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Nature 404, 135-137 (9 March 2000) | doi:10.1038/35004693

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Cell biology: Moving in mysterious ways

Alison M. Condliffe1 & Phillip T. Hawkins

In their mission to engulf and destroy invading microorganisms, certain white blood cells (leukocytes) must leave the blood stream and migrate to the sites of infection. Such cells track their targets by following increasing concentrations of chemoattractant molecules — chemotactic gradients — until at higher concentrations the engulfment response comes into operation.

  1. Alison M. Condliffe is in the Department of Medicine, University of Cambridge Clinical Medical School, Addenbrookes and Papworth Hospitals, Hills Road, Cambridge CB2 2QQ, UK.

Correspondence to: Phillip T. Hawkins Phillip T. Hawkins is at The Babraham Institute, Babraham, Cambridge CB2 4AT, UK.
e-mail: Email:  phillip.hawkins@bbsrc.ac.uk