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Review
Nature 405, 299-304 (18 May 2000) | doi:10.1038/35012500
Open Innovation Challenges
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Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
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Fast Growth of Transformed Soybean Shoots
A method for accelerating growth of soybean shoots is desired.
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Scientist with veterinary qualification
- Philip Morris International (PMI)
- Singapore
Postdoctoral Associate
- Thomas Jefferson University
- Philadelphia, Pennsylvannia, USA
Lateral gene transfer and the nature of bacterial innovation
Howard Ochman1, Jeffrey G. Lawrence2 & Eduardo A. Groisman3
Abstract
Unlike eukaryotes, which evolve principally through the modification of existing genetic information, bacteria have obtained a significant proportion of their genetic diversity through the acquisition of sequences from distantly related organisms. Horizontal gene transfer produces extremely dynamic genomes in which substantial amounts of DNA are introduced into and deleted from the chromosome. These lateral transfers have effectively changed the ecological and pathogenic character of bacterial species.
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