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Nature 405, 408-409 (25 May 2000) | doi:10.1038/35013178
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Genomic imprinting: Silence across the border
Imprinted genes in mammals are expressed from only one chromosome: either the gene inherited from the mother or that from the father is silenced. Such genes include Igf2 and other genes involved in growth control; here, imprinting might work to balance maternal and paternal demands on the size of an embryo.
- Wolf Reik and Adele Murrell are in the Laboratory of Developmental Genetics and Imprinting, The Babraham Institute, Cambridge CB2 4AT, UK.
Correspondence to: Wolf Reik1 e-mail: Email: wolf.reik@bbsrc.ac.uk
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