Table of contents
Volume 407 Number 6802 pp273-430
Opinion
Bridging the Taiwan Strait p273
The political and practical obstacles to greater scientific exchange between Taiwan and the Chinese mainland are significant. It is achievable, however, and is in the best interests of both parties.
doi:10.1038/35030361
Reviews for reviews' sake p273
Next month sees three new Nature review titles that make the most of the partnership between editors and authors.
doi:10.1038/35030363
News
Doubts grow over discovery of fossilized 'dinosaur heart' p275
Rex Dalton
doi:10.1038/35030365
UK advised to step up asteroid hunt p275
Natasha Loder
doi:10.1038/35030368
Hunt for Higgs particle wins time for CERN collider p276
Alison Abbott
doi:10.1038/35030370
World Bank is urged to give greater priority to science p276
Colin Macilwain
doi:10.1038/35030373
European space panel picks new priorities p277
Alison Abbott
doi:10.1038/35030376
NASA reaches out to universities p277
William Triplett
doi:10.1038/35030379
Case of the stolen Enigma machine takes cryptic turn p278
Natasha Loder
doi:10.1038/35030382
Germline gene therapy needs tight control, says US panel p278
Paul Smaglik
doi:10.1038/35030385
Japan opens access to mouse cDNA data... p279
David Cyranoski
doi:10.1038/35030387
...and to report on strengths and weaknesses of genomics centre p279
David Cyranoski
doi:10.1038/35030390
News Feature
A chemistry set for life p282
Small molecules that selectively disrupt the proteins encoded by individual genes could become powerful tools in functional genomics. Trisha Gura explores the nascent but highly promising field of chemical genetics.
Trisha Gura
doi:10.1038/35030189
Correspondence
Allowing gene patents could be an expensive mistake for the US p285
Hartmut Michel
doi:10.1038/35030194
No room on the carousel for meeting of like minds p285
Eleuterio R. Hernandez
doi:10.1038/35030196
Standardized addresses would make web easier p285
Sasidharan Rajkumar
doi:10.1038/35030198
The Durban Declaration is not accepted by all p286
Gordon T. Stewart MD
doi:10.1038/35030200
Sky was not the limit for music-loving Herschel p286
Martin F. Heyworth
doi:10.1038/35030202
Commentary
Good and bad science in US schools p287
One-third of US states have unsatisfactory standards for teaching evolution.
doi:10.1038/35030204
New Journals
Is your journal really necessary? p291
Science may best prosper if print journals are replaced by online communities.
Declan Butler reviews
doi:10.1038/35030209
Healing in the genes p292
Karin Sitte and Robert Williamson review Molecular Therapy (American Society of Gene Therapy) and The Journal of Gene Medicine (European Society of Gene Therapy) and Genetics in Medicine
doi:10.1038/35030211
Reborn for a new era p292
Rudi Balling reviews Genesis: The Journal of Genetics and Development
doi:10.1038/35030214
Psychic secretions p293
John C. Marshall reviews The International Journal of Neuropsychopharmacology
doi:10.1038/35030217
Problems of a glandular nature p293
Stafford L. Lightman reviews Pituitary
doi:10.1038/35030220
The art of the saveable p294
William J. Sutherland reviews Animal Conservation
doi:10.1038/35030222
Strong growth in the environmental field p294
Graham Wood reviews Journal of Environmental Monitoring and Journal of Environmental Policy & Planning
doi:10.1038/35030225
More than a breath of fresh air p295
Ian Fells reviews Wind Energy
doi:10.1038/35030227
Chemists exploring a verdant field p295
Walter Leitner reviews Green Chemistry
doi:10.1038/35030230
Chemistry's voice heard at last p296
Bernadette Bensaude-Vincent reviews Foundations of Chemistry: Philosophical, Historical, Educational and Interdisciplinary Studies of Chemistry
doi:10.1038/35030233
Struggling with complexity p296
Gastone Gilli reviews Crystal Engineering
doi:10.1038/35030235
Across the boundaries p297
Albert-László Barabási reviews Interfaces and Free Boundaries: Modeling, Analysis and Computation
doi:10.1038/35030238
Europe's hard forum for soft matter p297
Steve Granick and Sung Chul Bae review The European Physical Journal E — Soft Matter
doi:10.1038/35030240
Making way for complex issues p297
William Ditto reviews Nonlinear Phenomena in Complex Systems
doi:10.1038/35030242
Backing the n-word p298
Saul Tendler reviews Journal of Nanoparticle Research
doi:10.1038/35030245
Plant power against pollution p298
William Purvis reviews International Journal of Phytoremediation
doi:10.1038/35030247
Green and red lights at the cell p299
Reinhard Jahn reviews Traffic: The International Journal of Intracellular Transport
doi:10.1038/35030250
The nidus and the crucible p299
Moya Meredith Smith reviews Evolution & Development
doi:10.1038/35030252
Crossing the resistance divide p300
Eric J. Arts reviews Drug Resistance Updates
doi:10.1038/35030255
Also submitted p300
doi:10.1038/35030258
Millennium Essay
Down to earth p301
Why soil — and soil science — matters.
Dan H. Yaalon
doi:10.1038/35030260
Futures
The Great Goodbye p303
The emotional cost of the post-evolutionary divide.
Robert Charles Wilson
doi:10.1038/35030263
News and Views
Materials Science: A moving oxygen story p305
Titanium is one of the most versatile materials used in engineering. An innovative way of producing it from titanium dioxide will make the metal cheaper — if the process can be scaled up.
Harvey M. Flower
doi:10.1038/35030266
100 and 50 years ago p306
doi:10.1038/35030269
Molecular biology: Small subunit, big science p306
James R. Williamson
doi:10.1038/35030271
Astronomy: Galactic rotation in real time p307
John Kormendy
doi:10.1038/35030274
Cancer: A radical approach to treatment p309
John L. Cleveland and Michael B. Kastan
doi:10.1038/35030277
Ocean biogeochemistry: Calcification and CO2 p311
Jean-Pierre Gattuso and Robert W. Buddemeier
doi:10.1038/35030280
AIDS: Escape from the immune system p313
Bruce D. Walker and Philip J. R. Goulder
doi:10.1038/35030283
Developmental biology: Post-expressionist flies p314
Sarah Bray and David Stein
doi:10.1038/35030286
Daedalus: The sound of silence p315
David Jones
doi:10.1038/35030289
Obituary: Elvin A. Kabat (1914–2000) p316
William E. Paul and Rose G. Mage
doi:10.1038/35030291
Brief Communications
Membrane changes during hibernation p317
Organelle lipids undergo rapidly reversible rearrangement as body temperature drops.
Nabil A. Azzam, John M. Hallenbeck and Bechara Kachar
doi:10.1038/35030294
First paragraph | Full Text | PDF (302K)
Metabolism: Winter torpor in a large bird p318
Gerhard Körtner, R. Mark Brigham and Fritz Geiser
doi:10.1038/35030297
First paragraph | Full Text | PDF (413K)
Ageing: Cloning of mice to six generations p318
Teruhiko Wakayama, Yoichi Shinkai, Kellie L. K. Tamashiro, Hiroyuki Niida, D. Caroline Blanchard, Robert J. Blanchard, Atsuo Ogura, Kentaro Tanemura, Makoto Tachibana, Anthony C. F. Perry, Diana F. Colgan, Peter Mombaerts and Ryuzo Yanagimachi
doi:10.1038/35030301
First paragraph | Full Text | PDF (413K)
Gene expression: Total silencing by intron-spliced hairpin RNAs p319
Neil A. Smith, Surinder P. Singh, Ming-Bo Wang, Peter A. Stoutjesdijk, Allan G. Green and Peter M. Waterhouse
doi:10.1038/35030305
First paragraph | Full Text | PDF (310K)
Review
Loosening of plant cell walls by expansins p321
Daniel J. Cosgrove
doi:10.1038/35030000
Abstract | Full Text | PDF (528K)
Articles
Structure of the 30S ribosomal subunit p327
Brian T. Wimberly, Ditlev E. Brodersen, William M. Clemons, Jr, Robert J. Morgan-Warren, Andrew P. Carter, Clemens Vonrhein, Thomas Hartsch and V. Ramakrishnan
doi:10.1038/35030006
Abstract | Full Text | PDF (1,698K)
See also: News and Views by Williamson
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics p340
Andrew P. Carter, William M. Clemons, Ditlev E. Brodersen, Robert J. Morgan-Warren, Brian T. Wimberly and V. Ramakrishnan
doi:10.1038/35030019
Abstract | Full Text | PDF (989K) | Supplementary information
See also: News and Views by Williamson
Letters to Nature
The accelerations of stars orbiting the Milky Way's central black hole p349
A. M. Ghez, M. Morris, E. E. Becklin, A. Tanner and T. Kremenek
doi:10.1038/35030032
First paragraph | Full Text | PDF (167K)
See also: News and Views by Kormendy
Onset of antiferromagnetism in heavy-fermion metals p351
A. Schröder, G. Aeppli, R. Coldea, M. Adams, O. Stockert, H.v. Löhneysen, E. Bucher, R. Ramazashvili and P. Coleman
doi:10.1038/35030039
First paragraph | Full Text | PDF (292K)
Detection of geometric phases in superconducting nanocircuits p355
Giuseppe Falci, Rosario Fazio, G. Massimo Palma, Jens Siewert and Vlatko Vedral
doi:10.1038/35030052
First paragraph | Full Text | PDF (228K)
Ordering and self-organization in nanocrystalline silicon p358
G. F. Grom, D. J. Lockwood, J. P. McCaffrey, H. J. Labbé, P. M. Fauchet, B. White, Jr, J. Diener, D. Kovalev, F. Koch and L. Tsybeskov
doi:10.1038/35030062
First paragraph | Full Text | PDF (387K)
Direct electrochemical reduction of titanium dioxide to titanium in molten calcium chloride p361
George Zheng Chen, Derek J. Fray and Tom W. Farthing
doi:10.1038/35030069
First paragraph | Full Text | PDF (250K)
See also: News and Views by Flower
Reduced calcification of marine plankton in response to increased atmospheric CO2 p364
Ulf Riebesell, Ingrid Zondervan, Björn Rost, Philippe D. Tortell, Richard E. Zeebe and François M. M. Morel
doi:10.1038/35030078
First paragraph | Full Text | PDF (226K)
See also: News and Views by Gattuso & Buddemeier
Increased dissolved oxygen in Pacific intermediate waters due to lower rates of carbon oxidation in sediments p367
Lowell D. Stott, William Berelson, Robert Douglas and Donn Gorsline
doi:10.1038/35030084
First paragraph | Full Text | PDF (171K)
Variance in ecological consumer–resource interactions p370
Lisandro Benedetti-Cecchi
doi:10.1038/35030089
First paragraph | Full Text | PDF (177K)
Body image as a visuomotor transformation device revealed in adaptation to reversed vision p374
Kaoru Sekiyama, Satoru Miyauchi, Toshihide Imaruoka, Hiroyuki Egusa and Takara Tashiro
doi:10.1038/35030096
First paragraph | Full Text | PDF (226K) | Supplementary information
IRS-2 pathways integrate female reproduction and energy homeostasis p377
Deborah J. Burks, Jaime Font de Mora, Markus Schubert, Dominic J. Withers, Martin G. Myers, Heather H. Towery, Shari L. Altamuro, Carrie L. Flint and Morris F. White
doi:10.1038/35030105
First paragraph | Full Text | PDF (414K)
Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines p383
Motonari Kondo, David C. Scherer, Toshihiro Miyamoto, Angela G. King, Koichi Akashi, Kazuo Sugamura and Irving L. Weissman
doi:10.1038/35030112
First paragraph | Full Text | PDF (357K) | Supplementary information
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia p386
Todd M. Allen, David H. O'Connor, Peicheng Jing, John L. Dzuris, Bianca R. Mothé, Thorsten U. Vogel, Ed Dunphy, Max E. Liebl, Carol Emerson, Nancy Wilson, Kevin J. Kunstman, Xiaochi Wang, David B. Allison, Austin L. Hughes, Ronald C. Desrosiers, John D. Altman, Steven M. Wolinsky, Alessandro Sette and David I. Watkins
doi:10.1038/35030124
First paragraph | Full Text | PDF (224K) | Supplementary information
See also: News and Views by Walker & Goulder
Superoxide dismutase as a target for the selective killing of cancer cells p390
Peng Huang, Li Feng, Elizabeth A. Oldham, Michael J. Keating and William Plunkett
doi:10.1038/35030140
First paragraph | Full Text | PDF (424K)
See also: News and Views by Cleveland & Kastan
A chemical switch for inhibitor-sensitive alleles of any protein kinase p395
Anthony C. Bishop, Jeffrey A. Ubersax, Dejah T. Petsch, Dina P. Matheos, Nathanael S. Gray, Justin Blethrow, Eiji Shimizu, Joe Z. Tsien, Peter G. Schultz, Mark D. Rose, John L. Wood, David O. Morgan and Kevan M. Shokat
doi:10.1038/35030148
First paragraph | Full Text | PDF (416K) | Supplementary information
The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans p401
Zhaolan Zhou, Ming-juan Luo, Katja Straesser, Jun Katahira, Ed Hurt and Robin Reed
doi:10.1038/35030160
First paragraph | Full Text | PDF (342K) | Supplementary information
Chromodomains are protein–RNA interaction modules p405
Asifa Akhtar, Daniele Zink and Peter B. Becker
doi:10.1038/35030169
First paragraph | Full Text | PDF (372K) | Supplementary information
Image reconstructions of helical assemblies of the HIV-1 CA protein p409
Su Li, Christopher P. Hill, Wesley I. Sundquist and John T. Finch
doi:10.1038/35030177
First paragraph | Full Text | PDF (480K) | Supplementary information
correction: Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells p413
Christian Kurts, Francis R. Carbone, Matthew F. Krummel , Karl M. Koch, Jacques F. A. P. Miller and William R. Heath
doi:10.1038/35030185
erratum: How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis p413
Richard Glynne, Srinivas Akkaraju, James I. Healy, Jane Rayner, Christopher C. Goodnow and David H. Mack
doi:10.1038/35030187
Insight
forewordTaiwan p415
doi:10.1038/35030323
regional insight
Taiwan backs experience in quest for biotech success p417
In under 30 years the tiny island of Taiwan has gone from agricultural backwater to global electronics giant. Now it is turning its attention to biotechnology. But can Taiwan sustain the pace of development?
David Swinbanks and David Cyranoski
doi:10.1038/35030326
Stepping out from the semiconductor shadow p418
David Cyranoski
doi:10.1038/35030333
Building a progressive sci-tech island p419
David Cyranoski
doi:10.1038/35030337
A science giant rises out of the rice fields p420
David Cyranoski
doi:10.1038/35030340
Nicky Lu — entrepreneur p421
David Cyranoski
doi:10.1038/35030343
Beating the odds p422
David Cyranoski
doi:10.1038/35030347
Homeless, but heading for success p424
David Swinbanks
doi:10.1038/35030350
The rodent route to celebrity p425
David Cyranoski
doi:10.1038/35030353
Bridging the gap p426
David Swinbanks
doi:10.1038/35030357
Careers and Recruitment
Unfavourable economics put postdocs across Europe under strain p427
Travel may broaden the mind, but for many postdocs taking fellowships in the European Union, it is causing financial hardship, says Natasha Loder.
Natasha Loder
doi:10.1038/35030308
Finding a focus for European postdocs p427
Natasha Loder
doi:10.1038/35030311
Trouble at home p428
Xavier Bosch
doi:10.1038/35030313
Postdocs reject academic research p429
With full-time positions in universities at a premium, postdocs are looking to government labs and industry for jobs, says Potter Wickware.
Potter Wickware
doi:10.1038/35030316
Organization pays p430
Potter Wickware
doi:10.1038/35030320
