash Gunjan, Robert Hock, Michael Bustin and David T. Brown
doi:10.1038/35048610
日本語要約 | Full Text | PDF (1,244K) | Supplementary information
細胞：U6核内低分子RNAによる金属イオンの配位はスプライソソーム内の触媒作用を助ける
Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome p881
Shyue-Lee Yean, Gerald Wuenschell, John Termini and Ren-Jang Lin
doi:10.1038/35048617
日本語要約 | Full Text | PDF (185K)
