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Insight
Nature 407, 249-257 (14 September 2000) | doi:10.1038/35025220
Open Innovation Challenges
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Fast Growth of Transformed Soybean Shoots
A method for accelerating growth of soybean shoots is desired.
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Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
- More Challenges
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Professorship in Agricultural Engineering
- University of Natural Resources and Applied Life Sciences Vienna
- Vienna, Austria
Principal Investigators
- CeMM, The Research Center for Molecular Medicine
- Vienna, Austria
review article Angiogenesis in cancer and other diseases
Peter Carmeliet1 & Rakesh K. Jain2
Abstract
Pathological angiogenesis is a hallmark of cancer and various ischaemic and inflammatory diseases. Concentrated efforts in this area of research are leading to the discovery of a growing number of pro- and anti-angiogenic molecules, some of which are already in clinical trials. The complex interactions among these molecules and how they affect vascular structure and function in different environments are now beginning to be elucidated. This integrated understanding is leading to the development of a number of exciting and bold approaches to treat cancer and other diseases. But owing to several unanswered questions, caution is needed.
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