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Correspondence
Nature 403, 591-592 (10 February 2000) | doi:10.1038/35001230
Proteins suggest form of their own database
Marvin Cassman1, Tony Hunter2 & Tony Pawson3
- National Institute of General Medical Sciences, National Institutes of Health, Bldg 45, 2AN12B, Bethesda, Maryland 20892, USA.
- Salk Institute, 10010 North Torrey Pines, La Jolla, California 92037, USA
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada
A recent News report in Nature1 mentioned a workshop that we organized at the National Institutes of Health concerning the prospects for databases that describe signal transduction pathways, and more specifically that define protein–protein interactions.The complete genomic DNA sequence of an organism in principle yields its full coding potential, and gives the possibility of describing in a comprehensive fashion the structures and functions of proteins, and their organization into the pathways and networks that control cellular behaviour2.
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