FIGURE 4. Detecting three-dimensional patterns of deep nuclear tissue loss.
From the following article:
Growth patterns in the developing brain detected by using continuum mechanical tensor maps
Paul M. Thompson, Jay N. Giedd, Roger P. Woods, David MacDonald, Alan C. Evans and Arthur W. Toga
Nature 404, 190-193(9 March 2000)
doi:10.1038/35004593
a, b, Tensor maps distinguish local growth or brain tissue loss from global displacements (b) of the adjacent ventricular anatomy, modelled here (a) at ages 7 years (red) and 11 years (yellow). c, d, Between ages 7 and 11 years, three-dimensional displacement vector maps show the deformation required to reconfigure earlier models of the caudate head into their later shape. The caudate tail is stable (blue colours, d). e, f, Local growth (e) and anatomical displacement (d) of the caudate head are independently recovered, with 50% tissue loss detected locally (e, f), adjacent to a region of 20–30% growth throughout the internal capsule.