Opinion

Hollow apologies should be avoided p813

The head of the Max Planck Society is right to resist pressures to apologize for the actions of a previous generation. But acknowledgement and condemnation cannot come too soon.

doi:10.1038/35002731

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News

Celera in talks to launch private sector human proteome project p815

Declan Butler

doi:10.1038/35002733

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Eros begins to yield up its secrets p815

Tony Reichhardt

doi:10.1038/35002736

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Biomedical centre memorial to victims of Nazi research p816

Patrick Weydt

doi:10.1038/35002739

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Australian industry 'starving' R&D p816

Peter Pockley

doi:10.1038/35002741

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Merck blocks 'safer' gene therapy trials p817

Paul Smaglik

doi:10.1038/35002743

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Celera's shotgun approach puts Drosophila in the bag p817

Natasha Loder

doi:10.1038/35002745

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Med school to relax rules on business links? p818

Steve Nadis

doi:10.1038/35002748

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Spanish boost for young scientists p818

Xavier Bosch

doi:10.1038/35002751

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AAAS members fret over links with theological foundation p819

Colin Macilwain

doi:10.1038/35002753

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Japan set to tighten ethics rules for genetic sampling p819

Robert Triendl

doi:10.1038/35002756

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Gene therapy institute denies that errors led to trial death p820

Paul Smaglik

doi:10.1038/35002758

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US physics society puts feisty newsletter in doubt p820

Colin Macilwain

doi:10.1038/35002761

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Germany holds up cultivation of GM maize... p821

Alison Abbott

doi:10.1038/35002763

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... amid calls for international biotech panel p821

David Dickson

doi:10.1038/35002766

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news in brief p822

doi:10.1038/35002768

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Correspondence

Open annotation offers a democratic solution to genome sequencing p825

Tim Hubbard and Ewan Birney

doi:10.1038/35002770

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Affirmative action won't solve sex discrimination p825

G.A. Lozano

doi:10.1038/35002772

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Why Roche deserves the disputed Taq patent p825

T. J. White

doi:10.1038/35002774

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ECT has proved effective in treating depression... p826

Max Fink

doi:10.1038/35002776

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... and there's no proof of lasting brain damage p826

Richard Abrams

doi:10.1038/35002778

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Shrinking shrews p826

D.W. Yalden

doi:10.1038/35002780

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Cloning shock: was Dolly a three-legged accident? p826

Wendy Gibson

doi:10.1038/35002782

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Book Reviews

A picaresque genius p827

Contribution of a flamboyant scientist, businessman and self-aggrandizer.

Gunther S. Stent reviews Félix d'Herelle and the Origins of Molecular Biology by William C. Summers

doi:10.1038/35002647

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Enter the cosmic cathedral p828

P. M. Solomon reviews

doi:10.1038/35002651

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India's fruitful tryst with technology p829

V.S. Arunachalam reviews Innovative India

doi:10.1038/35002654

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Science in culture p830

Douglas Palmer reviews

doi:10.1038/35002657

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Millennium Essay

Fighting the wrong battle p831

Scientists who scoff at religious belief miss the point and damage their cause.

Geoffrey Cantor

doi:10.1038/35002681

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Futures

Avatars in space p833

Why bother to colonize space when electronic devices do it so much better?

Geoffrey A. Landis

doi:10.1038/35002684

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News and Views

Structural Biology: Proteomics for the pore p835

The nuclear pore complex is the gateway that regulates two-way traffic between the nucleus and the rest of the cell. The architecture of this huge structure is now revealed in unprecedented detail.

Günter Blobel and Richard W. Wozniak

doi:10.1038/35002687

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Crystal structure: As weird as they come p836

Volker Heine

doi:10.1038/35002691

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Neurobiology: Tepid tastes p837

Robert A. Frank

doi:10.1038/35002694

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Earth science: A shear pathway to the core p839

Michael J. Walter

doi:10.1038/35002698

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100 and 50 years ago p840

doi:10.1038/35002700

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Plant biology: A social stigma p840

Teh-hui Kao and Andrew G. McCubbin

doi:10.1038/35002702

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Astronomy: Galaxy formation in action p841

Gary Welch

doi:10.1038/35002705

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Biodiversity: Extinction by numbers p843

Stuart L. Pimm and Peter Raven

doi:10.1038/35002708

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Laser physics: Attosecond pulses at last p845

Paul Corkum

doi:10.1038/35002711

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Neurobiology: Neurofibromin progress on the fly p846

Ronald L. Davis

doi:10.1038/35002714

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Volcanology: The bulge of Casita p846

Tim Lincoln

doi:10.1038/35002717

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Daedalus: Grinding waste away p847

David Jones

doi:10.1038/35002720

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Obituary: Paul Sigler (1934–2000) p848

Brian W. Matthews

doi:10.1038/35002722

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Brief Communications

Self-organizing processes: The sound of many hands clapping p849

Tumultuous applause can transform itself into waves of synchronized clapping.

Z. Néda, E. Ravasz, Y. Brechet, T. Vicsek and A.-L. Barabási

doi:10.1038/35002660

First paragraph | Full Text | PDF (134K)

Hormones: Leptin and diabetes in lipoatrophic mice p850

Oksana Gavrilova, Bernice Marcus-Samuels, Lisa R. Leon, Charles Vinson and Marc L. Reitman

doi:10.1038/35002663

First paragraph | Full Text | PDF (115K)

reply: Leptin and diabetes in lipoatrophic mice p850

Iichiro Shimomura, Robert E. Hammer, Shinji Ikemoto, Michael S. Brown and Joseph L. Goldstein

doi:10.1038/35002667

First paragraph | Full Text | PDF (115K)

Pheromones: Exploitation of gut bacteria in the locust p851

Rod J. Dillon, Chris T. Vennard and A. Keith Charnley

doi:10.1038/35002669

First paragraph | Full Text | PDF (136K)

Pollution: Recovery of breeding success in wild birds p851

Tapio Eeva and Esa Lehikoinen

doi:10.1038/35002672

First paragraph | Full Text | PDF (136K)

Articles

Biodiversity hotspots for conservation priorities p853

Norman Myers, Russell A. Mittermeier, Cristina G. Mittermeier, Gustavo A. B. da Fonseca and Jennifer Kent

doi:10.1038/35002501

Abstract | Full Text | PDF (266K) | Supplementary information

See also: News and Views by Pimm & Raven

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA p859

Steven D. Bruner, Derek P. G. Norman and Gregory L. Verdine

doi:10.1038/35002510

Abstract | Full Text | PDF (763K)

Letters to Nature

Formation of molecular gas in the tidal debris of violent galaxy–galaxy interactions p867

Jonathan Braine, Ute Lisenfeld, Pierre-Alain Due and Stéphane Leon

doi:10.1038/35002521

First paragraph | Full Text | PDF (453K)

See also: News and Views by Welch

Geometric quantum computation using nuclear magnetic resonance p869

Jonathan A. Jones, Vlatko Vedral, Artur Ekert and Giuseppe Castagnoli

doi:10.1038/35002528

First paragraph | Full Text | PDF (190K)

Reduction in the surface energy of liquid interfaces at short length scales p871

C. Fradin, A. Braslau, D. Luzet, D. Smilgies, M. Alba, N. Boudet, K. Mecke and J. Daillant

doi:10.1038/35002533

First paragraph | Full Text | PDF (298K)

Electrically induced structure formation and pattern transfer p874

Erik Schäffer, Thomas Thurn-Albrecht, Thomas P. Russell and Ullrich Steiner

doi:10.1038/35002540

First paragraph | Full Text | PDF (383K)

Variations of Younger Dryas atmospheric radiocarbon explicable without ocean circulation changes p877

Tomasz Goslar, Maurice Arnold, Nadine Tisnerat-Laborde, Justyna Czernik and Kazimierz Wickowski

doi:10.1038/35002547

First paragraph | Full Text | PDF (398K) | Supplementary information

A thermodynamic explanation for black smoker temperatures p880

Tim Jupp and Adam Schultz

doi:10.1038/35002552

First paragraph | Full Text | PDF (348K)

An interconnected network of core-forming melts produced by shear deformation p883

D. Bruhn, N. Groebner and D. L. Kohlstedt

doi:10.1038/35002558

First paragraph | Full Text | PDF (271K)

See also: News and Views by Walter

Rapid evolution of reproductive barriers driven by sexual conflict p886

Sergey Gavrilets

doi:10.1038/35002564

First paragraph | Full Text | PDF (242K) | Supplementary information

Thermal stimulation of taste p889

Alberto Cruz and Barry G. Green

doi:10.1038/35002581

First paragraph | Full Text | PDF (325K)

See also: News and Views by Frank

Postsaccadic visual references generate presaccadic compression of space p892

Markus Lappe, Holger Awater and Bart Krekelberg

doi:10.1038/35002588

First paragraph | Full Text | PDF (291K)

A neurofibromatosis-1-regulated pathway is required for learning in Drosophila p895

Hui-Fu Guo, Jiayuan Tong, Frances Hannan, Lin Luo and Yi Zhong

doi:10.1038/35002593

First paragraph | Full Text | PDF (382K)

See also: News and Views by Davis

Three distinct and sequential steps in the release of sodium ions by the Na⁺/K⁺-ATPase p898

Miguel Holmgren, Jonathan Wagg, Francisco Bezanilla, Robert F. Rakowski, Paul De Weer and David C. Gadsby

doi:10.1038/35002599

First paragraph | Full Text | PDF (374K)

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans p901

Brenda J. Reinhart, Frank J. Slack, Michael Basson, Amy E. Pasquinelli, Jill C. Bettinger, Ann E. Rougvie, H. Robert Horvitz and Gary Ruvkun

doi:10.1038/35002607

First paragraph | Full Text | PDF (416K)

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum p906

Michael B. Reed, Kevin J. Saliba, Sonia R. Caruana, Kiaran Kirk and Alan F. Cowman

doi:10.1038/35002615

First paragraph | Full Text | PDF (400K)

The LIM homeobox gene Lhx9 is essential for mouse gonad formation p909

Ohad S. Birk, Delane E. Casiano, Christopher A. Wassif, Tiziana Cogliati, Liping Zhao, Yangu Zhao, Alexander Grinberg, SingPing Huang, Jordan A. Kreidberg, Keith L. Parker, Forbes D. Porter and Heiner Westphal

doi:10.1038/35002622

First paragraph | Full Text | PDF (534K)

The S receptor kinase determines self-incompatibility in Brassica stigma p913

Takeshi Takasaki, Katsunori Hatakeyama, Go Suzuki, Masao Watanabe, Akira Isogai and Kokichi Hinata

doi:10.1038/35002628

First paragraph | Full Text | PDF (307K)

See also: News and Views by Kao & McCubbin

Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding p916

Ketan S. Gajiwala, Hua Chen, Fabrice Cornille, Bernard P. Roques, Walter Reith, Bernard Mach and Stephen K. Burley

doi:10.1038/35002634

First paragraph | Full Text | PDF (504K)

Structure of a ligand-binding intermediate in wild-type carbonmonoxy myoglobin p921

Kelvin Chu, Jaroslav Vojtchovský, Benjamin H. McMahon, Robert M. Sweet, Joel Berendzen and Ilme Schlichting

doi:10.1038/35002641

First paragraph | Full Text | PDF (218K)

New on the Market

The heat of the moment p925

Thermocyclers, and other manipulators and recorders of temperature.

doi:10.1038/35002676

Full Text | PDF (223K)