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Nature 405, 892-895 (22 June 2000) | doi:10.1038/35016175

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Neurobiology: Self-repair in the brain

Anders Björklund1 & Olle Lindvall1

In tissues that can repair themselves, such as skin and liver, dead cells can be replaced either by the proliferation of nearby cells or by the activation of resident stem cells — undifferentiated cells with the potential to generate many different cell types. The brain apparently lacks this regenerative capacity, making it particularly vulnerable to injury or disease.

  1. Anders Björklund and Olle Lindvall are at the Wallenberg Neuroscience Center, Lund University, Sölvegatan 17, S-223 62 Lund, Sweden.
    E-mails: Email:  anders.bjorklund@mphy.lu.se and Email: olle.lindvall@neurol.lu.se