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TY  - GEN
AU  - Weatherall, D. J.
AU  - Clegg, J. B.
TI  - The Thalassemia
Syndromes
PY  - 1981///
ER  -

TY  - GEN
AU  - Nathan, D. G.
AU  - 
Oski, F. A.
TI  - Hematology of Infancy and Childhood

PY  - 1998///
ER  -

TY  - JOUR
AU  - Sadelain, M.
TI  - 
Genetic treatment of the haemoglobinopathies: recombinations and new combinations.

JA  - Br. J. Haematol.
PY  - 1997///
VL  - 98
SP  - 247
EP  - 
253
M3  - 10.1046/j.1365-2141.1997.2313048.x
N1  - 10.1046/j.1365-2141.1997.2313048.x
UR  - http://dx.doi.org/10.1046/j.1365-2141.1997.2313048.x
ER  -

TY  - JOUR
AU  - Boulad, F.
TI  - Bone marrow transplantation for homozygous beta-thalassemia.

JA  - Ann. N. Y. Acad. Sci.
PY  - 1998///
VL  - 850
SP  - 498
EP  - 
502
ER  -

TY  - JOUR
AU  - Rivella, S.
AU  - 
Sadelain, M.
TI  - Genetic treatment of severe hemoglobinopathies:
the combat against transgene variegation and transgene silencing.
JA  - 
Semin. Hematol.
PY  - 1998///
VL  - 35
SP  - 112
EP  - 125
ER  -

TY  - JOUR
AU  - Tuan, D.
AU  - 
Solomon, W.
AU  - Li, Q.
AU  - London, I. M.
TI  - The [ldquo]beta-like-globin[rdquo]
gene domain in human erythroid cells.
JA  - Proc. Natl Acad. Sci. USA

PY  - 1985///
VL  - 82
SP  - 6384
EP  - 6388
ER  -

TY  - JOUR
AU  - Forrester, W. C.
AU  - 
Takegawa, S.
AU  - Papayannopoulou, 
T.
AU  - Stamatoyannopoulos, G.
AU  - Groudine, M.
TI  - Evidence for
a locus activation region: the formation of developmentally stable hypersensitive
sites in globin-expressing hybrids.
JA  - Nucleic Acids Res.
PY  - 1987///
VL  - 
15
SP  - 10159
EP  - 10177
ER  -

TY  - JOUR
AU  - Grosveld, F.
AU  - 
van Assendelft, G. B.
AU  - Greaves, 
D. R.
AU  - Kollias, G.
TI  - 
Position-independent, high-level expression of the human beta-globin gene
in transgenic mice.
JA  - Cell
PY  - 1987///
VL  - 51
SP  - 975
EP  - 
985
M3  - 10.1016/0092-8674(87)90584-8
N1  - 10.1016/0092-8674(87)90584-8
UR  - http://dx.doi.org/10.1016/0092-8674(87)90584-8
ER  -

TY  - JOUR
AU  - Sadelain, M.
AU  - 
Wang, C. H.
AU  - Antoniou, M.

AU  - Grosveld, F.
AU  - 
Mulligan, R. C.
TI  - Generation of a high-titer retroviral
vector capable of expressing high levels of the human beta-globin gene.
JA  - 
Proc. Natl Acad. Sci. USA
PY  - 1995///
VL  - 92
SP  - 6728
EP  - 
6732
ER  -

TY  - JOUR
AU  - Leboulch, P.
TI  - Mutagenesis of retroviral vectors transducing human beta-globin
gene and beta-globin locus control region derivatives results in stable transmission
of an active transcriptional structure.
JA  - EMBO J.
PY  - 1994///
VL  - 13
SP  - 
3065
EP  - 3076
ER  -

TY  - JOUR
AU  - Raftopoulos, H.
AU  - 
Ward, M.
AU  - Leboulch, P.
AU  - Bank, A.
TI  - Long-term transfer
and expression of the human beta-globin gene in a mouse transplant model.

JA  - Blood
PY  - 1997///
VL  - 90
SP  - 3414
EP  - 3422
ER  -

TY  - JOUR
AU  - Grosveld, F.
TI  - The dynamics of globin gene expression and gene therapy vectors.

JA  - Semin. Hematol.
PY  - 1998///
VL  - 35
SP  - 105
EP  - 
111
ER  -

TY  - JOUR
AU  - Bulger, M.
AU  - 
Groudine, M.
TI  - Looping versus linking: toward
a model for long-distance gene activation.
JA  - Genes Dev.
PY  - 1999///
VL  - 
13
SP  - 2465
EP  - 2477
M3  - 10.1101/gad.13.19.2465
N1  - 10.1101/gad.13.19.2465
UR  - http://dx.doi.org/10.1101/gad.13.19.2465
ER  -

TY  - JOUR
AU  - Higgs, D. R.
TI  - 
Do LCRs open chromatin domains?
JA  - Cell
PY  - 1998///
VL  - 95
SP  - 
299
EP  - 302
M3  - 10.1016/S0092-8674(00)81761-4
N1  - 10.1016/S0092-8674(00)81761-4
UR  - http://dx.doi.org/10.1016/S0092-8674(00)81761-4
ER  -

TY  - JOUR
AU  - Engel, J. D.
AU  - 
Tanimoto, K.
TI  - Looping, linking, and chromatin
activity: new insights into beta-globin locus regulation.
JA  - Cell

PY  - 2000///
VL  - 100
SP  - 499
EP  - 502
M3  - 10.1016/S0092-8674(00)80686-8
N1  - 10.1016/S0092-8674(00)80686-8
UR  - http://dx.doi.org/10.1016/S0092-8674(00)80686-8
ER  -

TY  - JOUR
AU  - Novak, U.
AU  - 
Harris, E. A.
AU  - Forrester, 
W.
AU  - Groudine, M.
AU  - 
Gelinas, R.
TI  - High-level beta-globin expression
after retroviral transfer of locus activation region-containing human beta-globin
gene derivatives into murine erythroleukemia cells.
JA  - Proc. Natl
Acad. Sci. USA
PY  - 1990///
VL  - 87
SP  - 3386-3390
ER  -

TY  - JOUR
AU  - Talbot, D.
TI  - A dominant control region from the human beta-globin locus
conferring integration site-independent gene expression.
JA  - Nature

PY  - 1989///
VL  - 338
SP  - 352[mdash]355
ER  -

TY  - JOUR
AU  - Bungert, J.
TI  - Synergistic regulation of human beta-globin gene switching
by locus control region elements HS3 and HS4.
JA  - Genes Dev.
PY  - 1995///
VL  - 
9
SP  - 3083
EP  - 3096
ER  -

TY  - JOUR
AU  - Malim, M. H.
AU  - 
Hauber, J.
AU  - Le, S. Y.
AU  - 
Maizel, J. V.
AU  - Cullen, 
B. R.
TI  - The HIV-1 rev trans-activator acts through a structured
target sequence to activate nuclear export of unspliced viral mRNA.
JA  - 
Nature
PY  - 1989///
VL  - 338
SP  - 254
EP  - 257
M3  - 10.1038/338254a0
N1  - 10.1038/338254a0
UR  - http://dx.doi.org/10.1038/338254a0
ER  -

TY  - JOUR
AU  - Porcu, S.
TI  - The human beta globin locus introduced by YAC transfer exhibits
a specific and reproducible pattern of developmental regulation in transgenic
mice.
JA  - Blood
PY  - 1997///
VL  - 90
SP  - 4602
EP  - 4609

ER  -

TY  - JOUR
AU  - Yang, B.
TI  - A mouse model for beta 0-thalassemia.
JA  - Proc. Natl Acad.
Sci. USA
PY  - 1995///
VL  - 92
SP  - 11608
EP  - 11612
ER  -

TY  - JOUR
AU  - Fabry, M. E.
TI  - A second generation transgenic mouse model expressing both
hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity.

JA  - Blood
PY  - 1995///
VL  - 86
SP  - 2419
EP  - 2428
ER  -

TY  - JOUR
AU  - Esan, G. J.
AU  - 
Adesina, T. A.
AU  - Luzzatto, 
L.
TI  - Synthesis of haemoglobins specified by allelic genes
in human heterozygotes.
JA  - Nature
PY  - 1971///
VL  - 229
SP  - 143
EP  - 
145
ER  -

TY  - GEN
AU  - Stamatoyannopoulos, G.
AU  - 
Nienhuis, A. W.
AU  - Majerus, 
P.
AU  - Varmus, H.
TI  - 
The Molecular Basis Of Blood Diseases
PY  - 1994///
ER  -

TY  - JOUR
AU  - Miyoshi, H.
AU  - 
Smith, K. A.
AU  - Mosier, D. E.

AU  - Verma, I. M.
AU  - 
Torbett, B. E.
TI  - Transduction of human CD34+ cells
that mediate long-term engraftment of NOD/SCID mice by HIV vectors.
JA  - 
Science
PY  - 1999///
VL  - 283
SP  - 682
EP  - 686
M3  - 10.1126/science.283.5402.682
N1  - 10.1126/science.283.5402.682
UR  - http://dx.doi.org/10.1126/science.283.5402.682
ER  -

TY  - JOUR
AU  - Amado, R. G.
AU  - 
Chen, I. S.
TI  - Lentiviral vectors[mdash]the promise
of gene therapy within reach?
JA  - Science
PY  - 1999///
VL  - 285
SP  - 
674
EP  - 676
M3  - 10.1126/science.285.5428.674
N1  - 10.1126/science.285.5428.674
UR  - http://dx.doi.org/10.1126/science.285.5428.674
ER  -

TY  - JOUR
AU  - Zufferey, R.
AU  - 
Nagy, D.
AU  - Mandel, R. J.
AU  - 
Naldini, L.
AU  - Trono, 
D.
TI  - Multiply attenuated lentiviral vector achieves efficient
gene delivery in vivo.
JA  - Nature Biotechnol.
PY  - 1997///
VL  - 15
SP  - 
871
EP  - 875
M3  - 10.1038/nbt0997-871
N1  - 10.1038/nbt0997-871
UR  - http://dx.doi.org/10.1038/nbt0997-871
ER  -

TY  - JOUR
AU  - Dull, T.
TI  - A third-generation lentivirus vector with a conditional packaging
system.
JA  - J. Virol.
PY  - 1998///
VL  - 72
SP  - 8463
EP  - 
8471
ER  -

TY  - JOUR
AU  - Gallardo, H. F.
AU  - 
Tan, C.
AU  - Ory, D.
AU  - Sadelain, M.
TI  - Recombinant retroviruses
pseudotyped with the vesicular stomatitis virus G glycoprotein mediate both
stable gene transfer and pseudotransduction in human peripheral blood lymphocytes.

JA  - Blood
PY  - 1997///
VL  - 90
SP  - 952
EP  - 957
ER  -

TY  - JOUR
AU  - Rivella, S.
AU  - 
Callegari, J. A.
AU  - May, C
AU  - 
Tan, C.
AU  - Sadelain, M.

TI  - The cHS4 insulator increases the probability of retroviral
expression at random chromosomal integration sites.
JA  - J. Virol.
PY  - 2000///
VL  - 
74
SP  - 4679
EP  - 4687
M3  - 10.1128/JVI.74.10.4679-4687.2000
N1  - 10.1128/JVI.74.10.4679-4687.2000
UR  - http://dx.doi.org/10.1128/JVI.74.10.4679-4687.2000
ER  -
