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Nature 406, 354-356 (27 July 2000) | doi:10.1038/35019227

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Cell cycle: Conducting the mitotic symphony

David Cortez1 & Stephen J. Elledge1

The process by which chromosomes condense and segregate during mitosis (nuclear division) can be likened to a symphony in which many instruments, working individually, are coordinated to produce a collective piece of elegance and beauty. The conductor, with a wave of the baton, ensures that each musical instrument enters the symphony at the proper time.

  1. David Cortez and Stephen J. Elledge are in the Verna and Marrs McLean Department of Biochemistry and Molecular Biology, and the Howard Hughes Medical Institute, One Baylor Plaza, Baylor College of Medicine, Houston, Texas 77030, USA.

Correspondence to: Stephen J. Elledge1 e-mail: Email: selledge@bcm.tmc.edu