FIGURE 3. Prolonged activity for the stem cell population in raf-deficient testes.

From the following article:

Somatic control over the germline stem cell lineage during Drosophila spermatogenesis

John Tran, Tamara J. Brenner and Stephen DiNardo

Nature 407, 754-757(12 October 2000)

doi:10.1038/35037613

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a, WT testis, X-gal activity; M5-4 expressed in the hub (arrowhead), germline stem cells (large arrow), and gonialblasts (smaller arrow). b , raf-deficient testis; M5-4 is expressed in many cells near hub (arrowhead). c, WT testis, day 19; expression solely in hub. d, raf-deficient testis, day 19. e, WT testis, day 19; branched fusomes (green) are visible further along the testis (arrow), but there are no cells with spherical fusomes adjacent to hub (arrowhead). f, raf-deficient testis, day 19; an example of late-interphase (nuclear Anillin, red) germline stem cell (arrow), as indicated by the presence of a spherical fusome (green) in the cell adjacent to the hub (arrowhead). Scale bar, 40 microm.

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