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Nature 404, 945-947 (27 April 2000) | doi:10.1038/35010257

Open Innovation Challenges

Signal transduction: Molecular switches in lipid rafts

Leslie A. Cary1 & Jonathan A. Cooper1

Cells do not exist in isolation from their external environment, and need to be able to modify their activity according to what is happening outside them. Molecular switches act to relay information from a cell's exterior to its interior.

  1. Leslie A. Cary and Jonathan A. Cooper are at the Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, PO Box 19024, Seattle, Washington 98109-1024 , USA.

Correspondence to: Jonathan A. Cooper1 e-mail: Email: jcooper@fred.fhcrc.org