An open letter to the president of South Africa.
doi:10.1038/35010205
Table of contents
Volume 404 Number 6781 pp907-1021
Top of page
Opinion
Dear Mr Mbeki ... p907
Big can still be great p907
High-energy physicists in the United States need to take time to reach agreement on new goals.
doi:10.1038/35010207
Top of page
News
Budget crisis forces hard choices on US high-energy physics p909
UK science spend 'not sensible' p909
'Saturation screen' lets zebrafish show their stripes p910
Letter fuels South Africa's AIDS furore p911
Unesco backs 'science for debt' plan p911
Genetic diversity project fights for its life... p912
...as companies are urged to share benefits p912
NASA's new environmental satellite shows its sensitive side p913
Japan gears up for growth in genomics p913
New Zealand GM inquiry will cast a wide net p914
German research agency 'doesn't stifle creativity', say 1,600 scientists p915
Top of page
News Feature
Meet the spin doctors ... p918
A small band of researchers is plotting a revolution in electronics — one that exploits the spins of electrons, rather than their charges. Philip Ball profiles the emerging field of spintronics.
Philip Ball
doi:10.1038/35010132
Top of page
Correspondence
How diagnosis with microarrays can help cancer patients p921
Short-sighted move to close the 12-m telescope p921
Genetic modification and the meat market p921
Distinguished scientists back Germany's DFG... p922
...but young researchers feel disillusioned p922
reply: ...but young researchers feel disillusioned p922
Top of page
Commentary
'Marketing' species conservation p923
Financial incentives can be found to conserve a species threatened by trade.
R. E. Gullison, R. E. Rice and A. G. Blundell
doi:10.1038/35010151
Top of page
Spring Books
Sir James in cyberspace p925
Let there be public revelry — the OED takes to another dimension.
doi:10.1038/35010156
When silence is not a true option p926
doi:10.1038/35010159
Of science and men p927
doi:10.1038/35010162
Wacky star of the Renaissance p928
doi:10.1038/35010164
Not just a pretty Polly p929
doi:10.1038/35010167
Communications from the dead p930
doi:10.1038/35010170
On being human p931
doi:10.1038/35010173
The sequence of words p932
doi:10.1038/35010175
Evolution in a broader perspective p933
doi:10.1038/35010178
How much is really changing in Japan? p934
doi:10.1038/35010181
Top of page
Millennium Essay
Putting technology in its place p935
Why don't Europeans carry Mayan calendar calculators in their Filofaxes?
Don Ihde
doi:10.1038/35010184
Top of page
Futures
The Enduring Test p937
How long must you wait before proving your humanity?
Paul Levinson
doi:10.1038/35010187
Top of page
News and Views
天文学：新宇宙論に耳を澄ます
Ringing in the new cosmology p939
Balloon experiments over Antarctica have produced a long-awaited temperature map of the microwave sky. The map reveals sound waves that can be used to probe the early Universe.
Wayne Hu
doi:10.1038/35010242
分子生物学：イントロンが進出
Molecular biology: Introns gain ground p940
ナノ技術：極微の橋を渡る熱
Nanotechnology: Heat flow through nanobridges p943
ハンチントン病：時をさかのぼる
Huntington's disease: In reverse gear p944
情報伝達：脂質輸送の分子スイッチ
Signal transduction: Molecular switches in lipid rafts p945
量子工学：超伝導ナノワイヤー
Quantum engineering: Superconducting nanowires p948
自己免疫：B細胞を邪魔するおとり受容体
Autoimmunity: Decoy receptors thwart B cells p949
Daedalus: Danger! Men at work p950
Top of page
Brief Communications
Focusing hard X-rays with old LPs p951
A vinyl long-playing record can be used to form a cheap, aberration-free refractive lens.
Björn Cederström, Robert N. Cahn, Mats Danielsson, Mats Lundqvist and David R. Nygren
doi:10.1038/35010190
Evolution: Symbiotic solution to arsenic contamination p951
J. M. Sharples, A. A. Meharg, S. M. Chambers and J. W. G. Cairney
doi:10.1038/35010193
Pattern recognition: Tunes and templates p952
Palaeontology: A refugium for relicts? p953
Makoto Manabe, Paul M. Barrett and Shinji Isaji
doi:10.1038/35010199
Top of page
Articles
宇宙：宇宙マイクロ波背景放射の高分解能地図によれば宇宙は平坦
A flat Universe from high-resolution maps of the cosmic microwave background radiation p955
P. de Bernardis, P. A. R. Ade, J. J. Bock, J. R. Bond, J. Borrill, A. Boscaleri, K. Coble, B. P. Crill, G. De Gasperis, P. C. Farese, P. G. Ferreira, K. Ganga, M. Giacometti, E. Hivon, V. V. Hristov, A. Iacoangeli, A. H. Jaffe, A. E. Lange, L. Martinis, S. Masi, P. V. Mason, P. D. Mauskopf, A. Melchiorri, L. Miglio, T. Montroy, C. B. Netterfield, E. Pascale, F. Piacentini, D. Pogosyan, S. Prunet, S. Rao, G. Romeo, J. E. Ruhl, F. Scaramuzzi, D. Sforna and N. Vittorio
doi:10.1038/35010035
生化学：分解能3.6Åで得たレオウイルスのコアの構造
Structure of the reovirus core at 3.6 Å resolution p960
Karin M. Reinisch, Max L. Nibert and Stephen C. Harrison
doi:10.1038/35010041
日本語要約 | Full Text | PDF (894K)
Top of page
Low fidelity DNA synthesis by human DNA polymerase-
Letters to Nature
宇宙：惑星間塵微粒子中に分子雲物質を確認
Identification of molecular-cloud material in interplanetary dust particles p968
物性：超細ナノワイヤーにおける超伝導の量子的抑制
Quantum suppression of superconductivity in ultrathin nanowires p971
物性：熱コンダクタンスの量子の測定
Measurement of the quantum of thermal conductance p974
K. Schwab, E. A. Henriksen, J. M. Worlock and M. L. Roukes
doi:10.1038/35010065
日本語要約 | Full Text | PDF (233K)
材料：単結晶有機薄膜トランジスターにおけるクーロン妨害輸送
Coulomb-blockade transport in single-crystal organic thin-film transistors p977
W. A. Schoonveld, J. Wildeman, D. Fichou, P. A. Bobbert, B. J. van Wees and T. M. Klapwijk
doi:10.1038/35010073
日本語要約 | Full Text | PDF (229K)
材料：有毒金属を含まない無機黄色−赤色色素
Inorganic yellow-red pigments without toxic metals p980
材料：エナンチオ選択的分離と触媒に適した、ホモキラルな金属−有機物多孔質材料
A homochiral metal–organic porous material for enantioselective separation and catalysis p982
Jung Soo Seo, Dongmok Whang, Hyoyoung Lee, Sung Im Jun, Jinho Oh, Young Jin Jeon and Kimoon Kim
doi:10.1038/35010088
地球：マウナロア溶岩供給源中の「幽霊斜長石」に見られる再利用された海洋地殻
Recycled oceanic crust observed in 'ghost plagioclase' within the source of Mauna Loa lavas p986
Alexander V. Sobolev, Albrecht W. Hofmann and Igor K. Nikogosian
doi:10.1038/35010098
生態：生物多様性のホットスポットにおけるヒト個体群
Human population in the biodiversity hotspots p990
Richard P. Cincotta, Jennifer Wisnewski and Robert Engelman
doi:10.1038/35010105
日本語要約 | Full Text | PDF (775K)
生理：睡眠促進ニューロンの脳切片中での同定
Identification of sleep-promoting neurons in vitro p992
Thierry Gallopin, Patrice Fort, Emmanuel Eggermann, Bruno Cauli, Pierre-Hervé Luppi, Jean Rossier, Etienne Audinat, Michel Mühlethaler and Mauro Serafin
doi:10.1038/35010109
日本語要約 | Full Text | PDF (295K)
免疫：TACIとBCMAはB細胞性自己免疫疾患にかかわるTNF類似体の受容体である
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease p995
Jane A. Gross, Janet Johnston, Sherri Mudri, Rachel Enselman, Stacey R. Dillon, Karen Madden, Wenfeng Xu, Julia Parrish-Novak, Don Foster, Cathy Lofton-Day, Margaret Moore, Alisa Littau, Angelika Grossman, Harald Haugen, Kevin Foley, Hal Blumberg, Kim Harrison, Wayne Kindsvogel and Christopher H. Clegg
doi:10.1038/35010115
日本語要約 | Full Text | PDF (318K)
生理：膜貫通型リンタンパク質CbpがSrcファミリーのチロシンキナーゼの活性を調節する
Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases p999
Masahiro Kawabuchi, Yoshinori Satomi, Toshifumi Takao, Yasutsugu Shimonishi, Shigeyuki Nada, Katsuya Nagai, Alexander Tarakhovsky and Masato Okada
doi:10.1038/35010121
日本語要約 | Full Text | PDF (376K)
医学：DNMT1をもたないヒト癌細胞ではCpGのメチル化が維持される
CpG methylation is maintained in human cancer cells lacking DNMT1 p1003
Ina Rhee, Kam-Wing Jair, Ray-Whay Chiu Yen, Christoph Lengauer, James G. Herman, Kenneth W. Kinzler, Bert Vogelstein, Stephen B. Baylin and Kornel E. Schuebel
doi:10.1038/35010000
細胞：Arp2/3複合体とWASP/Scarタンパク質による樹状アクチンフィラメント網目構造の直接観察
Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins p1007
Laurent Blanchoin, Kurt J. Amann, Henry N. Higgs, Jean-Baptiste Marchand, Donald A. Kaiser and Thomas D. Pollard
doi:10.1038/35010008
日本語要約 | Full Text | PDF (311K)
細胞：ヒトDNAポリメラーゼhによる忠実度の低いDNA合成
Low fidelity DNA synthesis by human DNA polymerase-
p1011
Toshiro Matsuda, Katarzyna Bebenek, Chikahide Masutani, Fumio Hanaoka and Thomas A. Kunkel
doi:10.1038/35010014
日本語要約 | Full Text | PDF (136K)
細胞：大腸菌のDNAポリメラーゼIVとVが、損傷を標的とするあるいは標的としないSOS変異誘発に果たす役割
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis p1014
Mengjia Tang, Phuong Pham, Xuan Shen, John-Stephen Taylor, Mike O'Donnell, Roger Woodgate and Myron F. Goodman
doi:10.1038/35010020
日本語要約 | Full Text | PDF (356K)
細胞：細菌のグループIIイントロンのレトロ転位
Retrotransposition of a bacterial group II intron p1018
Benoit Cousineau, Stacey Lawrence, Dorie Smith and Marlene Belfort
doi:10.1038/35010029
日本語要約 | Full Text | PDF (231K)
