Opinion

The limits of sharing p599

President Clinton's offer to share missile defence with his allies brings to mind his presidency's weaknesses — his fondness of fudge and reluctance to embrace unpopular truths.

doi:10.1038/35015212

Full Text | PDF (55K)

Gene therapy's trials p599

One major laboratory has closed because of a clinical trial's tragic outcome. But others need publicly to review their roles.

doi:10.1038/35015214

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News

Biologists challenge sequencers on parasite genome publication p601

Colin Macilwain

doi:10.1038/35015216

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New Russian science head named p601

Carl Levitin

doi:10.1038/35015220

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Drive for more genomes threatens mouse sequence p602

Alison Abbott

doi:10.1038/35015222

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Software spend boosts Israeli R&D p603

Haim Watzman

doi:10.1038/35015225

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Internet gateway planned for neuroinformatics data p603

Paul Smaglik

doi:10.1038/35015227

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Spain in quandary over French synchrotron p604

Xavier Bosch

doi:10.1038/35015230

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Immigrants help offset Canada's brain-drain crisis p604

David Spurgeon

doi:10.1038/35015234

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A slot in the dock predicted for the chemical industry p605

Natasha Loder

doi:10.1038/35015236

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Roche brings down curtain on Swiss immunology lab p605

Alison Abbott

doi:10.1038/35015238

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US decides close tabs must be kept on xenotransplants... p606

Declan Butler

doi:10.1038/35015241

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... and sets up a body to oversee trials p607

Paul Smaglik

doi:10.1038/35015244

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News in brief p608

doi:10.1038/35015246

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News Feature

Cloning's owners go to war p610

The team that created Dolly the sheep captured the headlines, but several groups now have patents on cloning. Peter Aldhous considers how this tangled web of proprietary claims will affect the future of the technology.

Peter Aldhous

doi:10.1038/35015249

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Paradise lost in Hawaii p612

doi:10.1038/35015255

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Correspondence

Regulation, not private enterprise, is the key to a healthy environment p613

George M. Woodwell

doi:10.1038/35015259

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England and US corner the journal market p613

A. A. Waheed

doi:10.1038/35015261

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Celera's role in opening up new frontiers p613

Ken Calvert

doi:10.1038/35015264

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Commentary

Climate change in perspective p615

Our concerns about global warming have an age-old resonance.

doi:10.1038/35015179

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Book Reviews

Skull and cross words p617

How the discovery of an ancient American skeleton set science against law.

Simon Conway Morris reviews Riddle of the Bones: Politics, Science, Race, and the Story of Kennewick Man by Roger Downey

doi:10.1038/35015148

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The quantum jungle revisited p618

Anton Zeilinger reviews The New World of Mr Tompkins by George Gamow and Russell Stannard

doi:10.1038/35015151

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Hands-on taxonomy p619

Henry Disney reviews Describing Species: Practical Taxonomic Procedure for Biologists by Judith E. Winston

doi:10.1038/35015154

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New in paperback p619

doi:10.1038/35015157

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The Wonderland of primordial life p619

John Godfrey reviews Life Without Genes by Adrian Woolfson

doi:10.1038/35015159

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Science in culture p620

Alison Abbott reviews

doi:10.1038/35015161

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Millennium Essay

Show them how it's really done p621

The public's appetite for science will not be whetted by a diet of dry facts.

Nancy J. Rothwell

doi:10.1038/35015181

Full Text | PDF (231K)

Futures

New ice age, or just cold feet? p623

Tempers boil over at a heated meeting on global cooling.

Norman Spinrad

doi:10.1038/35015184

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News and Views

Palaeobiology: The realms of Archaean life p625

There is evidence of a variety of early organisms from the Archaean — some 4,000 to 2,500 million years ago. Now life at deep-sea hot springs can provisionally be added to the list.

Euan Nisbet

doi:10.1038/35015187

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Materials chemistry: Semiconductors meet biology p626

Chad A. Mirkin and T. Andrew Taton

doi:10.1038/35015190

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Alzheimer's disease: Closing in on -secretase p627

Bart De Strooper

doi:10.1038/35015193

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Semiconductor physics: Half-matter, half-light amplifier p629

Yoshihisa Yamamoto

doi:10.1038/35015196

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100 and 50 years ago p630

doi:10.1038/35015199

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Laser-matter interactions: It takes two electrons to tango p631

Keith Burnett

doi:10.1038/35015201

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Biomechanics: Gripping feat p631

Henry Gee

doi:10.1038/35015203

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Structural biology: Pumping ions p633

David H. MacLennan and N. Michael Green

doi:10.1038/35015206

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Daedalus: Pumping a vacuum p634

David Jones

doi:10.1038/35015210

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Brief Communications

Recombinant erythropoietin in urine p635

An artificial hormone taken to boost athletic performance can now be detected.

Françoise Lasne and Jacques de Ceaurriz

doi:10.1038/35015164

First paragraph | Full Text | PDF (248K)

Phylogeny: Parabasalian flagellates are ancient eukaryotes p635

Patrick J. Keeling and Jeffrey D. Palmer

doi:10.1038/35015167

First paragraph | Full Text | PDF (248K)

Planetary science: Tectonics and water on Europa p637

Eric J. Gaidos and Francis Nimmo

doi:10.1038/35015170

First paragraph | Full Text | PDF (64K)

Review

Scalar turbulence p639

Boris I. Shraiman and Eric D. Siggia

doi:10.1038/35015000

Abstract | Full Text | PDF (338K)

Article

Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution p647

Chikashi Toyoshima, Masayoshi Nakasako, Hiromi Nomura and Haruo Ogawa

doi:10.1038/35015017

Abstract | Full Text | PDF (1,094K)

See also: News and Views by MacLennan & Green

Letters to Nature

Newly synthesized lithium in the interstellar medium p656

D. C. Knauth, S. R. Federman, David L. Lambert and P. Crane

doi:10.1038/35015028

First paragraph | Full Text | PDF (156K)

Correlated electron emission in multiphoton double ionization p658

Th. Weber, H. Giessen, M. Weckenbrock, G. Urbasch, A. Staudte, L. Spielberger, O. Jagutzki, V. Mergel, M. Vollmer and R. Dörner

doi:10.1038/35015033

First paragraph | Full Text | PDF (210K)

See also: News and Views by Burnett

Improving the performance of doped -conjugated polymers for use in organic light-emitting diodes p661

Markus Gross, David C. Müller, Heinz-Georg Nothofer, Ulrich Scherf, Dieter Neher, Christoph Bräuchle and Klaus Meerholz

doi:10.1038/35015037

First paragraph | Full Text | PDF (247K)

Selection of peptides with semiconductor binding specificity for directed nanocrystal assembly p665

Sandra R. Whaley, D. S. English, Evelyn L. Hu, Paul F. Barbara and Angela M. Belcher

doi:10.1038/35015043

First paragraph | Full Text | PDF (230K)

See also: News and Views by Mirkin & Taton

Reduced growth of Alaskan white spruce in the twentieth century from temperature-induced drought stress p668

Valerie A. Barber, Glenn Patrick Juday and Bruce P. Finney

doi:10.1038/35015049

First paragraph | Full Text | PDF (219K)

Isotopic evidence for Late Cretaceous plume–ridge interaction at the Hawaiian hotspot p673

Randall A. Keller, Martin R. Fisk and William M. White

doi:10.1038/35015057

First paragraph | Full Text | PDF (151K)

Filamentous microfossils in a 3,235-million-year-old volcanogenic massive sulphide deposit p676

Birger Rasmussen

doi:10.1038/35015063

First paragraph | Full Text | PDF (318K)

See also: News and Views by Nisbet

Parasite adaptation to locally common host genotypes p679

Curtis M. Lively and Mark F. Dybdahl

doi:10.1038/35015069

First paragraph | Full Text | PDF (119K)

Adhesive force of a single gecko foot-hair p681

Kellar Autumn, Yiching A. Liang, S. Tonia Hsieh, Wolfgang Zesch, Wai Pang Chan, Thomas W. Kenny, Ronald Fearing and Robert J. Full

doi:10.1038/35015073

First paragraph | Full Text | PDF (257K)

See also: News and Views by Gee

Neural synchrony correlates with surface segregation rules p685

Miguel Castelo-Branco, Rainer Goebel, Sergio Neuenschwander and Wolf Singer

doi:10.1038/35015079

First paragraph | Full Text | PDF (341K)

Photoactivated -secretase inhibitors directed to the active site covalently label presenilin 1 p689

Yue-Ming Li, Min Xu, Ming-Tain Lai, Qian Huang, José L. Castro, Jillian DiMuzio-Mower, Timothy Harrison, Colin Lellis, Alan Nadin, Joseph G. Neduvelil, R. Bruce Register, Mohinder K. Sardana, Mark S. Shearman, Adrian L. Smith, Xiao-Ping Shi, Kuo-Chang Yin, Jules A. Shafer and Stephen J. Gardell

doi:10.1038/35015085

First paragraph | Full Text | PDF (353K)

See also: News and Views by De Strooper

-Haemolysin of uropathogenic E. coli induces Ca ²⁺ oscillations in renal epithelial cells p694

Per Uhlén, Åsa Laestadius, Timo Jahnukainen, Tomas Söderblom, Fredrik Bäckhed, Gianni Celsi, Hjalmar Brismar, Staffan Normark, Anita Aperia and Agneta Richter-Dahlfors

doi:10.1038/35015091

First paragraph | Full Text | PDF (288K)

Frequent chromosomal translocations induced by DNA double-strand breaks p697

Christine Richardson and Maria Jasin

doi:10.1038/35015097

First paragraph | Full Text | PDF (209K)

Redundant roles for the TFIID and SAGA complexes in global transcription p701

Tong Ihn Lee, Helen C. Causton, Frank C. P. Holstege, Wu-Cheng Shen, Nancy Hannett, Ezra G. Jennings, Fred Winston, Michael R. Green and Richard A. Young

doi:10.1038/35015104

First paragraph | Full Text | PDF (170K) | Supplementary information

Effects of mechanical forces on maintenance and adaptation of form in trabecular bone p704

Rik Huiskes, Ronald Ruimerman, G. Harry van Lenthe and Jan D. Janssen

doi:10.1038/35015116

First paragraph | Full Text | PDF (215K)

Biological sensing of small field differences by magnetically sensitive chemical reactions p707

James C. Weaver, Timothy E. Vaughan and R. Dean Astumian

doi:10.1038/35015128

First paragraph | Full Text | PDF (162K)

New on the Market

More things to do with DNA p711

Blow air at it, heat it, extract it, repair it, spin it, amplify it, express it...

doi:10.1038/35015172

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Careers and Recruitment

US science shocked by revelations of sexual discrimination p713

The scientific establishment in the United States has received a resounding wake-up call over sexual equality. Natasha Loder investigates.

Natasha Loder

doi:10.1038/35015266

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Making moves to redress the gender imbalance p715

Helen Gavaghan

doi:10.1038/35015270

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New UK legislation aids fight against discrimination p716

Helen Gavaghan

doi:10.1038/35015274

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US minorities stake their claim in science and engineering p717

Potter Wickware

doi:10.1038/35015276

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Canadian aborigines get overlooked p717

Potter Wickware

doi:10.1038/35015279

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Access to education provides a way out p718

Potter Wickware

doi:10.1038/35015281

Full Text | PDF (99K)