Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 408, 255-262 (9 November 2000) | doi:10.1038/35041700
Open Innovation Challenges
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
- More Challenges
- Powered by:
nature jobs
Laboratory Technician (Pharmaceutics)
- Alliance Institute of Advanced Pharmacy and Health Sciences
- Hyderabad 500038 India
Professor of Psychosomatic Medicine (W2)
- The University Hospital Jena, Institute of Psychosocial Medicine and Psychotherapy
- Jena Germany
review article Genetic pathways that regulate ageing in model organisms
Leonard Guarente1 & Cynthia Kenyon2
Abstract
Searches for genes involved in the ageing process have been made in genetically tractable model organisms such as yeast, the nematode Caenorhabditis elegans , Drosophila melanogaster fruitflies and mice. These genetic studies have established that ageing is indeed regulated by specific genes, and have allowed an analysis of the pathways involved, linking physiology, signal transduction and gene regulation. Intriguing similarities in the phenotypes of many of these mutants indicate that the mutations may also perturb regulatory systems that control ageing in higher organisms.
To read this story in full you will need to login or make a payment (see right).
