Table of contents


Top

Opinion

Restoring faith in anthropology p755

Rebuttals of a controversial book that alleges malpractice by distinguished anthropologists have so far confused rather than clarified the situation. An independent inquiry is urgently needed.

doi:10.1038/35048713


Top

News

Japan to bypass bureaucracy by reshaping science ministries p757

David Cyranoski and Robert Triendl

doi:10.1038/35048715


Germany sets up electronic archive p757

Quirin Schiermeier

doi:10.1038/35048718


Forces for collaboration falter with human genome in sight p758

Paul Smaglik

doi:10.1038/35048720


Faster sequencing slows down release of mouse gene data p758

Paul Smaglik

doi:10.1038/35048724


Japan pins hopes on fast-breeder nuclear option p759

David Cyranoski

doi:10.1038/35048727


Publication deal for Celera sparks row over data access p759

Paul Smaglik

doi:10.1038/35048730


California invests $300 million in high tech p760

Rex Dalton

doi:10.1038/35048733


Pesticides implicated in declining frog numbers p760

Jessa Netting

doi:10.1038/35048736


Galapagos ecologists under threat from violent protests p761

Mark Schrope

doi:10.1038/35048739


Virtual laboratory will recreate classic experiments p761

Vera Bettenworth and Alison Abbott

doi:10.1038/35048742


News in brief p762

doi:10.1038/35048745


Top

News Feature

Swimming against the tide p764

Toshio Yanagida rejects the conventional biophysical explanation of muscle contraction. No one doubts his technical genius, but could the debate he started ultimately hold back the field? David Cyranoski investigates.

David Cyranoski

doi:10.1038/35048748


Top

Correspondence

Beefing about the risks posed by the French BSE epidemic p767

John Krebs

doi:10.1038/35048753


Acid test finally wiped out vitalism, and yet . . . p767

Sidney Toby

doi:10.1038/35048755


. . . we need a metaphor to explain life's mystery p767

Richard Strohman

doi:10.1038/35048757


Ecology needs theory as well as practice p768

Brian A. Maurer

doi:10.1038/35048759


Pressure to meet current needs hinders science p768

Rodney W. Nichols

doi:10.1038/35048761


Top

Book Reviews

Programmed for defence p769

Fred Rosen reviews The War Within Us: Everyman's Guide to Infection and Immunity by Cedric Mims

doi:10.1038/35048623


Gene games of the future p769

Veronica van Heyningen reviews Engineering the Human Germline: An Exploration of the Science and Ethics of Altering the Genes We Pass to Our Children

doi:10.1038/35048626


Scientifically speaking p770

doi:10.1038/35048628


Extremophiles in the raw p771

P. G. Willmer reviews The Surprising Archaea: Discovering Another Domain of Life by John L. Howland

doi:10.1038/35048631


New in paperback p771

doi:10.1038/35048633


Top

Millennium Essay

A cellular cornucopia p773

Stem cells generate new possibilities for research and therapy.

Margaret Buckingham

doi:10.1038/35048635


Top

Futures

The holdouts p775

The contrarians of physics get strung out in Chicago.

George Zebrowski

doi:10.1038/35048640


Top

News and Views

Swimming in Flatsea p777

Some of the simplest questions are the hardest to answer. Why flags flap is a long-standing puzzle that becomes easier to solve in a two-dimensional world.

Greg Huber

doi:10.1038/35048643


100 and 50 years ago p778

doi:10.1038/35048646


Evolutionary developmental biology: Head start p778

Some neat transgenic experiments show how the evolution of the vertebrate head stemmed, at least in part, from elaboration of controls on pre-existing genetic machinery.

John R. Finnerty

doi:10.1038/35048648


Condensed-matter science: Five-fold symmetry in liquids p781

A complete description of the structure of simple liquids is missing from our understanding of matter. But new observations show that liquids contain many configurations with five-fold symmetry.

Frans Spaepen

doi:10.1038/35048652


RNA splicing: The case for an RNA enzyme p782

New evidence suggests that RNA splicing, the removal of non-coding parts of a messenger RNA, is catalysed by an RNA component of the splicing machinery. This component binds a crucial metal ion.

Timothy W. Nilsen

doi:10.1038/35048655


Superconductivity: Geometry spawns vortices p783

The properties of superconductors can be affected by their shape. This effect is increasingly noticeable as the size of the superconductor decreases.

Alan T. Dorsey

doi:10.1038/35048658


Plant biology: Volatile defence p785

Amanda Tromans

doi:10.1038/35048660


Obituary: Michael Smith (1932–2000) p786

Michael R. Hayden and Victor Ling

doi:10.1038/35048663


Top

Brief Communications

Likely size of the French BSE epidemic p787

Epidemiological analysis helps in evaluating the potential risks of eating French beef.

Christl A. Donnelly

doi:10.1038/35048666


Illusions: What you see is what you hear p788

Ladan Shams, Yukiyasu Kamitani and Shinsuke Shimojo

doi:10.1038/35048669


Biogeochemistry: Soil warming and organic carbon content p789

Eric A. Davidson, Susan E. Trumbore and Ronald Amundson

doi:10.1038/35048672


reply: Soil warming and organic carbon content p790

Christian P. Giardina and Michael G. Ryan

doi:10.1038/35048675


Top

Special

foreword

A. thaliana genome p791

doi:10.1038/35048677


news feature

Now for the hard ones p792

Arabidopsis was an obvious choice for the first plant genome project, but it will never feed the world. David Adam reports on efforts to harvest the genomes of rice and other important crop plants.

David Adam

doi:10.1038/35048680


news and views

A green chapter in the book of life p794

The sequencing of an entire plant genome is now complete. The information it contains provides an unparalleled resource for understanding the evolution of flowering plants and the genetics of crop plants.

Virginia Walbot

doi:10.1038/35048685


Top

special

article

Analysis of the genome sequence of the flowering plant Arabidopsis thaliana p796

and The Arabidopsis Genome Initiative

doi:10.1038/35048692


Top

Special

letters to nature

Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana p816

Athanasios Theologis, Joseph R. Ecker, Curtis J. Palm, Nancy A. Federspiel, Samir Kaul, Owen White, Jose Alonso, Hootan Altafi, Rina Araujo, Cheryl L. Bowman, Shelise Y. Brooks, Eugen Buehler, April Chan, Qimin Chao, Huaming Chen, Rosa F. Cheuk, Christina W. Chin, Mike K. Chung, Lane Conn, Aaron B. Conway, Andrew R. Conway, Todd H. Creasy, Ken Dewar, Patrick Dunn, Pelin Etgu, Tamara V. Feldblyum, JiDong Feng, Betty Fong, Claire Y. Fujii, John E. Gill, Andrew D. Goldsmith, Brian Haas, Nancy F. Hansen, Beth Hughes, Lucas Huizar, Jonathan L. Hunter, Jennifer Jenkins, Chanda Johnson-Hopson, Shehnaz Khan, Elizabeth Khaykin, Christopher J. Kim, Hean L. Koo, Irina Kremenetskaia, David B. Kurtz, Andrea Kwan, Bao Lam, Stephanie Langin-Hooper, Andrew Lee, Jeong M. Lee, Catherine A. Lenz, Joycelyn. H. Li, YaPing Li, Xiaoying Lin, Shirley X. Liu, Zhaoying A. Liu, Jason S. Luros, Rama Maiti, Andre Marziali, Jennifer Militscher, Molly Miranda, Michelle Nguyen, William C. Nierman, Brian I. Osborne, Grace Pai, Jeremy Peterson, Paul K. Pham, Michael Rizzo, Timothy Rooney, Don Rowley, Hitomi Sakano, Steven L. Salzberg, Jody R. Schwartz, Paul Shinn, Audrey M. Southwick, Hui Sun, Luke J. Tallon, Gabriel Tambunga, Mitsue J. Toriumi, Christopher D. Town, Teresa Utterback, Susan Van Aken, Maria Vaysberg, Valentina S. Vysotskaia, Michelle Walker, Dongying Wu, Guixia Yu, Claire M. Fraser, J. Craig Venter and Ronald W. Davis

doi:10.1038/35048500


Top

special

letters to nature

Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana p820

and European Union Chromosome 3 Arabidopsis Genome Sequencing Consortium and The Institute for Genomic Research and Kazusa DNA Research Institute

doi:10.1038/35048706


Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana p823

and Kazusa DNA Research Institute and The Cold Spring Harbor and Washington University Sequencing Consortium and The European Union Arabidopsis Genome Sequencing Consortium and Institute of Plant Genetics and Crop Plant Research (IPK)

doi:10.1038/35048507


Top

Article

Geomagnetic intensity variations over the past 780 kyr obtained from near-seafloor magnetic anomalies p827

Jeffrey S. Gee, Steven C. Cande, John A. Hildebrand, Katie Donnelly and Robert L. Parker

doi:10.1038/35048513


Top

Letters to Nature

Symmetry-induced formation of antivortices in mesoscopic superconductors p833

Liviu F. Chibotaru, Arnout Ceulemans, Vital Bruyndoncx and Victor V. Moshchalkov

doi:10.1038/35048521

See also: News and Views by Dorsey


Flexible filaments in a flowing soap film as a model for one-dimensional flags in a two-dimensional wind p835

Jun Zhang, Stephen Childress, Albert Libchaber and Michael Shelley

doi:10.1038/35048530

See also: News and Views by Huber


Observation of five-fold local symmetry in liquid lead p839

H. Reichert, O. Klein, H. Dosch, M. Denk, V. Honkimäki, T. Lippmann and G. Reiter

doi:10.1038/35048537

See also: News and Views by Spaepen


Role of sea surface temperature and soil-moisture feedback in the 1998 Oklahoma–Texas drought p842

Song-You Hong and Eugenia Kalnay

doi:10.1038/35048548


Possible presence of high-pressure ice in cold subducting slabs p844

Craig R. Bina and Alexandra Navrotsky

doi:10.1038/35048555


Analysis of an evolutionary species–area relationship p847

Jonathan B. Losos and Dolph Schluter

doi:10.1038/35048558


Fluorescent pigments in corals are photoprotective p850

Anya Salih, Anthony Larkum, Guy Cox, Michael Kühl and Ove Hoegh-Guldberg

doi:10.1038/35048564


Conservation and elaboration of Hox gene regulation during evolution of the vertebrate head p854

Miguel Manzanares, Hiroshi Wada, Nobue Itasaki, Paul A. Trainor, Robb Krumlauf and Peter W. H. Holland

doi:10.1038/35048570

See also: News and Views by Finnerty


Performance monitoring by the supplementary eye field p857

Veit Stuphorn, Tracy L. Taylor and Jeffrey D. Schall

doi:10.1038/35048576


High constitutive activity of native H3 receptors regulates histamine neurons in brain p860

Séverine Morisset, Agnès Rouleau, Xavier Ligneau, Florence Gbahou, Joël Tardivel-Lacombe, Holger Stark, Walter Schunack, C. Robin Ganellin and Jean-Michel Arrang

doi:10.1038/35048583


Attenuation of FGF signalling in mouse beta-cells leads to diabetes p864

Alan W. Hart, Nathalie Baeza, Åsa Apelqvist and Helena Edlund

doi:10.1038/35048589


Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase p869

Angelina J. Lay, Xing-Mai Jiang, Oliver Kisker, Evelyn Flynn, Anne Underwood, Rosemary Condron and Philip J. Hogg

doi:10.1038/35048596


Rapid exchange of histone H1.1 on chromatin in living human cells p873

Melody A. Lever, John P. H. Th'ng, Xuejun Sun and Michael J. Hendzel

doi:10.1038/35048603


Dynamic binding of histone H1 to chromatin in living cells p877

Tom Misteli, Akash Gunjan, Robert Hock, Michael Bustin and David T. Brown

doi:10.1038/35048610


Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome p881

Shyue-Lee Yean, Gerald Wuenschell, John Termini and Ren-Jang Lin

doi:10.1038/35048617

See also: News and Views by Nilsen


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