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Genomic imprinting: Silence across the border

Wolf Reik1 & Adele Murrell1

Imprinted genes in mammals are expressed from only one chromosome: either the gene inherited from the mother or that from the father is silenced. Such genes include Igf2 and other genes involved in growth control; here, imprinting might work to balance maternal and paternal demands on the size of an embryo.

  1. Wolf Reik and Adele Murrell are in the Laboratory of Developmental Genetics and Imprinting, The Babraham Institute, Cambridge CB2 4AT, UK.

Correspondence to: Wolf Reik1 e-mail: Email: wolf.reik@bbsrc.ac.uk