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Correspondence
Nature 408, 17 (2 November 2000) | doi:10.1038/35040756
Results may not fit well with current theories . . .
Gabby Dover1
- Department of Genetics, University of Leicester, University Road, Leicester LE1 7RH, UK
There is a narrow inevitability about Partridge and Barton's response1 to True and Lindquist's evolutionary interpretation of their remarkable finding: that the presence of the yeast prion [PSI+] releases cryptic phenotypic variation which allows cells to thrive in fluctuating environments and which may facilitate the establishment of new traits2.Partridge and Barton hover between dismissal and marginalization — the last resting place of many new discoveries of genome and developmental dynamics that do not fit easily with the simplistic notion of so-called 'modern' Darwinism that DNA mutation and recombination are the sole heritable changes of state of concern to selection.
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