Table of contents
Volume 404 Number 6773 pp1-108
Opinion
Albright's last scientific stand p1
The US Secretary of State has announced some tentative steps towards the elusive goal of a scientifically literate State Department. Her successor will need to go further.
doi:10.1038/35003697
A critical nuclear appointment p1
The resignation of a chief executive poses a challenge for a profitable international company in desperate circumstances.
doi:10.1038/35003699
News
Germany challenges human stem cell patent awarded 'by mistake' p3
Quirin Schiermeier
doi:10.1038/35003701
UK university recruitment in danger p3
Natasha Loder
doi:10.1038/35003704
US energy agency pulls plug on role in genome project p4
Colin Macilwain
doi:10.1038/35003706
Australian jailed for removal of fossilized footprints p4
Peter Pockley
doi:10.1038/35003708
NIH tightens up monitoring of gene-therapy mishaps p5
Paul Smaglik
doi:10.1038/35003711
Culling plans put future of red deer study in jeopardy p5
Natasha Loder
doi:10.1038/35003714
Young, worldly and unhelpful all miss out on data sharing p6
Rex Dalton
doi:10.1038/35003717
US eases Israelis' lab access p6
Haim Watzman
doi:10.1038/35003720
Promega and Roche take up battle over PCR patents p7
Rex Dalton
doi:10.1038/35003722
Funding woes spell doom for US radio dish p7
Tony Reichhardt
doi:10.1038/35003724
Canadian budget boost for science p8
David Spurgeon
doi:10.1038/35003727
Robert May to head Royal Society p8
doi:10.1038/35003729
Post-Cold War needs 'new forms of scientific linkage' p8
Heather McCabe
doi:10.1038/35003731
News Analysis
Analysis of polio vaccine could end dispute over how AIDS originated p9
Could an effort to rid Africa of polio have caused the AIDS pandemic? While labs prepare to test the vaccine, researchers are at war over the theory.
Declan Butler
doi:10.1038/35003734
Correspondence
Crowded universities cramp more than just students' style p13
Akio Yamamoto
doi:10.1038/35003739
Patent confusion in law on new plant varieties p13
John R. Porter
doi:10.1038/35003742
Book Reviews
Evolution rising from the grave p15
Reactivation of a dormant message signals the dawn of a new humanity.
Michael A. Goldman reviews Darwin's Radio by Greg Bear
doi:10.1038/35003625
Buried in their thousands p15
doi:10.1038/35003627
Around the world via Greenwich p16
J.L. Heilbron reviews Globes at Greenwich: A Catalogue of the Globes and Armillary Spheres at the National Maritime Museum
doi:10.1038/35003630
A window on scientific progress p17
Gunhard Æ. Oravas reviews Science and Technology in World History: An Introduction by James E. McClellan, III and Harold Dorn
doi:10.1038/35003633
Science in culture p18
John Whitfield reviews
doi:10.1038/35003636
Millennium Essay
Reversing Rorschach p19
Ink-blot tests might be able to tell us more about creativity than personality.
Richard Gregory
doi:10.1038/35003661
Futures
Danger — hard hack area p21
"Sequence your genome at home, and set science free!" cry the biopunks.
Paul McAuley
doi:10.1038/35003664
News and Views
Climatology: Of ice and elephants p23
What caused the great ice ages? Accurate dating of the end of one of these ice ages makes us reconsider which part of the climate system drives severe glaciation.
Daniel P. Schrag
doi:10.1038/35003667
Cancer: p53 sends nucleotides to repair DNA p24
Guillermina Lozano and Stephen J. Elledge
doi:10.1038/35003670
Circadian clocks: Heartfelt enlightenment p25
Ueli Schibler
doi:10.1038/35003674
100 and 50 years ago p27
doi:10.1038/35003677
Physics: Brane new worlds p28
Jerome Gauntlett
doi:10.1038/35003679
Cognitive neuroscience: Imaging in the fourth dimension p29
Thomas Elbert and Andreas Keil
doi:10.1038/35003682
Animal biology: Beauty is ova-rated p31
Rachel Smyly
doi:10.1038/35003685
Planetary science: Brimstone on Mars p32
Harry Y. McSween, Jr
doi:10.1038/35003688
Daedalus: Brief lives p32
David Jones
doi:10.1038/35003691
Brief Communications
Errors in judging 'offside' in football p33
Optical trickery can undermine the assistant referee's view of this ruling.
Raôul R. D. Oudejans, Raymond Verheijen, Frank C. Bakker, Jeroen C. Gerrits, Marten Steinbrückner and Peter J. Beek
doi:10.1038/35003639
First paragraph | Full Text | PDF (104K)
Bioinformatics: Finding genes in Plasmodium falciparum p34
Mihaela Pertea, Steven L. Salzberg and Malcolm J. Gardner
doi:10.1038/35003643
First paragraph | Full Text | PDF (116K)
Bioinformatics: Finding genes in Plasmodium falciparum p34
Dan Lawson, Sharen Bowman and Bart Barrell
doi:10.1038/35003646
First paragraph | Full Text | PDF (116K)
Oceanography: Fish do not avoid survey vessels p35
P. G. Fernandes, A. S. Brierley, E. J. Simmonds, N. W. Millard, S. D. McPhail, F. Armstrong, P. Stevenson and M. Squires
doi:10.1038/35003648
First paragraph | Full Text | PDF (201K)
Evolution: Migration and speciation p36
Kevin Winker
doi:10.1038/35003651
First paragraph | Full Text | PDF (176K)
Correction: Arsenic poisoning in the Ganges delta p36
doi:10.1038/35003654
First paragraph | Full Text | PDF (176K)
Progress
The importance of repairing stalled replication forks p37
Michael M. Cox, Myron F. Goodman, Kenneth N. Kreuzer, David J. Sherratt, Steven J. Sandler and Kenneth J. Marians
doi:10.1038/35003501
Abstract | Full Text | PDF (204K)
Article
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage p42
Hiroshi Tanaka, Hirofumi Arakawa, Tatsuya Yamaguchi, Kenji Shiraishi, Seisuke Fukuda, Kuniko Matsui, Yoshiki Takei and Yusuke Nakamura
doi:10.1038/35003506
Abstract | Full Text | PDF (660K)
See also: News and Views by Lozano & Elledge
Letters to Nature
Evidence of atmospheric sulphur in the martian regolith from sulphur isotopes in meteorites p50
James Farquhar, Joel Savarino, Terri L. Jackson and Mark H. Thiemens
doi:10.1038/35003517
First paragraph | Full Text | PDF (243K)
See also: News and Views by McSween
Fabrication of photonic crystals for the visible spectrum by holographic lithography p53
M. Campbell, D. N. Sharp, M. T. Harrison, R. G. Denning and A. J. Turberfield
doi:10.1038/35003523
First paragraph | Full Text | PDF (326K)
Electrophoretic assembly of colloidal crystals with optically tunable micropatterns p56
R. C. Hayward, D. A. Saville and I. A. Aksay
doi:10.1038/35003530
First paragraph | Full Text | PDF (630K)
Shape control of CdSe nanocrystals p59
Xiaogang Peng, Liberato Manna, Weidong Yang, Juanita Wickham, Erik Scher, Andreas Kadavanich and A. P. Alivisatos
doi:10.1038/35003535
First paragraph | Full Text | PDF (573K)
Evidence from U–Th dating against Northern Hemisphere forcing of the penultimate deglaciation p61
Gideon M. Henderson and Niall C. Slowey
doi:10.1038/35003541
First paragraph | Full Text | PDF (486K)
See also: News and Views by Schrag
Stable sulphate clusters as a source of new atmospheric particles p66
Markku Kulmala, Liisa Pirjola and Jyrki M. Mäkelä
doi:10.1038/35003550
First paragraph | Full Text | PDF (4,976K)
Geodetic evidence for a low slip rate in the Altyn Tagh fault system p69
Rebecca Bendick, Roger Bilham, Jeffrey Freymueller, Kristine Larson and Guanghua Yin
doi:10.1038/35003555
First paragraph | Full Text | PDF (361K)
Tree species impoverishment and the future flora of the Atlantic forest of northeast Brazil p72
José Maria Cardoso da Silva and Marcelo Tabarelli
doi:10.1038/35003563
First paragraph | Full Text | PDF (161K) | Supplementary information
Egg investment is influenced by male attractiveness in the mallard p74
Emma J. A. Cunningham and Andrew F. Russell
doi:10.1038/35003565
First paragraph | Full Text | PDF (266K)
See also: News and Views by Smyly
Macaque monkeys categorize images by their ordinal number p77
Tanya Orlov, Volodya Yakovlev, Shaul Hochstein and Ehud Zohary
doi:10.1038/35003571
First paragraph | Full Text | PDF (394K)
Temporal patterns of human cortical activity reflect tone sequence structure p80
Aniruddh D. Patel and Evan Balaban
doi:10.1038/35003577
First paragraph | Full Text | PDF (836K) | Supplementary information
See also: News and Views by Elbert & Keil
Cannabinoids control spasticity and tremor in a multiple sclerosis model p84
David Baker, Gareth Pryce, J. Ludovic Croxford, Peter Brown, Roger G. Pertwee, John W. Huffman and Lorna Layward
doi:10.1038/35003583
First paragraph | Full Text | PDF (370K)
Light acts directly on organs and cells in culture to set the vertebrate circadian clock p87
David Whitmore, Nicholas S. Foulkes and Paolo Sassone-Corsi
doi:10.1038/35003589
First paragraph | Full Text | PDF (468K)
See also: News and Views by Schibler
Delayed activation of the paternal genome during seed development p91
Jean-Philippe Vielle-Calzada, Ramamurthy Baskar and Ueli Grossniklaus
doi:10.1038/35003595
First paragraph | Full Text | PDF (360K)
Eomesodermin is required for mouse trophoblast development and mesoderm formation p95
Andreas P. Russ, Sigrid Wattler, William H. Colledge, Samuel A. J. R. Aparicio, Mark B. L. Carlton, Jonathan J. Pearce, Sheila C. Barton, M. Azim Surani, Kenneth Ryan, Michael C. Nehls, Valerie Wilson and Martin J. Evans
doi:10.1038/35003601
First paragraph | Full Text | PDF (438K)
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours p99
Annie Yang, Nancy Walker, Roderick Bronson, Mourad Kaghad, Mariette Oosterwegel, Jacques Bonnin, Christine Vagner, Helene Bonnet, Pieter Dikkes, Arlene Sharpe, Frank McKeon and Daniel Caput
doi:10.1038/35003607
First paragraph | Full Text | PDF (1,615K)
Single-molecule studies of the effect of template tension on T7 DNA polymerase activity p103
Gijs J.L. Wuite, Steven B. Smith, Mark Young, David Keller and Carlos Bustamante
doi:10.1038/35003614
First paragraph | Full Text | PDF (1,000K)
New on the Market
Equipped for the purpose p107
A trawl through general laboratory equipment.
doi:10.1038/35003656
