Despite the pervasive tension between AIDS researchers and the South African government, last week's international AIDS conference in Durban was successful on several fronts.
doi:10.1038/35018685
Table of contents
Volume 406 Number 6793 pp219-330
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Opinion
Grounds for hope on AIDS in Africa p219
SOS (again) at the Department of Energy p219
Congress should provide adequate support for facilities operated on behalf of all US scientists.
doi:10.1038/35018687
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News
Large research facilities to lose out in science spending spree? p221
Jordan chosen to open SESAME p221
UK space strategy slammed as lacking funds and vision p222
Cluster leaves the ground — at last p222
Diplomatic Mandela calls for action on HIV... p223
...as South Africa considers its options after free drugs offer p223
Diabetes therapy boosts stem-cell campaign p224
Industry considers carbon catching p224
Enhanced advisory role urged for former EU nuclear labs p225
Brown boosts British science base p225
Recriminations and confusion over 'fake' coelacanth photo p225
Anti-smoking critic wins campaigning right p226
German librarians cautious of brave new digital world p227
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News Feature
Bones, molecules...or both? p230
Evolutionary trees constructed by studying biological molecules often don't resemble those drawn up from morphology. Can the two ever be reconciled, asks Trisha Gura
Trisha Gura
doi:10.1038/35018729
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Correspondence
Caution is sensible, but give biotech a chance to show the good it can do p234
A fault in the 'weak San Andreas' theory p234
That famous double helix takes a sinister turn p234
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Book Reviews
The biotechnologist's jungle book p235
doi:10.1038/35018619
Healing hues p235
doi:10.1038/35018621
A function for dysfunction p236
doi:10.1038/35018624
Channelling other energies p236
doi:10.1038/35018626
Conservation gets heavy p237
doi:10.1038/35018629
Chemistry's Canterbury Tales p238
New in paperback p238
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Millennium Essay
Jumbo p239
The revolutionary machine that shrank the world.
Vaclav Smil
doi:10.1038/35018651
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Futures
All is not lost p241
By resurrecting extinct infodiversity, we may save our own culture.
Scott Westerfeld
doi:10.1038/35018654
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News and Views
光学：光の速さを超える光？
Faster than a speeding photon p243
The textbooks say nothing can travel faster than light, not even light itself. New experiments show that this is no longer true, raising questions about the maximum speed at which we can send information.
Jon Marangos
doi:10.1038/35018657
生物物理学：動き始めた科学
Biophysics: Science in motion p244
神経生物学：平行した感覚
Neurobiology: Parallel sensing p245
大気物理学：水蒸気に光を当てる
Atmospheric physics: Enlightening water vapour p247
人間行動：フェアな試合
Human behaviour: Fair game p248
構造生物学：凍結防止の新メンバー
Structural biology: Adding to the antifreeze agenda p249
数学：タンパク質とDNAの上手な詰め方
Mathematics: Best packing in proteins and DNA p251
100 and 50 years ago p252
細胞生物学：タンパク質の蓄積
Cell biology: A protein accumulator p253
Daedalus: Pulses of the mind p254
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Brief Communications
Spider manipulation by a wasp larva p255
A parasitic wasp forces its host to weave a special web for its own ends.
William G. Eberhard
doi:10.1038/35018636
Phytochemistry: Heat-stable antifreeze protein from grass p256
Chris Sidebottom, Sarah Buckley, Paul Pudney, Sarah Twigg, Carl Jarman, Chris Holt, Julia Telford, Andrew McArthur, Dawn Worrall, Rod Hubbard and Peter Lillford
doi:10.1038/35018639
Cell differentiation: Hepatocytes from non-hepatic adult stem cells p257
Malcolm R. Alison, Richard Poulsom, Rosemary Jeffery, Amar P. Dhillon, Alberto Quaglia, Joe Jacob, Marco Novelli, Grant Prentice, Jill Williamson and Nicholas A. Wright
doi:10.1038/35018642
Top of pageStructure of the Fc fragment of human IgE bound to its high-affinity
receptor Fc
The 3.2-Å crystal structure of the human IgG1 Fc fragment–Fc
Articles
生化学：高親和性受容体FcεRIαと結合したヒトIgEのFc断片の構造
Structure of the Fc fragment of human IgE bound to its high-affinity
receptor Fc
RI
p259
Scott C. Garman, Beth A. Wurzburg, Svetlana S. Tarchevskaya, Jean-Pierre Kinet and Theodore S. Jardetzky
doi:10.1038/35018500
日本語要約 | Full Text | PDF (431K)
生化学：ヒトIgG1 Fc断片‐FcγRIII複合体の3.2Å結晶構造
The 3.2-Å crystal structure of the human IgG1 Fc fragment–Fc
RIII
complex p267
Peter Sondermann, Robert Huber, Vaughan Oosthuizen and Uwe Jacob
doi:10.1038/35018508
日本語要約 | Full Text | PDF (662K)
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Mimicry of ice structure by surface hydroxyls and water of a
Letters to Nature
宇宙：結晶性の塵の断片から彗星の年齢を決める
Determining the ages of comets from the fraction of crystalline dust p275
Joseph A. Nuth, III, Hugh G. M. Hill and Gunther Kletetschka
doi:10.1038/35018516
日本語要約 | Full Text | PDF (211K)
物理：利得補助による超高速の光の伝搬
Gain-assisted superluminal light propagation p277
物性：磁気センサーにおける非同一直線状態
Non-collinear states in magnetic sensors p280
Adrian Taga, Lars Nordström, Peter James, Börje Johansson and Olle Eriksson
doi:10.1038/35018528
日本語要約 | Full Text | PDF (344K)
物性：乱れが存在する際の渦糸格子融解過程の画像化
Imaging the vortex-lattice melting process in the presence of disorder p282
Alex Soibel, Eli Zeldov, Michael Rappaport, Yuri Myasoedov, Tsuyoshi Tamegai, Shuuichi Ooi, Marcin Konczykowski and Vadim B. Geshkenbein
doi:10.1038/35018532
日本語要約 | Full Text | PDF (927K)
数学：密集したひもの最適形状
Optimal shapes of compact strings p287
Amos Maritan, Cristian Micheletti, Antonio Trovato and Jayanth R. Banavar
doi:10.1038/35018538
日本語要約 | Full Text | PDF (161K)
地球：全地球的な雷光活動と対流圏上部水蒸気に関連がある証拠
Evidence for a link between global lightning activity and upper tropospheric water vapour p290
地球：Pa-Th-U同位体データから推定された地球マントルのリソスフェア内の溶融
Melting of the Earth's lithospheric mantle inferred from protactinium– thorium–uranium isotopic data p293
Yemane Asmerom, Hai Cheng, Rebecca Thomas, Marc Hirschmann and R. Lawrence Edwards
doi:10.1038/35018550
日本語要約 | Full Text | PDF (263K)
生態：オガワコマドリの雌は婚外交尾で子の免疫応答能を高める
Female bluethroats enhance offspring immunocompetence through extra-pair copulations p296
Arild Johnsen, Vegard Andersen, Christine Sunding and Jan T. Lifjeld
doi:10.1038/35018556
日本語要約 | Full Text | PDF (181K)
生理：磁鉄鉱は脊椎動物磁気受容器の特徴である
Magnetite defines a vertebrate magnetoreceptor p299
Carol E. Diebel, Roger Proksch, Colin R. Green, Peter Neilson and Michael M. Walker
doi:10.1038/35018561
日本語要約 | Full Text | PDF (288K)
神経：体性感覚の視床皮質路での時系列的符号から発火頻度符号への変換
Transformation from temporal to rate coding in a somatosensory thalamocortical pathway p302
Ehud Ahissar, Ronen Sosnik and Sebastian Haidarliu
doi:10.1038/35018568
発生：線虫のニューロンで正常な形態と機能の発現に必要なプレセニリン
Presenilin is required for proper morphology and function of neurons in C. elegans p306
Nicole Wittenburg, Stefan Eimer, Bernard Lakowski, Sascha Röhrig, Claudia Rudolph and Ralf Baumeister
doi:10.1038/35018575
日本語要約 | Full Text | PDF (215K)
免疫：ケモカインの働きによる正のフィードバック・ループがリンパ濾胞を構築する
A chemokine-driven positive feedback loop organizes lymphoid follicles p309
K. Mark Ansel, Vu N. Ngo, Paul L. Hyman, Sanjiv A. Luther, Reinhold Förster, Jonathon D. Sedgwick, Jeffrey L. Browning, Martin Lipp and Jason G. Cyster
doi:10.1038/35018581
日本語要約 | Full Text | PDF (611K)
細胞：活性部位ドメインをグループIIイントロンの5′スプライス部位に結びつけるRNAの三次構造
A tertiary interaction that links active-site domains to the 5' splice site of a group II intron p315
Marc Boudvillain, Alexandre de Lencastre and Anna Marie Pyle
doi:10.1038/35018589
細胞：ペプチド合成の転位の際に起こる、リボソームのつめ車状サブユニット再編成
A ratchet-like inter-subunit reorganization of the ribosome during translocation p318
Joachim Frank and Rajendra Kumar Agrawal
doi:10.1038/35018597
生化学：表面ヒドロキシル基とβヘリックス凍結防止タンパク質の水による、氷型構造の模倣
Mimicry of ice structure by surface hydroxyls and water of a 
-helix
antifreeze protein p322
Yih-Cherng Liou, Ante Tocilj, Peter L. Davies and Zongchao Jia
doi:10.1038/35018604
日本語要約 | Full Text | PDF (242K)
生化学：昆虫の高活性凍結防止タンパク質のβヘリックス構造と氷型結合特性
-Helix structure and ice-binding properties of a hyperactive antifreeze
protein from an insect p325
Steffen P. Graether, Michael J. Kuiper, Stéphane M. Gagné, Virginia K. Walker, Zongchao Jia, Brian D. Sykes and Peter L. Davies
doi:10.1038/35018610
日本語要約 | Full Text | PDF (348K)
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New on the Market
Counting on proteomics p329
Download a trial of image analysis software, and seek those proteins.
doi:10.1038/35018645
