Opinion

Debates over credit for the annotation of genomes p719

Researchers who devote themselves to sequencing genomes often lack the time to interpret their results. Others don't. The tensions that can result reflect the need for a rethink of sequencers' priorities or a change in approach to collaboration.

doi:10.1038/35015742

Full Text | PDF (58K)

News

Relations thaw between genome rivals as finish line draws near p721

Paul Smaglik

doi:10.1038/35015744

Full Text | PDF (120K)

China warned of AIDS 'disaster' p721

doi:10.1038/35015747

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Canada unifies medical research community p722

David Spurgeon

doi:10.1038/35015749

Full Text | PDF (77K)

Miniature antennas will eavesdrop on the Universe p722

Steve Nadis

doi:10.1038/35015752

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European centres rebuffed in infrastructure funding bid p723

Quirin Schiermeier

doi:10.1038/35015755

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Spanish postgrads push for better employment rights p723

Xavier Bosch

doi:10.1038/35015758

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NIH panel may increase gene-trial scrutiny... p724

Paul Smaglik

doi:10.1038/35015760

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...as Europe's 'excessive secrecy' is deplored p724

Declan Butler

doi:10.1038/35015763

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UK researchers call for limits on animal experiment 'red tape' p725

Natasha Loder

doi:10.1038/35015765

Full Text | PDF (217K)

US climate report underlines local impacts of warming p725

Paul Smaglik

doi:10.1038/35015767

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Los Alamos 'loses' key weapons data p725

Rex Dalton

doi:10.1038/35015770

Full Text | PDF (217K)

News in brief p726

doi:10.1038/35015772

Full Text | PDF (71K)

News Feature

One for all — and all for one p728

Hubert Markl, president of Germany's Max Planck Society, wants to make the organization work as a coherent whole. As the society prepared for its annual meeting in Munich, he explained his vision to Alison Abbott.

Alison Abbott

doi:10.1038/35015775

Full Text | PDF (129K)

Nanotech thinks big p730

The science of the incredibly small is shedding its sci-fi image. An anticipated influx of US government funds is nurturing a new wave of interdisciplinary nanoscale research, says Colin Macilwain.

Colin Macilwain

doi:10.1038/35015778

Full Text | PDF (346K)

Correspondence

'Underachieving' centre has not only struck gold but made good use of it p733

Helmut Blöcker

doi:10.1038/35015785

Full Text | PDF (55K)

Jumping the gun on mouse gene expression p733

Magdalena Zernicka-Goetz

doi:10.1038/35015787

Full Text | PDF (55K)

Setbacks don't dampen the energy of US physics p733

Andrew M. Sessler

doi:10.1038/35015789

Full Text | PDF (55K)

How the GM industry writes its own rules p733

Philip L. Bereano

doi:10.1038/35015791

Full Text | PDF (55K)

W. D. Hamilton memorial p733

Richard Dawkins

doi:10.1038/35015793

Full Text | PDF (55K)

Book Reviews

When Galileo turned to verse p735

The English translation of an obscure, 400-year-old Italian curiosity.

Dava Sobel reviews Against the Donning of the Gown: Contro Il Portar La Toga by Galileo Galilei and Giovanni F. Bignami

doi:10.1038/35015617

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Aping human societies p735

Adrienne Zihlman reviews Hierarchy in the Forest: The Evolution of Egalitarian Behavior by Christopher Boehm

doi:10.1038/35015620

Full Text | PDF (263K)

A helping hand on elementary matters p736

P. W. Anderson reviews Lucifer's Legacy: The Meaning of Asymmetry by Frank Close

doi:10.1038/35015623

Full Text | PDF (252K)

A double-take on nature's helix p737

doi:10.1038/35015625

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Portrait of an élite world p737

John Gascoigne reviews Cavendish: The Experimental Life by Christa Jungnickel and Russell McCormmach

doi:10.1038/35015628

Full Text | PDF (162K)

New in paperback p738

doi:10.1038/35015631

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Millennium Essay

An unholy alliance p739

The Nazis showed that 'politically responsible' science risks losing its soul.

Ute Deichmann

doi:10.1038/35015633

Full Text | PDF (140K)

Futures

Another green world p741

There's more to industrial waste than chimneys and slag heaps.

Henry Wessells

doi:10.1038/35015636

Full Text | PDF (123K)

News and Views

Oceanography: Moon, tides and climate p743

The view that much of the energy of ocean tides is dissipated in deep water, rather than in shallow coastal seas, now finds observational support. Curiously, the results bear upon our understanding of climate change.

Carl Wunsch

doi:10.1038/35015639

Full Text | PDF (182K)

Demography: Greater lifetime expectations p744

Shiro Horiuchi

doi:10.1038/35015642

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Fluid dynamics: Smart polymer solutions p745

Jacob Klein

doi:10.1038/35015645

Full Text | PDF (319K)

Neurobiology: Nervous engineering p747

Melitta Schachner

doi:10.1038/35015648

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Mathematics: Curves and numbers p748

Ivar Ekeland

doi:10.1038/35015651

Full Text | PDF (137K)

Cell biology: GTPase traffic control p749

Channing J. Der and William E. Balch

doi:10.1038/35015654

Full Text | PDF (269K)

100 and 50 years ago p749

doi:10.1038/35015657

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Genetics: Fungal get-together p751

Nicholas P. Money

doi:10.1038/35015659

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Daedalus: Eye contact p752

David Jones

doi:10.1038/35015662

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erratum: Electrons in the looking glass p752

doi:10.1038/35015664

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erratum: Three's a crowd p752

doi:10.1038/35015666

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Brief Communications

Survival of the Irish elk into the Holocene p753

Giant deer on the Isle of Man around 9,000 years ago may have been the last of the line.

Silvia Gonzalez, Andrew C. Kitchener and Adrian M. Lister

doi:10.1038/35015668

First paragraph | Full Text | PDF (143K)

Cell signalling: Control of free calcium in plant cell nuclei p754

Nicolas Pauly, Marc R. Knight, Patrice Thuleau, Arnold H. van der Luit, Marc Moreau, Anthony J. Trewavas, Raoul Ranjeva and Christian Mazars

doi:10.1038/35015671

First paragraph | Full Text | PDF (126K)

Cell biology: Risky immortalization by telomerase p755

Jing Wang, Gregory J. Hannon and David H. Beach

doi:10.1038/35015674

First paragraph | Full Text | PDF (154K)

Insect perception: Do cockroaches 'know' about fluid dynamics? p756

D. Rinberg and H. Davidowitz

doi:10.1038/35015677

First paragraph | Full Text | PDF (125K)

erratum: Focusing hard X-rays with old LPs p756

doi:10.1038/35015680

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Article

The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling p757

Michael Oelgeschläger, Juan Larraín, Douglas Geissert and Eddy M. De Robertis

doi:10.1038/35015500

Abstract | Full Text | PDF (462K)

Letters to Nature

Kondo effect in an integer-spin quantum dot p764

S. Sasaki, S. De Franceschi, J. M. Elzerman, W. G. van der Wiel, M. Eto, S. Tarucha and L. P. Kouwenhoven

doi:10.1038/35015509

First paragraph | Full Text | PDF (400K)

Direct observation of the alignment of ferromagnetic spins by antiferromagnetic spins p767

F. Nolting, A. Scholl, J. Stöhr, J. W. Seo, J. Fompeyrine, H. Siegwart, J.-P. Locquet, S. Anders, J. Lüning, E. E. Fullerton, M. F. Toney, M. R. Scheinfein and H. A. Padmore

doi:10.1038/35015515

First paragraph | Full Text | PDF (202K)

Reversible electromechanical characteristics of carbon nanotubes under local-probe manipulation p769

Thomas W. Tombler, Chongwu Zhou, Leo Alexseyev, Jing Kong, Hongjie Dai, Lei Liu, C. S. Jayanthi, Meijie Tang and Shi-Yu Wu

doi:10.1038/35015519

First paragraph | Full Text | PDF (249K)

Controlling droplet deposition with polymer additives p772

Vance Bergeron, Daniel Bonn, Jean Yves Martin and Louis Vovelle

doi:10.1038/35015525

First paragraph | Full Text | PDF (269K)

See also: News and Views by Klein

Significant dissipation of tidal energy in the deep ocean inferred from satellite altimeter data p775

G. D. Egbert and R. D. Ray

doi:10.1038/35015531

First paragraph | Full Text | PDF (254K)

See also: News and Views by Wunsch

A larger pool of ozone-forming carbon compounds in urban atmospheres p778

Alastair C. Lewis, Nicola Carslaw, Philip J. Marriott, Russel M. Kinghorn, Paul Morrison, Andrew L. Lee, Keith D. Bartle and Michael J. Pilling

doi:10.1038/35015540

First paragraph | Full Text | PDF (206K)

Re–Os isotopic evidence for a lower crustal origin of massif-type anorthosites p781

Henrik Schiellerup, David D. Lambert, Tore Prestvik, Brian Robins, Jannene S. McBride and Rune B. Larsen

doi:10.1038/35015546

First paragraph | Full Text | PDF (140K) | Supplementary information

Unrelated helpers in a social insect p784

David C. Queller, Francesca Zacchi, Rita Cervo, Stefano Turillazzi, Michael T. Henshaw, Lorenzo A. Santorelli and Joan E. Strassmann

doi:10.1038/35015552

First paragraph | Full Text | PDF (149K)

Female feral fowl eject sperm of subdominant males p787

T. Pizzari and T. R. Birkhead

doi:10.1038/35015558

First paragraph | Full Text | PDF (120K)

A universal pattern of mortality decline in the G7 countries p789

Shripad Tuljapurkar, Nan Li and Carl Boe

doi:10.1038/35015561

First paragraph | Full Text | PDF (207K)

See also: News and Views by Horiuchi

Ultrasensitive pheromone detection by mammalian vomeronasal neurons p792

Trese Leinders-Zufall, Andrew P. Lane, Adam C. Puche, Weidong Ma, Milos V. Novotny, Michael T. Shipley and Frank Zufall

doi:10.1038/35015572

First paragraph | Full Text | PDF (395K)

Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia p797

N. M. Page, R. J. Woods, S. M. Gardiner, K. Lomthaisong, R. T. Gladwell, D. J. Butlin, I. T. Manyonda and P. J. Lowry

doi:10.1038/35015579

First paragraph | Full Text | PDF (258K) | Supplementary information

The -subunit of the coatomer complex binds Cdc42 to mediate transformation p800

Wen Jin Wu, Jon W. Erickson, Rui Lin and Richard A. Cerione

doi:10.1038/35015585

First paragraph | Full Text | PDF (277K)

See also: News and Views by Der & Balch

Two-headed binding of a processive myosin to F-actin p804

Matthew L. Walker, Stan A. Burgess, James R. Sellers, Fei Wang, John A. Hammer, III, John Trinick and Peter J. Knight

doi:10.1038/35015592

First paragraph | Full Text | PDF (340K)

The lyase activity of the DNA repair protein -polymerase protects from DNA-damage-induced cytotoxicity p807

Robert W. Sobol, Rajendra Prasad, Andrea Evenski, Audrey Baker, Xiao-Ping Yang, Julie K. Horton and Samuel H. Wilson

doi:10.1038/35015598

First paragraph | Full Text | PDF (162K)

Observations of light-induced structural changes of retinal within rhodopsin p810

Gerhard Gröbner, Ian J. Burnett, Clemens Glaubitz, Gregory Choi, A. James Mason and Anthony Watts

doi:10.1038/35015604

First paragraph | Full Text | PDF (267K)

Atomically defined mechanism for proton transfer to a buried redox centre in a protein p814

Kaisheng Chen, Judy Hirst, Raul Camba, Christopher A. Bonagura, C. David Stout, Barbara. K. Burgess and Fraser A. Armstrong

doi:10.1038/35015610

First paragraph | Full Text | PDF (290K) | Supplementary information

Insight

Functional genomics p819

doi:10.1038/35015738

Full Text | PDF (205K)

Exploring genome space p820

The completion of entire genome sequences of many experimental organisms, and the promise that the human genome will be completed in the next year, find biology suddenly awash in genome-based data. Scientists are scrambling to develop new technologies that exploit genome data to ask entirely new kinds of questions about the complex nature of living cells.

Ognjenka Goga Vukmirovic and Shirley M. Tilghman

doi:10.1038/35015690

First paragraph | Full Text | PDF (212K)

Protein function in the post-genomic era p823

David Eisenberg, Edward M. Marcotte, Ioannis Xenarios and Todd O. Yeates

doi:10.1038/35015694

Abstract | Full Text | PDF (227K)

Genomics, gene expression and DNA arrays p827

David J. Lockhart and Elizabeth A. Winzeler

doi:10.1038/35015701

Abstract | Full Text | PDF (850K)

Proteomics to study genes and genomes p837

Akhilesh Pandey and Matthias Mann

doi:10.1038/35015709

Abstract | Full Text | PDF (475K)

Searching for genetic determinants in the new millennium p847

Neil J. Risch

doi:10.1038/35015718

Abstract | Full Text | PDF (190K)

Pharmacogenetics and the practice of medicine p857

Allen D. Roses

doi:10.1038/35015728

Abstract | Full Text | PDF (540K)

Aventis and functional genomics p866

doi:10.1038/35015736

Full Text | PDF (79K)

New on the Market

Electrophoresis for gels p867

Windows but no pain, doors but no entry, Watson but with Crick.

doi:10.1038/35015682

Full Text | PDF (196K)