Figures and Tables

From the following article:

A chemokine-driven positive feedback loop organizes lymphoid follicles

K. Mark Ansel, Vu N. Ngo, Paul L. Hyman, Sanjiv A. Luther, Reinhold Förster, Jonathon D. Sedgwick, Jeffrey L. Browning, Martin Lipp and Jason G. Cyster

Nature 406, 309-314(20 July 2000)

doi:10.1038/35018581

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Figure 1

BLC genomic locus and lack of BLC mRNA and protein in BLC-/- mice.

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Figure 2

Absence of primary follicles and FDCs in BLC-/- mice, and defective homing of CXCR5-/- B cells to lymph node follicles.

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Figure 3

Membrane LTalpha1beta2 expression on B cells in peripheral lymphoid tissues and dependence on BLC.

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Figure 4

BLC induces LTalpha1beta2 upregulation on B cells in vitro.

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Figure 5

Misplaced FDC-containing germinal centres in BLC-/- mice and BLC-independent expression of LTalpha1beta2 on germinal centre B cells.

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Table 1

Defective lymph node and Peyer's patch development in BLC and CXCR5-deficient mice

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