Table of contents

Correspondence

Important differences between sources of embryonic stem cells p513

Anne McLaren

doi:10.1038/35046266

Full Text | PDF (80K)

Weak euro hits PhDs too p513

Luis Graca, Susana Nery, Monica Bettencourt Dias and Tiago Magalhaes

doi:10.1038/35046268

Full Text | PDF (80K)

Bernoulli was ahead of modern epidemiology p513

Klaus Dietz and J. A. P. Heesterbeek

doi:10.1038/35046270

Full Text | PDF (80K)

Aquaculture: part of the problem, not a solution p514

Julio E. Pérez, Mauro Nirchio and Juan A. Gomez

doi:10.1038/35046272

Full Text | PDF (67K)

Funding would prevent waste of research time p514

Pedro Martínez

doi:10.1038/35046274

Full Text | PDF (67K)

Book Reviews

Innovations to stir young minds p515

Curiosity may have killed the cat, but for tomorrow's scientists it is essential.

Howard P. Segal reviews Supreme Machines: Aircraft by Moira Butterfield and The Need for Speed Racing Cars by Philip Raby and Inventions and Discoveries: The Facts Behind Amazing Breakthroughs That Changed the World by Peter Harrison and The Oxford Children's Encyclopedia of Science & Technology and How Things Work Today edited by Michael Wright & Mukul Patel and Wow! Inventions that Changed the World by Philip Ardagh

doi:10.1038/35046139

Full Text | PDF (344K)

Presents you may want to read as well p516

Tim Brosnan reviews Usborne Guide to e-mail by Mark Wallace and Philippa Wingate and How to Build a Robot by Clive Gifford and Crashing Computers by Michael Coleman and How the Future Began by Clive Gifford and Terminal Chic by Chloë Rayban

doi:10.1038/35046142

Full Text | PDF (290K)

Spiders need friends too p516

Jeremy N. McNeil reviews Each Living Thing by Joanne Ryder and Wild and Free by Mike Manning and Brita Granström and Going, Going, Gone by Barbara Taylor and Garbage by Robert Maass and I Want To Be An Environmentalist by Stephanie Maze and Planet Zoo: One Hundred Animals We Can't Afford to Lose by Simon Barnes

doi:10.1038/35046144

Full Text | PDF (290K)

The facts of life and death p517

Andrew Berry reviews Chomp! Munch! Chew! by Karen Wallace and Ross Collins and It Takes Two by Karen Wallace and Ross Collins and I Didn't Know that Wolves Howl at the Moon by Cecilia Fitzsimmons and Zooming and Creeping by Barbara Taylor

doi:10.1038/35046148

Full Text | PDF (181K)

Empirical curiosity . . . in verse p518

Maurice Riordan reviews Centrally Heated Knickers by Michael Rosen and Points of View with Professor Peekaboo by John Agard and All Sorts by Christopher Reid

doi:10.1038/35046151

Full Text | PDF (168K)

Trailing nature p518

Sandra Knapp reviews Cave by Diane Siebert and Dory Story by Jerry Pallotta and Rosie Plants a Radish by Kate Petty and This is the Tree by Miriam Moss and The Great Kapok Tree: A Tale of the Amazon Rain Forest by Lynne Cherry and The Usborne First Encyclopedia of Animals and Oxford First Book of Animals by Barbara Taylor and All Kinds of Habitats by Sally Hewitt and Misunderstood Bats/Misunderstood Chameleons by Arthur John L'Hommedieu and The Oxford Children's Encyclopedia of Plants and Animals by OUP and A Leaf in Time by David Walker and Youch! It Bites: Real-life Monsters, Up Close by Trevor Day and Journey to Freedom by Colin Dann and Lion Country by Colin Dann and Wild Things Books: Baboon Rock/Leopard Trail/Lion Pride by Elizabeth Laird and Usborne Science & Experiments: Ecology by Richard Spurgeon

doi:10.1038/35046153

Full Text | PDF (168K)

Dinos all around p519

Kevin Padian reviews Time Tunnel by Arthur John L'Hommedieu and Jigsaw Dinosaurs by Anne Sharp and Going, Going, Gone by Barbara Taylor and Feathered Dinosaurs by Christopher Sloan and Dinosaurs by Joachim Oppermann and Dinosaurs by Sue Nicholson and Dinosaures: Les Seigneurs de la Terre by Paul Barrett & Jose Luis Sanz and Dinosaurs: The Ultimate Guide to Prehistoric Life by Christopher A. Brochu

doi:10.1038/35046157

Full Text | PDF (209K)

Launching kids' minds into space p520

Monica M. Grady reviews The Sun is My Favorite Star by Frank Asch and Zoo in the Sky by Jacqueline Mitton & Christina Balit and Touchdown Mars! by Peggy Wethered, Ken Edgett and Michael Chesworth and DK Guide to Space: A Photographic Journey Through the Universe by Peter Bond and The Kingfisher Book of Space by Martin Redfern and Marshall mini: Space and The Usborne Complete Book of Astronomy & Space by Lisa Miles and Alastair Smith and Journey to the Stars by Stewart Clark and Asteroid Impact by Douglas Henderson and How to Live on Mars: Hands-on Guide to Being a Science Superstar by Clive Gifford and Space Race by Sylvia Waugh

doi:10.1038/35046160

Full Text | PDF (192K)

Images of Earth p521

Lawrence W. Braile reviews The Kingfisher Young People's Book of Planet Earth by Martin Redfern and 3-Dimensional Earth by Sean Connolly and Nature's Fury: Eyewitness Reports of Natural Disasters by Carole G. Vogel and Discovering El Niño: How Fable and Fact Together Help Explain the Weather by Patricia Seibert and The Usborne Encyclopedia of Planet Earth by Anna Claybourne, Gillian Doherty and Rebecca Treays and Time Life Student Library: Planet Earth edited by Jean Burke Crawford and The Oxford Children's Encyclopedia of Our World edited by Ben Dupré and The Usborne First Encyclopedia of Our World by Felicity Brooks

doi:10.1038/35046163

Full Text | PDF (177K)

Hurricanes and lightning p522

Cornelia Lüdecke reviews Unser Wetter by Angela Weinhold and The Weatherbirds: An Incredible Journey Through the Weather of the World by Ted Dewan and Wetter by John Farndon and Wetterstation and Weather & Climate by Fiona Watt and Francis Wilson and Stormy Weather by Anita Ganeri and Wind und Wetter by Frederike Vogel and Christoph Kraul and Kachelmanns Wetterstation by Jörg Kachelmann and Alexander Lehmann

doi:10.1038/35046165

Full Text | PDF (118K)

Horribly fun and dreadfully popular! p522

Sandra Knapp reviews Horrible Science Series and Horrible Geography Series

doi:10.1038/35046167

Full Text | PDF (118K)

Millennium Essay

What dreams may come? p523

The scientific benefits of eating cheese before bedtime.

Paolo Mazzarello

doi:10.1038/35046170

Full Text | PDF (160K)

Futures

Too many memories p525

Sit down and tell me your story. I'm listening.

Pamela Sargent

doi:10.1038/35046173

Full Text | PDF (89K)

News and Views

Fighting the Ebola virus p527

A vaccine that protects monkeys against a lethal dose of Ebola virus has been developed. But there is still a lot to learn about how this vaccine works before a version that can protect humans is available.

Dennis R. Burton and Paul W. H. I. Parren

doi:10.1038/35046176

Full Text | PDF (141K)

Superconductivity: C₆₀ — the hole story p528

Superconductivity has been demonstrated at a surprisingly high temperature in a C₆₀ solid, raising questions about its electronic properties and hopes of even higher temperatures to come.

Olle Gunnarsson

doi:10.1038/35046179

Full Text | PDF (106K)

Evolutionary biology: The problem of variation p529

One genetic source of the sex-specific variation in pigmentation patterns of different fruitfly species has been identified. This study illustrates the power of bringing together developmental and evolutionary biology.

David L. Stern

doi:10.1038/35046183

Full Text | PDF (130K)

Nanotechnology: Pinning on impact p531

Magdalena Helmer

doi:10.1038/35046185

Full Text | PDF (105K)

100 and 50 years ago p532

doi:10.1038/35046188

Full Text | PDF (185K)

Biogeography: Chile refuges p532

Where did warmth-loving species shelter from the cold during ice ages? Genetic analyses of a coniferous tree in South America provide an unexpected answer.

Peter D. Moore

doi:10.1038/35046190

Full Text | PDF (185K)

Earthquake science: Shaking faults loose p533

Earthquakes often induce aftershocks on other faults, but the mechanisms remain elusive. An innovative analysis tells us more about the effects of dynamic stresses caused by the passage of seismic waves.

Chris Marone

doi:10.1038/35046193

Full Text | PDF (257K)

Osteoimmunology: Bone versus immune system p535

A molecule on activated T cells triggers bone loss by switching on bone-resorbing cells. Fortunately, it seems that this mechanism is kept in check by another molecule, secreted by the T cells.

Joseph R. Arron and Yongwon Choi

doi:10.1038/35046196

Full Text | PDF (349K)

Brief Communications

Cultural revolution in whale songs p537

Humpbacks have picked up a catchy tune sung by immigrants from a distant ocean.

Michael J. Noad, Douglas H. Cato, M. M. Bryden, Micheline -N. Jenner and K. Curt S. Jenner

doi:10.1038/35046199

First paragraph | Full Text | PDF (952K)

Alloys: A stable binary quasicrystal p537

A. P. Tsai, J. Q. Guo, E. Abe, H. Takakura and T. J. Sato

doi:10.1038/35046202

First paragraph | Full Text | PDF (952K)

Development: DNA methylation in Drosophila melanogaster p538

Frank Lyko, Bernard H. Ramsahoye and Rudolf Jaenisch

doi:10.1038/35046205

First paragraph | Full Text | PDF (1,036K)

Analytical dynamics: Numismatic gyrations p540

Ger van den Engh, Peter Nelson and Jared Roach

doi:10.1038/35046209

First paragraph | Full Text | PDF (85K)

reply: Numismatic gyrations p540

H. K. Moffatt

doi:10.1038/35046211

First paragraph | Full Text | PDF (85K)

Review

Electronics using hybrid-molecular and mono-molecular devices p541

C. Joachim, J. K. Gimzewski and A. Aviram

doi:10.1038/35046000

Abstract | Full Text | PDF (412K)

Articles

Superconductivity at 52 K in hole-doped C₆₀ p549

J. H. Schön, Ch. Kloc and B. Batlogg

doi:10.1038/35046008

Abstract | Full Text | PDF (270K)

Genetic control and evolution of sexually dimorphic characters in Drosophila p553

Artyom Kopp, Ian Duncan and Sean B. Carroll

doi:10.1038/35046017

Abstract | Full Text | PDF (653K) | Supplementary information

Letters to Nature

Evidence against a redshift z > 6 for the galaxy STIS123627+621755 p560

Daniel Stern, Peter Eisenhardt, Hyron Spinrad, Steve Dawson, Wil van Breugel, Arjun Dey, Wim de Vries and S. A. Stanford

doi:10.1038/35046027

First paragraph | Full Text | PDF (181K)

Unusual spectral energy distribution of a galaxy previously reported to be at redshift 6.68 p562

Hsiao-Wen Chen, Kenneth M. Lanzetta, Sebastian Pascarelle and Noriaki Yahata

doi:10.1038/35046031

First paragraph | Full Text | PDF (139K)

First-order transition in confined water between high-density liquid and low-density amorphous phases p564

Kenichiro Koga, Hideki Tanaka and X. C. Zeng

doi:10.1038/35046035

First paragraph | Full Text | PDF (286K)

Changes in deep-water formation during the Younger Dryas event inferred from ¹⁰Be and ¹⁴C records p567

Raimund Muscheler, Jürg Beer, Gerhard Wagner and Robert C. Finkel

doi:10.1038/35046041

First paragraph | Full Text | PDF (323K)

Triggering of earthquake aftershocks by dynamic stresses p570

Deborah Kilb, Joan Gomberg and Paul Bodin

doi:10.1038/35046046

First paragraph | Full Text | PDF (242K)

Geochemical evidence for terrestrial ecosystems 2.6 billion years ago p574

Yumiko Watanabe, Jacques E. J. Martini and Hiroshi Ohmoto

doi:10.1038/35046052

First paragraph | Full Text | PDF (528K)

Nutritional constraints in terrestrial and freshwater food webs p578

James J. Elser, William F. Fagan, Robert F. Denno, Dean R. Dobberfuhl, Ayoola Folarin, Andrea Huberty, Sebastian Interlandi, Susan S. Kilham, Edward McCauley, Kimberly L. Schulz, Evan H. Siemann and Robert W. Sterner

doi:10.1038/35046058

First paragraph | Full Text | PDF (126K)

Bacterial dehalorespiration with chlorinated benzenes p580

Lorenz Adrian, Ulrich Szewzyk, Jörg Wecke and Helmut Görisch

doi:10.1038/35046063

First paragraph | Full Text | PDF (190K)

Calcium stores regulate the polarity and input specificity of synaptic modification p584

Makoto Nishiyama, Kyonsoo Hong, Katsuhiko Mikoshiba, Mu-ming Poo and Kunio Kato

doi:10.1038/35046067

First paragraph | Full Text | PDF (473K) | Supplementary information

Analysis of calcium channels in single spines using optical fluctuation analysis p589

Bernardo L. Sabatini and Karel Svoboda

doi:10.1038/35046076

First paragraph | Full Text | PDF (366K)

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast p593

Tomokazu Ohshiro, Takako Yagami, Chuan Zhang and Fumio Matsuzaki

doi:10.1038/35046087

First paragraph | Full Text | PDF (386K)

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts p596

Chian-Yu Peng, Laurina Manning, Roger Albertson and Chris Q. Doe

doi:10.1038/35046094

First paragraph | Full Text | PDF (397K) | Supplementary information

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN- p600

Hiroshi Takayanagi, Kouetsu Ogasawara, Shigeaki Hida, Tomoki Chiba, Shigeo Murata, Kojiro Sato, Akinori Takaoka, Taeko Yokochi, Hiromi Oda, Keiji Tanaka, Kozo Nakamura and Tadatsugu Taniguchi

doi:10.1038/35046102

First paragraph | Full Text | PDF (385K)

Development of a preventive vaccine for Ebola virus infection in primates p605

Nancy J. Sullivan, Anthony Sanchez, Pierre E. Rollin, Zhi-yong Yang and Gary J. Nabel

doi:10.1038/35046108

First paragraph | Full Text | PDF (162K)

Coenzyme Q is an obligatory cofactor for uncoupling protein function p609

Karim S. Echtay, Edith Winkler and Martin Klingenberg

doi:10.1038/35046114

First paragraph | Full Text | PDF (193K)

The PSI-H subunit of photosystem I is essential for state transitions in plant photosynthesis p613

Christina Lunde, Poul Erik Jensen, Anna Haldrup, Juergen Knoetzel and Henrik Vibe Scheller

doi:10.1038/35046121

First paragraph | Full Text | PDF (157K)

addendum: Magnetoresistance from quantum interference effects in ferromagnets p616

N. Manyala, Y. Sidis, J. F. DiTusa, G. Aeppli, D. P. Young and Z. Fisk

doi:10.1038/35046129

correction: Ultrasensitive pheromone detection by mammalian vomeronasal neurons p616

Trese Leinders-Zufall, Andrew P. Lane, Adam C. Puche , Weidong Ma, Milos V. Novotny, Michael T. Shipley and Frank Zufall

doi:10.1038/35046131

erratum: Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase p616

Sandra van Wilpe, Michael T. Ryan, Kerstin Hill, Ammy C. Maarse, Chris Meisinger, Jan Brix, Peter J. T. Dekker, Martin Moczko, Richard Wagner, Michiel Meijer, Bernard Guiard, Angelika Hönlinger and Nikolaus Pfanner

doi:10.1038/35046134

erratum: Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1 p616

Stacey S. Huppert, Anh Le, Eric H. Schroeter, Jeffrey S. Mumm, Meera T. Saxena, Laurie A. Milner and Raphael Kopan

doi:10.1038/35046136

New on the Market

Looking for new gear for 2001? p617

Enter a photomicrographic beauty contest, go to the library for lipids.

doi:10.1038/35046213

Full Text | PDF (338K)

Careers and Recruitment

Governments prime basic nanotech research, applied activity yet to soar p619

Hype or reality? Is nanotechnology just a clever rebranding, or a profound change in our world view? The answer is: both, says Helen Gavaghan.

Helen Gavaghan

doi:10.1038/35046276

Full Text | PDF (173K)

Britain turns its attention to nanotech transfer p620

Alok Jha

doi:10.1038/35046280

Full Text | PDF (197K)

A flexible approach p621

Alok Jha

doi:10.1038/35046282

Full Text | PDF (215K)

US industry starts to think big by acting small p621

Paul Smaglik

doi:10.1038/35046285

Full Text | PDF (215K)

Building for the future p622

Paul Smaglik

doi:10.1038/35046289

Full Text | PDF (157K)

Canada tries to limit nanotech brain drain p623

David Spurgeon

doi:10.1038/35046291

Nanotech undergrad course available p623

David Spurgeon

doi:10.1038/35046294

Japan sets sights on success in nanotechnology p624

David Cyranoski

doi:10.1038/35046296

Land of opportunity p624

David Cyranoski

doi:10.1038/35046299