Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 406, 135-136 (13 July 2000) | doi:10.1038/35018190
Apoptosis: The little devil of death
Vincenzo De Laurenzi1 & Gerry Melino1
Top of page
Abstract
There are 'roadblocks' at several points in the signalling pathways that control programmed cell death. When the cell needs to die, these roadblocks must be removed, and a vertebrate protein that removes one such block has now been identified.
Cell suicide is an essential, everyday event in developing and adult multicellular organisms. Indeed, alterations in the ratio of proliferating to dying cells result in several diseases, including cancer and autoimmunity.
To read this story in full you will need to login or make a payment (see right).