Table of contents


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Opinion

What hopes for GM food? p431

The industry based on genetic modification of plants has suffered new setbacks. Europe's public is at the least sceptical, but still potentially accepting, of GM crops, provided progress in technology, regulation and communication is maintained.

doi:10.1038/35035224


Triumph, but self-criticism too p431

The release of an alleged spy at the Los Alamos laboratory comes none too soon, but prompts other questions.

doi:10.1038/35035226


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News

Europe urged to set up advisory body on research infrastructure p433

Quirin Schiermeier

doi:10.1038/35035228


Canadian science told to look north p433

David Spurgeon

doi:10.1038/35035232


UK faces rethink on AIDS treatment p434

Karen Birmingham

doi:10.1038/35035234


NSF aims to inject more maths into biology p435

Rex Dalton

doi:10.1038/35035237


France backs IT and life sciences p435

Declan Butler

doi:10.1038/35035241


Disagreements derail US bill to double research funding... p436

Colin Macilwain

doi:10.1038/35035244


...as physical sciences plan lobbying body p436

Colin Macilwain

doi:10.1038/35035246


Antibiotic resistance must be monitored, US Senate is told p437

Paul Smaglik

doi:10.1038/35035249


Report praises European radio telescope network p437

Alison Abbott

doi:10.1038/35035251


News in brief p438

doi:10.1038/35035254


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News Feature

A springboard to success p440

Can Brazil build on its achievement of completing the first genome sequence of a plant pathogen? That may depend on its willingness to reform its universities, say Colin Macilwain and Ricardo Bonalume Neto.

Colin Macilwain and Ricardo Bonalume Neto

doi:10.1038/35035207


Cheap and cheerful circuits p442

Silicon remains the computer chip industry's material of choice. But for simpler circuitry, it could soon have some surprising rivals. David Voss talks to the scientists who are trying to make electronics go organic.

David Voss

doi:10.1038/35035212


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Correspondence

Don't dismiss chlorine; it could help us to avoid the fate of the Romans p445

Ferdinand Engelbeen

doi:10.1038/35035257


Bright future in the stars for big telescopes? p445

P. R. Jewell, F. J. Lockman and T. M. Bania

doi:10.1038/35035259


Non-scientists thanked for vital help in Kansas p445

Matthew Buechner

doi:10.1038/35035261


erratum: England and the US corner the journal market p445

A.A. Waheed

doi:10.1038/35035263


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Commentary

Science-based security under threat p447

Los Alamos National Laboratory is an endangered national treasure.

doi:10.1038/35035219


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Book Reviews

Taking the heat out of global warming p449

Two 'mainstream sceptics' take a critical look at the majority view.

Hans von Storch reviews The Satanic Gases: Clearing the Air about Global Warming by Patrick J. Michaels and Robert C. Balling

doi:10.1038/35035140


On an industrial footing p449

doi:10.1038/35035142


Man made machine? p450

doi:10.1038/35035145


To the core of consciousness p450

Raymond J. Dolan reviews A Universe of Consciousness: How Matter Becomes Imagination/ Consciousness: How Matter Becomes Imagination by Gerald Edelman and Giulio Tononi

doi:10.1038/35035148


A dip in the soup, with a pinch of salt p451

William J. Hagan reviews The Spark of Life: Darwin and the Primeval Soup by Christopher Wills and Jeffrey Bada

doi:10.1038/35035150


Pitfalls, blind alleys and much more p452

Sam Glucksberg reviews Through the Rearview Mirror: Historical Reflections on Psychology by John Macnamara

doi:10.1038/35035153


Top

Millennium Essay

An electromagnetic personality p453

An Elizabethan experimentalist and spirited foe of pseudoscience.

James D. Livingston

doi:10.1038/35035167


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Futures

Through the shaving mirror p455

...or, A tight night at the Surrealist Sporting Club.

Michael Moorcock and Maurice Richardson

doi:10.1038/35035170


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News and Views

Natural Selection: Evolving evolvability p457

In yeast, a modified protein known as a prion generates variation in growth rate across diverse environments. Is this an example of an agent that has evolved in order to promote its possessor's adaptability?

Linda Partridge and Nicholas H. Barton

doi:10.1038/35035173


Geochemistry: Hot heads and cold tails p458

Nicholas Arndt

doi:10.1038/35035176


100 and 50 years ago p459

doi:10.1038/35035179


Molecular physiology: Globins in the brain p461

Luc Moens and Sylvia Dewilde

doi:10.1038/35035181


Conservation biology: Ducks and darkes p461

Chris Mead

doi:10.1038/35035183


Optical astronomy: The resolution revolution p462

Tyler Nordgren

doi:10.1038/35035186


Translation: The twenty-first amino acid p463

John F. Atkins and Raymond F. Gesteland

doi:10.1038/35035189


Statistical physics: Following the crowd p465

David J. Low

doi:10.1038/35035192


Genomics: Use your neighbour's genes p466

Don Cowan

doi:10.1038/35035195


correction: Plankton cooled a greenhouse p467

Birger Schmitz

doi:10.1038/35035198


Daedalus: Talking to animals p467

David Jones

doi:10.1038/35035200


correction: Feedback on Gaia p467

Jim Gillon

doi:10.1038/35035205


Obituary: Mark Oliphant (1901–2000) p468

Joseph Rotblat

doi:10.1038/35035202


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Brief Communications

Maternal age and traits in offspring p469

The timing of a mouse's first litter influences the development of her pups.

Ming-Hseng Wang and Frederick S. vom Saal

doi:10.1038/35035156


Intelligence: Maze-solving by an amoeboid organism p470

Toshiyuki Nakagaki, Hiroyasu Yamada and Ágota Tóth

doi:10.1038/35035159


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Review

RNA polymerase II elongation through chromatin p471

George Orphanides and Danny Reinberg

doi:10.1038/35035000


Top

Article

A yeast prion provides a mechanism for genetic variation and phenotypic diversity p477

Heather L. True and Susan L. Lindquist

doi:10.1038/35035005

See also: News and Views by Partridge & Barton


Top

Letters to Nature

Direct detection of pulsations of the Cepheid star zeta Gem and an independent calibration of the period–luminosity relation p485

B. F. Lane, M. J. Kuchner, A. F. Boden, M. Creech-Eakman and S. R. Kulkarni

doi:10.1038/35035015

See also: News and Views by Nordgren


Simulating dynamical features of escape panic p487

Dirk Helbing, Illés Farkas and Tamás Vicsek

doi:10.1038/35035023

See also: News and Views by Low


Single photons on demand from a single molecule at room temperature p491

B. Lounis and W. E. Moerner

doi:10.1038/35035032


Logical computation using algorithmic self-assembly of DNA triple-crossover molecules p493

Chengde Mao, Thomas H. LaBean, John H. Reif and Nadrian C. Seeman

doi:10.1038/35035038


Nano-sized transition-metal oxides as negative-electrode materials for lithium-ion batteries p496

P. Poizot, S. Laruelle, S. Grugeon, L. Dupont and J-M. Tarascon

doi:10.1038/35035045


Origins of sulphate in Antarctic dry-valley soils as deduced from anomalous 17O compositions p499

Huiming Bao, Douglas A. Campbell, James G. Bockheim and Mark H. Thiemens

doi:10.1038/35035054


Transient high temperatures in mantle plume heads inferred from magnesian olivines in Phanerozoic picrites p502

R. N. Thompson and S. A. Gibson

doi:10.1038/35035058

See also: News and Views by Arndt


Evolutionary instability of ectomycorrhizal symbioses in basidiomycetes p506

David S. Hibbett, Luz-Beatriz Gilbert and Michael J. Donoghue

doi:10.1038/35035065


The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum p508

Andreas Ruepp, Werner Graml, Martha-Leticia Santos-Martinez, Kristin K. Koretke, Craig Volker, H. Werner Mewes, Dmitrij Frishman, Susanne Stocker, Andrei N. Lupas and Wolfgang Baumeister

doi:10.1038/35035069

See also: News and Views by Cowan


An SNP map of the human genome generated by reduced representation shotgun sequencing p513

David Altshuler, Victor J. Pollara, Chris R. Cowles, William J. Van Etten, Jennifer Baldwin, Lauren Linton and Eric S. Lander

doi:10.1038/35035083


An SNP map of human chromosome 22 p516

J. C. Mullikin, S. E. Hunt, C. G. Cole, B. J. Mortimore, C. M. Rice, J. Burton, L. H. Matthews, R. Pavitt, R. W. Plumb, S. K. Sims, R. M. R. Ainscough, J. Attwood, J. M. Bailey, K. Barlow, R. M. M. Bruskiewich, P. N. Butcher, N. P. Carter, Y. Chen, C. M. Clee, P. C. Coggill, J. Davies, R. M. Davies, E. Dawson, M. D. Francis, A. A. Joy, R. G. Lamble, C. F. Langford, J. Macarthy, V. Mall, A. Moreland, E. K. Overton-Larty, M. T. Ross, L. C. Smith, C. A. Steward, J. E. Sulston, E. J. Tinsley, K. J. Turney, D. L. Willey, G. D. Wilson, A. A. McMurray, I. Dunham, J. Rogers and D. R. Bentley

doi:10.1038/35035089


A vertebrate globin expressed in the brain p520

Thorsten Burmester, Bettina Weich, Sigrid Reinhardt and Thomas Hankeln

doi:10.1038/35035093

See also: News and Views by Moens & Dewilde


Immune control of HIV-1 after early treatment of acute infection p523

Eric S. Rosenberg, Marcus Altfeld, Samuel H. Poon, Mary N. Phillips, Barbara M. Wilkes, Robert L. Eldridge, Gregory K. Robbins, Richard T. D'Aquila, Philip J. R. Goulder and Bruce D. Walker

doi:10.1038/35035103


arrow encodes an LDL-receptor-related protein essential for Wingless signalling p527

Marcel Wehrli, Scott T. Dougan, Kim Caldwell, Louise O'Keefe, Stephanie Schwartz, Dalit Vaizel-Ohayon, Eyal Schejter, Andrew Tomlinson and Stephen DiNardo

doi:10.1038/35035110


LDL-receptor-related proteins in Wnt signal transduction p530

Keiko Tamai, Mikhail Semenov, Yoichi Kato, Rebecca Spokony, Chunming Liu, Yu Katsuyama, Fred Hess, Jean-Pierre Saint-Jeannet and Xi He

doi:10.1038/35035117


An LDL-receptor-related protein mediates Wnt signalling in mice p535

Kathleen I. Pinson, Jane Brennan, Susan Monkley, Brian J. Avery and William C. Skarnes

doi:10.1038/35035124


Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase p538

Tommaso Simoncini, Ali Hafezi-Moghadam, Derek P. Brazil, Klaus Ley, William W. Chin and James K. Liao

doi:10.1038/35035131


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New on the Market

Genes, chains and rats p543

Gene expression, quicker PCR and rodent observation in this week's haul.

doi:10.1038/35035163


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