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TY  - JOUR
TI  - American Cancer Society
JA  - Cancer Facts
and Figures 2000
PY  - 2000///
SP  - 1
EP  - 7
ER  -

TY  - JOUR
AU  - Bishop, J. M.
TI  - 
Molecular themes in oncogenesis
JA  - Cell
PY  - 1991///
VL  - 64
SP  - 
235
EP  - 248
M3  - 10.1016/0092-8674(91)90636-D
N1  - 10.1016/0092-8674(91)90636-D
UR  - http://dx.doi.org/10.1016/0092-8674(91)90636-D
ER  -

TY  - JOUR
AU  - Nowell, P. C.
TI  - 
The clonal evolution of tumor cell populations
JA  - Science
PY  - 1976///
VL  - 
194
SP  - 23
EP  - 28
ER  -

TY  - JOUR
AU  - Vogelstein, B.
TI  - Genetic alterations during colorectal-tumor development
JA  - 
N. Engl. J. Med.
PY  - 1988///
VL  - 319
SP  - 525
EP  - 532
ER  -

TY  - JOUR
AU  - Balaban, G. B.
AU  - 
Herlyn, M.
AU  - Clark, W. H., 
AU  - Nowell, P. C.
TI  - 
Karyotypic evolution in human malignant melanoma
JA  - Cancer Genet.
Cytogenet.
PY  - 1986///
VL  - 19
SP  - 113
EP  - 122
ER  -

TY  - JOUR
AU  - Naylor, S. L.
AU  - 
Johnson, B. E.
AU  - Minna, J.
D.
AU  - Sakaguchi, A. Y.
TI  - 
Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer

JA  - Nature
PY  - 1987///
VL  - 329
SP  - 451
EP  - 454
M3  - 10.1038/329451a0
N1  - 10.1038/329451a0
UR  - http://dx.doi.org/10.1038/329451a0
ER  -

TY  - JOUR
AU  - James, C. D.
TI  - Clonal genomic alterations in glioma malignancy stages
JA  - 
Cancer Res.
PY  - 1988///
VL  - 48
SP  - 5546
EP  - 5551
ER  -

TY  - JOUR
AU  - Rabinovitch, P. S.
AU  - 
Reid, B. J.
AU  - Haggitt, R. C.

AU  - Norwood, T. H.
AU  - 
Rubin, C. E.
TI  - Progression to cancer in Barrett's
esophagus is associated with genomic instability
JA  - Lab. Invest.

PY  - 1988///
VL  - 60
SP  - 65
EP  - 71
ER  -

TY  - JOUR
AU  - Harman, D.
TI  - 
Aging: a theory based on free-radical and radiation chemistry
JA  - 
J. Gerontol.
PY  - 1956///
VL  - 6
SP  - 298
EP  - 300
ER  -

TY  - JOUR
AU  - Ames, B. N.
AU  - 
Shigenaga, M. K.
AU  - Hagen, 
T. M.
TI  - Oxidants, antioxidants and the degenerative diseases
of aging
JA  - Proc. Natl Acad. Sci. USA
PY  - 1993///
VL  - 90
SP  - 
7915
EP  - 7922
ER  -

TY  - JOUR
AU  - Minnick, D. T.
AU  - Kunkel, T. A.
TI  - DNA synthesis
errors, mutators and cancer
JA  - Cancer Surv.
PY  - 1996///
VL  - 28
SP  - 
3
EP  - 20
ER  -

TY  - JOUR
AU  - Oller, A. R.
AU  - 
Rastogi, P.
AU  - Morgenthaler, 
S.
AU  - Thilly, W. G.
TI  - 
A statistical model to estimate variance in long term-low dose mutation assays:
testing of the model in a human lymphoblastoid mutation assay
JA  - 
Mutat. Res.
PY  - 1989///
VL  - 216
SP  - 149
EP  - 161
M3  - 10.1016/0165-1161(89)90001-0
N1  - 10.1016/0165-1161(89)90001-0
UR  - http://dx.doi.org/10.1016/0165-1161(89)90001-0
ER  -

TY  - JOUR
AU  - Jackson, A. L.
AU  - Loeb, L. A.
TI  - The mutation rate
and cancer
JA  - Genetics
PY  - 1998///
VL  - 148
SP  - 1483
EP  - 
1490
ER  -

TY  - JOUR
AU  - Armitage, P.
AU  - 
Doll, R.
TI  - The age distribution of cancer and
a multi-stage theory of carcinogenesis
JA  - Br. J. Cancer
PY  - 1954///
VL  - 
8
SP  - 1
EP  - 12
ER  -

TY  - JOUR
AU  - Renan, M. J.
TI  - 
How many mutations are required for tumorigenesis? Implications from human
cancer data
JA  - Mol. Carcinog.
PY  - 1993///
VL  - 7
SP  - 139
EP  - 
146
ER  -

TY  - JOUR
AU  - Hanahan, D.
AU  - 
Weinberg, R. A.
TI  - The hallmarks of cancer
JA  - 
Cell
PY  - 2000///
VL  - 100
SP  - 57
EP  - 70
M3  - 10.1016/S0092-8674(00)81683-9
N1  - 10.1016/S0092-8674(00)81683-9
UR  - http://dx.doi.org/10.1016/S0092-8674(00)81683-9
ER  -

TY  - JOUR
AU  - Loeb, L. A.
TI  - 
Mutator phenotype may be required for multistage carcinogenesis
JA  - 
Cancer Res.
PY  - 1991///
VL  - 51
SP  - 3075
EP  - 3079
ER  -

TY  - JOUR
AU  - Kinzler, K. W.
AU  - Vogelstein, B.
TI  - Lessons from
hereditary colorectal cancer
JA  - Cell
PY  - 1996///
VL  - 87
SP  - 159

EP  - 170
M3  - 10.1016/S0092-8674(00)81333-1
N1  - 10.1016/S0092-8674(00)81333-1
UR  - http://dx.doi.org/10.1016/S0092-8674(00)81333-1
ER  -

TY  - JOUR
AU  - Lengauer, C.
AU  - 
Kinzler, K. W.
AU  - Vogelstein, 
B.
TI  - Genetic instability in colorectal cancers
JA  - 
Nature
PY  - 1997///
VL  - 386
SP  - 623
EP  - 627
M3  - 10.1038/386623a0
N1  - 10.1038/386623a0
UR  - http://dx.doi.org/10.1038/386623a0
ER  -

TY  - JOUR
AU  - Gray, J. W.
AU  - 
Collins, C.
TI  - Genome changes and gene expression
in human solid tumors
JA  - Carcinogenesis
PY  - 2000///
VL  - 21
SP  - 
443
EP  - 452
M3  - 10.1093/carcin/21.3.443
N1  - 10.1093/carcin/21.3.443
UR  - http://dx.doi.org/10.1093/carcin/21.3.443
ER  -

TY  - JOUR
AU  - Weinberg, R.
TI  - 
The cat and mouse games that genes, viruses, and cells play
JA  - Cell

PY  - 1997///
VL  - 88
SP  - 573
EP  - 575
M3  - 10.1016/S0092-8674(00)81897-8
N1  - 10.1016/S0092-8674(00)81897-8
UR  - http://dx.doi.org/10.1016/S0092-8674(00)81897-8
ER  -

TY  - JOUR
AU  - Turker, M. S.
TI  - 
Estimation of mutation frequencies in normal mammalian cells and the development
of cancer
JA  - Semin. Cancer Biol.
PY  - 1998///
VL  - 8
SP  - 407
EP  - 
419
M3  - 10.1006/scbi.1998.0112
N1  - 10.1006/scbi.1998.0112
UR  - http://dx.doi.org/10.1006/scbi.1998.0112
ER  -

TY  - JOUR
AU  - Dolle, M. E.
TI  - Rapid accumulation of genome rearrangements in liver but not
in brain of old mice
JA  - Nature Genet.
PY  - 1997///
VL  - 17
SP  - 
431
EP  - 434
M3  - 10.1038/ng1297-431
N1  - 10.1038/ng1297-431
UR  - http://dx.doi.org/10.1038/ng1297-431
ER  -

TY  - JOUR
AU  - Dolle, M. E.
AU  - 
Snyder, W. K.
AU  - Gossen, J.
A.
AU  - Lohman, P. H.
AU  - 
Vijg, J.
TI  - Distinct spectra of somatic mutations
accumulated with age in mouse heart and small intestine
JA  - Proc.
Natl Acad. Sci. USA
PY  - 2000///
VL  - 97
SP  - 8403
EP  - 8408
ER  -

TY  - GEN
AU  - Vijg, J.
AU  - 
Dolle, M. E. T.
TI  - Handbook of the Biology of
Ageing
ER  -

TY  - JOUR
AU  - Curtis, H.
AU  - 
Crowley, C.
TI  - Chromosome aberrations in liver
cells in relation to the somatic mutation theory of aging
JA  - Radiat.
Res.
PY  - 1963///
VL  - 19
SP  - 337
EP  - 344
ER  -

TY  - JOUR
AU  - Ly, D. H.
AU  - 
Lockhart, D. J.
AU  - Lerner, 
R. A.
AU  - Schultz, P. G.
TI  - 
Mitotic misregulation and human aging
JA  - Science
PY  - 2000///
VL  - 287
SP  - 
2486
EP  - 2492
M3  - 10.1126/science.287.5462.2486
N1  - 10.1126/science.287.5462.2486
UR  - http://dx.doi.org/10.1126/science.287.5462.2486
ER  -

TY  - JOUR
AU  - Ramsey, M. J.
TI  - The effects of age and lifestyle factors on the accumulation
of cytogenetic damage as measured by chromosome painting
JA  - Mutat.
Res.
PY  - 1995///
VL  - 338
SP  - 95
EP  - 106
ER  -

TY  - JOUR
AU  - Jacobs, P.
AU  - 
Brunton, M.
AU  - Brown, W.
AU  - 
Doll, R.
AU  - Goldstein, 
H.
TI  - Change of human chromosome count distributions with
age: evidence for a sex difference
JA  - Nature
PY  - 1963///
VL  - 197
SP  - 
1080
EP  - 1081
M3  - 10.1038/1971080a0
N1  - 10.1038/1971080a0
UR  - http://dx.doi.org/10.1038/1971080a0
ER  -

TY  - JOUR
AU  - Tucker, J. D.
AU  - 
Spruill, M. D.
AU  - Ramsey, M.
J.
AU  - Director, A. D.
AU  - 
Nath, J.
TI  - Frequency of spontaneous chromosome
aberrations in mice: effects of age
JA  - Mutat. Res.
PY  - 1999///
VL  - 425

SP  - 135
EP  - 141
M3  - 10.1016/S0027-5107(99)00036-6
N1  - 10.1016/S0027-5107(99)00036-6
UR  - http://dx.doi.org/10.1016/S0027-5107(99)00036-6
ER  -

TY  - JOUR
AU  - Moriwaki, S.
AU  - 
Ray, S.
AU  - Tarone, R. E.
AU  - 
Kraemer, K. H.
AU  - Grossman, 
L.
TI  - The effect of donor age on the processing of UV-damaged
DNA by cultured human cells: reduced DNA repair capacity and increased DNA
mutability
JA  - Mutat. Res.
PY  - 1996///
VL  - 364
SP  - 117
EP  - 
123
M3  - 10.1016/0921-8777(96)00029-8
N1  - 10.1016/0921-8777(96)00029-8
UR  - http://dx.doi.org/10.1016/0921-8777(96)00029-8
ER  -

TY  - JOUR
AU  - Goukassian, D.
TI  - Mechanisms and implications of the age-associated decrease
in DNA repair capacity
JA  - FASEB J.
PY  - 2000///
VL  - 14
SP  - 1325

EP  - 1334
M3  - 10.1096/fj.14.10.1325
N1  - 10.1096/fj.14.10.1325
UR  - http://dx.doi.org/10.1096/fj.14.10.1325
ER  -

TY  - JOUR
AU  - Liu, S. C.
AU  - 
Parsons, C. S.
AU  - Hanawalt, 
P. C.
TI  - DNA repair response in human epidermal keratinocytes
from donors of different age
JA  - J. Invest. Dermatol.
PY  - 1982///
VL  - 
79
SP  - 330
EP  - 335
ER  -

TY  - JOUR
AU  - Kolodner, R. D.
TI  - Germ-line msh6 mutations in colorectal cancer families
JA  - 
Cancer Res.
PY  - 1999///
VL  - 59
SP  - 5068
EP  - 5074
ER  -

TY  - JOUR
AU  - Baylin, S. B.
AU  - 
Herman, J. G.
TI  - DNA hypermethylation in tumorigenesis:
epigenetics joins genetics
JA  - Trends Genet.
PY  - 2000///
VL  - 16
SP  - 
168
EP  - 174
M3  - 10.1016/S0168-9525(99)01971-X
N1  - 10.1016/S0168-9525(99)01971-X
UR  - http://dx.doi.org/10.1016/S0168-9525(99)01971-X
ER  -

TY  - JOUR
AU  - Jones, P. A.
AU  - 
Laird, P. W.
TI  - Cancer epigenetics comes of age

JA  - Nature Genet.
PY  - 1999///
VL  - 21
SP  - 163
EP  - 
167
ER  -

TY  - JOUR
AU  - Issa, J. P.
TI  - Methylation of the oestrogen receptor CpG island links ageing
and neoplasia in human colon
JA  - Nature Genet.
PY  - 1994///
VL  - 7
SP  - 
536
EP  - 540
M3  - 10.1038/ng0894-536
N1  - 10.1038/ng0894-536
UR  - http://dx.doi.org/10.1038/ng0894-536
ER  -

TY  - JOUR
AU  - Issa, J. P.
TI  - 
Aging, DNA methylation and cancer
JA  - Crit. Rev. Oncol. Hematol.
PY  - 1999///
VL  - 
32
SP  - 31
EP  - 43
M3  - 10.1016/S1040-8428(99)00019-0
N1  - 10.1016/S1040-8428(99)00019-0
UR  - http://dx.doi.org/10.1016/S1040-8428(99)00019-0
ER  -

TY  - JOUR
AU  - Cormier, R. T.
AU  - Dove, W. F.
TI  - Dnmt1N/+ reduces
the net growth rate and multiplicity of intestinal adenomas in C57BL/6-multiple
intestinal neoplasia (Min)/+ mice independently of p53 but demonstrates strong
synergy with the modifier of Min 1(AKR) resistance allele
JA  - Cancer
Res.
PY  - 2000///
VL  - 60
SP  - 3965
EP  - 3970
ER  -

TY  - JOUR
AU  - Laird, P. W.
TI  - Suppression of intestinal neoplasia by DNA hypomethylation

JA  - Cell
PY  - 1995///
VL  - 81
SP  - 197
EP  - 205
M3  - 10.1016/0092-8674(95)90329-1
N1  - 10.1016/0092-8674(95)90329-1
UR  - http://dx.doi.org/10.1016/0092-8674(95)90329-1
ER  -

TY  - JOUR
AU  - Rhee, I.
TI  - CpG methylation is maintained in human cancer cells lacking DNMT1

JA  - Nature
PY  - 2000///
VL  - 404
SP  - 1003
EP  - 1007

M3  - 10.1038/35010000
N1  - 10.1038/35010000
UR  - http://dx.doi.org/10.1038/35010000
ER  -

TY  - JOUR
AU  - DePinho, R. A.
AU  - Sherr, C. J.
TI  - Cellular senescence:
mitotic clock or culture shock?
JA  - Cell
PY  - 2000///
VL  - 102
SP  - 
407
EP  - 410
M3  - 10.1016/S0092-8674(00)00046-5
N1  - 10.1016/S0092-8674(00)00046-5
UR  - http://dx.doi.org/10.1016/S0092-8674(00)00046-5
ER  -

TY  - JOUR
AU  - Atkin, N. B.
TI  - 
Solid tumor cytogenetics. Progress since 1979
JA  - Cancer Genet. Cytogenet.

PY  - 1989///
VL  - 40
SP  - 3
EP  - 12
M3  - 10.1016/0165-4608(89)90140-4
N1  - 10.1016/0165-4608(89)90140-4
UR  - http://dx.doi.org/10.1016/0165-4608(89)90140-4
ER  -

TY  - JOUR
AU  - Artandi, S. E.
TI  - Telomere dysfunction promotes non-reciprocal translocations
and epithelial cancers in mice
JA  - Nature
PY  - 2000///
VL  - 406
SP  - 
641
EP  - 645
M3  - 10.1038/35020592
N1  - 10.1038/35020592
UR  - http://dx.doi.org/10.1038/35020592
ER  -

TY  - JOUR
AU  - Greider, C.
TI  - 
Telomerase activity, cell proliferation, and cancer
JA  - Proc. Natl
Acad. Sci. USA
PY  - 1998///
VL  - 95
SP  - 90
ER  -

TY  - JOUR
AU  - Harley, C. B.
AU  - 
Futcher, A. B.
AU  - Greider, 
C. W.
TI  - Telomeres shorten during ageing of human fibroblasts

JA  - Nature
PY  - 1990///
VL  - 345
SP  - 458
EP  - 460
M3  - 10.1038/345458a0
N1  - 10.1038/345458a0
UR  - http://dx.doi.org/10.1038/345458a0
ER  -

TY  - JOUR
AU  - Hastie, N. D.
TI  - Telomere reduction in human colorectal carcinoma and with
ageing
JA  - Nature
PY  - 1990///
VL  - 346
SP  - 866
EP  - 
868
M3  - 10.1038/346866a0
N1  - 10.1038/346866a0
UR  - http://dx.doi.org/10.1038/346866a0
ER  -

TY  - JOUR
AU  - Allsopp, R. C.
TI  - Telomere length predicts replicative capacity of human fibroblasts

JA  - Proc. Natl Acad. Sci. USA
PY  - 1992///
VL  - 89
SP  - 10114
EP  - 
10118
ER  -

TY  - JOUR
AU  - Chadeneau, C.
AU  - 
Hay, K.
AU  - Hirte, H. W.
AU  - 
Gallinger, S.
AU  - Bacchetti, 
S.
TI  - Telomerase activity associated with acquisition of malignancy
in human colorectal cancer
JA  - Cancer Res.
PY  - 1995///
VL  - 55
SP  - 
2533
EP  - 2536
ER  -

TY  - JOUR
AU  - Kipling, D.
AU  - 
Cooke, H. J.
TI  - Hypervariable ultra-long telomeres
in mice
JA  - Nature
PY  - 1990///
VL  - 347
SP  - 400
EP  - 
402
M3  - 10.1038/347400a0
N1  - 10.1038/347400a0
UR  - http://dx.doi.org/10.1038/347400a0
ER  -

TY  - JOUR
AU  - Prowse, K. R.
AU  - 
Greider, C. W.
TI  - Developmental and tissue-specific
regulation of mouse telomerase and telomere length
JA  - Proc. Natl
Acad. Sci. USA
PY  - 1995///
VL  - 92
SP  - 4818
EP  - 4822
ER  -

TY  - JOUR
AU  - Broccoli, D.
AU  - 
Godley, L. A.
AU  - Donehower, 
L. A.
AU  - Varmus, H. E.
AU  - 
de, L. T.
TI  - Telomerase activation in mouse mammary
tumors: lack of detectable telomere shortening and evidence for regulation
of telomerase RNA with cell proliferation
JA  - Mol. Cell. Biol.
PY  - 1996///
VL  - 
16
SP  - 3765
EP  - 3772
ER  -

TY  - JOUR
AU  - Greenberg, R. A.
AU  - 
Allsopp, R. C.
AU  - Chin, L.
AU  - 
Morin, G. B.
AU  - DePinho, 
R. A.
TI  - Expression of mouse telomerase reverse transcriptase
during development, differentiation and proliferation
JA  - Oncogene

PY  - 1998///
VL  - 16
SP  - 1723
EP  - 1730
M3  - 10.1038/sj.onc.1201933
N1  - 10.1038/sj.onc.1201933
UR  - http://dx.doi.org/10.1038/sj.onc.1201933
ER  -

TY  - JOUR
AU  - Martin-Rivera, L.
AU  - 
Herrera, E.
AU  - Albar, J.
AU  - Blasco, M. A.
TI  - Expression of
mouse telomerase catalytic subunit in embryos and adult tissues
JA  - 
Proc. Natl Acad. Sci. USA
PY  - 1998///
VL  - 95
SP  - 10471
EP  - 
10476
M3  - 10.1073/pnas.95.18.10471
N1  - 10.1073/pnas.95.18.10471
UR  - http://dx.doi.org/10.1073/pnas.95.18.10471
ER  -

TY  - JOUR
AU  - Counter, C. M.
TI  - Telomere shortening associated with chromosome instability
is arrested in immortal cells which express telomerase activity
JA  - 
EMBO J.
PY  - 1992///
VL  - 11
SP  - 1921
EP  - 1929
ER  -

TY  - JOUR
AU  - McClintock, B.
TI  - 
The stability of broken ends of chromosomes in Zea mays
JA  - 
Genetics
PY  - 1941///
VL  - 26
SP  - 234
EP  - 282
ER  -

TY  - JOUR
AU  - Nishizaki, T.
TI  - Genetic alterations in primary breast cancers and their metastases:
direct comparison using modified comparative genomic hybridization
JA  - 
Genes Chromosomes Cancer
PY  - 1997///
VL  - 19
SP  - 267
EP  - 272

M3  - 10.1002/(SICI)1098-2264(199708)19:4<267::AID-GCC9>3.3.CO;2-U
N1  - 10.1002/(SICI)1098-2264(199708)19:4<267::AID-GCC9>3.3.CO;2-U
UR  - http://dx.doi.org/10.1002/(SICI)1098-2264(199708)19:4<267::AID-GCC9>3.3.CO;2-U
ER  -

TY  - JOUR
AU  - Buerger, H.
TI  - Comparative genomic hybridization of ductal carcinoma in situ
of the breast-evidence of multiple genetic pathways
JA  - J. Pathol.

PY  - 1999///
VL  - 187
SP  - 396
EP  - 402
M3  - 10.1002/(SICI)1096-9896(199903)187:4<396::AID-PATH286>3.0.CO;2-L
N1  - 10.1002/(SICI)1096-9896(199903)187:4<396::AID-PATH286>3.0.CO;2-L
UR  - http://dx.doi.org/10.1002/(SICI)1096-9896(199903)187:4<396::AID-PATH286>3.0.CO;2-L
ER  -

TY  - JOUR
AU  - Al-Mulla, F.
AU  - 
Keith, W. N.
AU  - Pickford, I.
R.
AU  - Going, J. J.
AU  - 
Birnie, G. D.
TI  - Comparative genomic hybridization
analysis of primary colorectal carcinomas and their synchronous metastases

JA  - Genes Chromosomes Cancer
PY  - 1999///
VL  - 24
SP  - 306
EP  - 
314
M3  - 10.1002/(SICI)1098-2264(199904)24:4<306::AID-GCC3>3.0.CO;2-5
N1  - 10.1002/(SICI)1098-2264(199904)24:4<306::AID-GCC3>3.0.CO;2-5
UR  - http://dx.doi.org/10.1002/(SICI)1098-2264(199904)24:4<306::AID-GCC3>3.0.CO;2-5
ER  -

TY  - JOUR
AU  - Tang, R.
AU  - 
Cheng, A. J.
AU  - Wang, J. Y.

AU  - Wang, T. C.
TI  - 
Close correlation between telomerase expression and adenomatous polyp progression
in multistep colorectal carcinogenesis
JA  - Cancer Res.
PY  - 1998///
VL  - 
58
SP  - 4052
EP  - 4054
ER  -

TY  - JOUR
AU  - Lee, H. W.
TI  - Essential role of mouse telomerase in highly proliferative
organs
JA  - Nature
PY  - 1998///
VL  - 392
SP  - 569
EP  - 
574
M3  - 10.1038/33345
N1  - 10.1038/33345
UR  - http://dx.doi.org/10.1038/33345
ER  -

TY  - JOUR
AU  - Rudolph, K. L.
TI  - Longevity, stress response, and cancer in aging telomerase-deficient
mice
JA  - Cell
PY  - 1999///
VL  - 96
SP  - 701
EP  - 712
M3  - 10.1016/S0092-8674(00)80580-2
N1  - 10.1016/S0092-8674(00)80580-2
UR  - http://dx.doi.org/10.1016/S0092-8674(00)80580-2
ER  -

TY  - JOUR
AU  - de Lange, T.
TI  - 
Activation of telomerase in a human tumor
JA  - Proc. Natl Acad. Sci.
USA
PY  - 1994///
VL  - 91
SP  - 2882
EP  - 2885
ER  -

TY  - JOUR
AU  - Foley, K. P.
AU  - 
Eisenman, R. N.
TI  - Two MAD tails: what the recent
knockouts of Mad1 and Mxi1 tell us about the MYC/MAX/MAD network
JA  - 
Biochim. Biophys. Acta
PY  - 1999///
VL  - 1423
SP  - M37
EP  - M47

M3  - 10.1016/S0304-419X(99)00012-8
N1  - 10.1016/S0304-419X(99)00012-8
UR  - http://dx.doi.org/10.1016/S0304-419X(99)00012-8
ER  -

TY  - JOUR
AU  - Rudolph, K. L.
AU  - 
Chang, S.
AU  - Millard, M.
AU  - 
Schreiber-Agus, N.
AU  - DePinho, 
R. A.
TI  - Inhibition of experimental liver cirrhosis in mice
by telomerase gene delivery
JA  - Science
PY  - 2000///
VL  - 287
SP  - 
1253
EP  - 1258
M3  - 10.1126/science.287.5456.1253
N1  - 10.1126/science.287.5456.1253
UR  - http://dx.doi.org/10.1126/science.287.5456.1253
ER  -

TY  - JOUR
AU  - Kitada, T.
AU  - 
Seki, S.
AU  - Kawakita, N.
AU  - 
Kuroki, T.
AU  - Monna, T.

TI  - Telomere shortening in chronic liver diseases
JA  - 
Biochem. Biophys. Res. Commun.
PY  - 1995///
VL  - 211
SP  - 33
EP  - 
39
M3  - 10.1006/bbrc.1995.1774
N1  - 10.1006/bbrc.1995.1774
UR  - http://dx.doi.org/10.1006/bbrc.1995.1774
ER  -

TY  - JOUR
AU  - Miura, N.
TI  - Progressive telomere shortening and telomerase reactivation during
hepatocellular carcinogenesis
JA  - Cancer Genet. Cytogenet.
PY  - 1997///
VL  - 
93
SP  - 56
EP  - 62
M3  - 10.1016/S0165-4608(96)00329-9
N1  - 10.1016/S0165-4608(96)00329-9
UR  - http://dx.doi.org/10.1016/S0165-4608(96)00329-9
ER  -

TY  - JOUR
AU  - Urabe, Y.
TI  - Telomere length in human liver diseases
JA  - Liver
PY  - 1996///
VL  - 
16
SP  - 293
EP  - 297
ER  -

TY  - JOUR
AU  - Weinberg, R. A.
TI  - 
The retinoblastoma protein and cell cycle control
JA  - Cell
PY  - 1995///
VL  - 
81
SP  - 323
EP  - 330
M3  - 10.1016/0092-8674(95)90385-2
N1  - 10.1016/0092-8674(95)90385-2
UR  - http://dx.doi.org/10.1016/0092-8674(95)90385-2
ER  -

TY  - JOUR
AU  - Debbas, M.
AU  - 
White, E.
TI  - Wild-type p53 mediates apoptosis by
E1A, which is inhibited by E1B
JA  - Genes Dev.
PY  - 1993///
VL  - 7
SP  - 
546
EP  - 554
M3  - 10.1101/gad.7.4.546
N1  - 10.1101/gad.7.4.546
UR  - http://dx.doi.org/10.1101/gad.7.4.546
ER  -

TY  - JOUR
AU  - Symonds, H.
TI  - p53-dependent apoptosis suppresses tumor growth and progression
in vivo
JA  - Cell
PY  - 1994///
VL  - 78
SP  - 703
EP  - 711

M3  - 10.1016/0092-8674(94)90534-7
N1  - 10.1016/0092-8674(94)90534-7
UR  - http://dx.doi.org/10.1016/0092-8674(94)90534-7
ER  -

TY  - JOUR
AU  - Morgenbesser, S. D.
AU  - 
Williams, B. O.
AU  - Jacks, T.

AU  - DePinho, R. A.
TI  - 
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse
lens
JA  - Nature
PY  - 1994///
VL  - 371
SP  - 72
EP  - 74

M3  - 10.1038/371072a0
N1  - 10.1038/371072a0
UR  - http://dx.doi.org/10.1038/371072a0
ER  -

TY  - JOUR
AU  - Kim, N. W.
TI  - Specific association of human telomerase activity with immortal
cells and cancer
JA  - Science
PY  - 1994///
VL  - 266
SP  - 2011
EP  - 
2015
ER  -

TY  - JOUR
AU  - Blasco, M. A.
AU  - 
Rizen, M.
AU  - Greider, C. W.

AU  - Hanahan, D.
TI  - 
Differential regulation of telomerase activity and telomerase RNA during multi-stage
tumorigenesis
JA  - Nature Genet.
PY  - 1996///
VL  - 12
SP  - 200
EP  - 
204
M3  - 10.1038/ng0296-200
N1  - 10.1038/ng0296-200
UR  - http://dx.doi.org/10.1038/ng0296-200
ER  -

TY  - JOUR
AU  - Greenberg, R. A.
TI  - Short dysfunctional telomeres impair tumorigenesis in the
INK4a([Delta]2/3) cancer-prone mouse
JA  - Cell
PY  - 1999///
VL  - 97
SP  - 
515
EP  - 525
M3  - 10.1016/S0092-8674(00)80761-8
N1  - 10.1016/S0092-8674(00)80761-8
UR  - http://dx.doi.org/10.1016/S0092-8674(00)80761-8
ER  -

TY  - JOUR
AU  - Hahn, W. C.
TI  - Creation of human tumour cells with defined genetic elements

JA  - Nature
PY  - 1999///
VL  - 400
SP  - 464
EP  - 468
M3  - 10.1038/22780
N1  - 10.1038/22780
UR  - http://dx.doi.org/10.1038/22780
ER  -

TY  - JOUR
AU  - Chin, L.
AU  - 
DePinho, R. A.
TI  - Flipping the oncogene switch:
illumination of tumor maintenance and regression
JA  - Trends Genet.

PY  - 2000///
VL  - 16
SP  - 147
EP  - 150
M3  - 10.1016/S0168-9525(99)01968-X
N1  - 10.1016/S0168-9525(99)01968-X
UR  - http://dx.doi.org/10.1016/S0168-9525(99)01968-X
ER  -

TY  - JOUR
AU  - Chin, L.
TI  - Essential role for oncogenic RAS in tumour maintenance
JA  - 
Nature
PY  - 1999///
VL  - 400
SP  - 468
EP  - 472
M3  - 10.1038/22788
N1  - 10.1038/22788
UR  - http://dx.doi.org/10.1038/22788
ER  -

TY  - JOUR
AU  - Pelengaris, S.
AU  - 
Littlewood, T.
AU  - Khan, M.
AU  - 
Elia, G.
AU  - Evan, G.
TI  - 
Reversible activation of c-Myc in skin: induction of a complex neoplastic
phenotype by a single oncogenic lesion
JA  - Mol. Cell
PY  - 1999///
VL  - 3

SP  - 565
EP  - 577
M3  - 10.1016/S1097-2765(00)80350-0
N1  - 10.1016/S1097-2765(00)80350-0
UR  - http://dx.doi.org/10.1016/S1097-2765(00)80350-0
ER  -

TY  - JOUR
AU  - Gelman, R.
AU  - 
Watson, A.
AU  - Bronson, R.
AU  - Yunis, E.
TI  - Murine chromosomal
regions correlated with longevity
JA  - Genetics
PY  - 1988///
VL  - 118
SP  - 
693
EP  - 704
ER  -

TY  - JOUR
AU  - Cunha, G.
AU  - 
Hom, Y.
TI  - Role of mesenchymal-epithelial interactions
in mammary gland development
JA  - J. Mamm. Gland Biol. Neoplasia
PY  - 1996///
VL  - 
1
SP  - 21
EP  - 35
ER  -

TY  - JOUR
AU  - Olumi, A. F.
TI  - Carcinoma-associated fibroblasts direct tumor progression
of initiated human prostatic epithelium
JA  - Cancer Res.
PY  - 1999///
VL  - 
59
SP  - 5002
EP  - 5011
ER  -

TY  - JOUR
AU  - Dimri, G. P.
TI  - A biomarker that identifies senescent human cells in culture
and in aging skin in vivo
JA  - Proc. Natl Acad. Sci. USA
PY  - 1995///
VL  - 
92
SP  - 9363
EP  - 9367
ER  -

TY  - JOUR
AU  - Shelton, D. N.
AU  - 
Chang, E.
AU  - Whittier, P. S.

AU  - Choi, D.
AU  - 
Funk, W. D.
TI  - Microarray analysis of replicative
senescence
JA  - Curr. Biol.
PY  - 1999///
VL  - 9
SP  - 939
EP  - 
945
M3  - 10.1016/S0960-9822(99)80420-5
N1  - 10.1016/S0960-9822(99)80420-5
UR  - http://dx.doi.org/10.1016/S0960-9822(99)80420-5
ER  -

TY  - JOUR
AU  - Campisi, J.
TI  - 
Aging and cancer: the double-edged sword of replicative senescence
JA  - 
J. Am. Geriatr. Soc.
PY  - 1997///
VL  - 45
SP  - 482
EP  - 488
ER  -

TY  - JOUR
AU  - Serrano, M.
AU  - 
Lin, A. W.
AU  - McCurrach, M.
E.
AU  - Beach, D.
AU  - 
Lowe, S. W.
TI  - Oncogenic ras provokes premature
cell senescence associated with accumulation of p53 and p16INK4a
JA  - 
Cell
PY  - 1997///
VL  - 88
SP  - 593
EP  - 602
M3  - 10.1016/S0092-8674(00)81902-9
N1  - 10.1016/S0092-8674(00)81902-9
UR  - http://dx.doi.org/10.1016/S0092-8674(00)81902-9
ER  -

TY  - JOUR
AU  - Di Leonardo, A.
AU  - 
Linke, S. P.
AU  - Clarkin, K.

AU  - Wahl, G. M.
TI  - 
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction
of Cip1 in normal human fibroblasts
JA  - Genes Dev.
PY  - 1994///
VL  - 8
SP  - 
2540
EP  - 2551
M3  - 10.1101/gad.8.21.2540
N1  - 10.1101/gad.8.21.2540
UR  - http://dx.doi.org/10.1101/gad.8.21.2540
ER  -

TY  - JOUR
AU  - Coussens, L. M.
TI  - Inflammatory mast cells up-regulate angiogenesis during squamous
epithelial carcinogenesis
JA  - Genes Dev.
PY  - 1999///
VL  - 13
SP  - 
1382
EP  - 1397
M3  - 10.1101/gad.13.11.1382
N1  - 10.1101/gad.13.11.1382
UR  - http://dx.doi.org/10.1101/gad.13.11.1382
ER  -

TY  - JOUR
AU  - Bergers, G.
TI  - Matrix metalloprotein-9 triggers the angiogenic switch during
carcinogenesis
JA  - Nature Cell Biol.
PY  - 2000///
VL  - 2
SP  - 737

EP  - 744
ER  -

TY  - JOUR
AU  - Coussens, L.
AU  - 
Tinkle, C.
AU  - Hanahan, D.
AU  - Werb, Z.
TI  - MMP-9 supplied by
bone marrow-derived cells contributes to skin carcinogenesis
JA  - 
Cell
ER  -

TY  - JOUR
AU  - Millis, A. J.
AU  - 
Hoyle, M.
AU  - McCue, H. M.
AU  - Martini, H.
TI  - Differential expression
of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged
human fibroblasts
JA  - Exp. Cell Res.
PY  - 1992///
VL  - 201
SP  - 373

EP  - 379
M3  - 10.1016/0014-4827(92)90286-H
N1  - 10.1016/0014-4827(92)90286-H
UR  - http://dx.doi.org/10.1016/0014-4827(92)90286-H
ER  -

TY  - JOUR
AU  - Sternlicht, M. D.
TI  - The stromal proteinase MMP3/stromelysin-1 promotes mammary
carcinogenesis
JA  - Cell
PY  - 1999///
VL  - 98
SP  - 137
EP  - 
146
M3  - 10.1016/S0092-8674(00)81009-0
N1  - 10.1016/S0092-8674(00)81009-0
UR  - http://dx.doi.org/10.1016/S0092-8674(00)81009-0
ER  -

TY  - JOUR
AU  - Robertson, K. D.
AU  - Jones, P. A.
TI  - DNA methylation:
past, present and future directions
JA  - Carcinogenesis
PY  - 2000///
VL  - 
21
SP  - 461
EP  - 467
M3  - 10.1093/carcin/21.3.461
N1  - 10.1093/carcin/21.3.461
UR  - http://dx.doi.org/10.1093/carcin/21.3.461
ER  -

TY  - JOUR
AU  - Piantanelli, L.
TI  - 
Cancer and aging: from the kinetics of biological parameters to the kinetics
of cancer incidence and mortality
JA  - Ann. NY Acad. Sci.
PY  - 1988///
VL  - 
521
SP  - 99
EP  - 109
ER  -

TY  - JOUR
AU  - Schwartz, R. A.
TI  - 
JA  - 
Skin Cancer: Recognition and Management
PY  - 1988///
ER  -
