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Nature 403, 846-847 (24 February 2000) | doi:10.1038/35002714

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Neurobiology: Neurofibromin progress on the fly

Ronald L. Davis

One in every 3,500 individuals suffers from the genetic disease neurofibromatosis type 1 (NF1). The many symptoms of the disease, including tumours of the nervous system1, 2, result from a deficiency in the protein neurofibromin.