FIGURE 4. Treatment of spasticity in autoimmune encephalomyelitis1 with non-CB1 receptor agonists.
From the following article:
Cannabinoids control spasticity and tremor in a multiple sclerosis model
David Baker, Gareth Pryce, J. Ludovic Croxford, Peter Brown, Roger G. Pertwee, John W. Huffman and Lorna Layward
Nature 404, 84-87(2 March 2000)
doi:10.1038/35003583
Forces (mean 
s.e.m.) required to flex individual spastic
hindlimbs against a strain gauge after i.v. injection with either low-dose
methanandamide (n = 9 limbs), JWH-133 (
n = 9) or palmitoylethanolamide (n = 14).
Asterisk, P < 0.05; two asterisks,
P < 0.001 compared with baseline.