Table of contents
Volume 403 Number 6768 pp345-466
Opinion
Can biological phenomena be understood by humans? p345
Despite the increasingly successful collaboration between physics and biology, there are contexts in which their styles and philosophies can diverge. Nowhere more so than in 'understanding'.
doi:10.1038/35000353
News
All parties keen to press on with Europe-based science website p347
Declan Butler
doi:10.1038/35000355
Quality, not quantity, for UK PhDs? p347
Natasha Loder
doi:10.1038/35000360
Clinton proposes $2.8 billion increase in science funding p349
Rex Dalton
doi:10.1038/35000362
Yale hopes a $500 million boost will raise research profile p349
Paul Smaglik
doi:10.1038/35000365
NIH cancer researchers to get free access to 'OncoMouse' p350
Paul Smaglik
doi:10.1038/35000368
Canadian biomedical collaboration keeps on growing p350
David Spurgeon
doi:10.1038/35000371
Ministries cooperate to plan Japanese genome centre p351
David Cyrano
doi:10.1038/35000373
Top physicist quits Japan for US p351
Robert Triendl
doi:10.1038/35000375
Issue of patents on 'Dolly' technology stirs controversy p351
Meredith Wadman
doi:10.1038/35000378
US survey reveals location of human tissue samples p352
Colin Macilwain
doi:10.1038/35000381
India targets extra research funds p352
K. S. Jayaraman
doi:10.1038/35000384
Head of US watchdog faces uncertain future p353
Meredith Wadman
doi:10.1038/35000386
Top UK epidemiologist suspended after complaints p353
Natasha Loder
doi:10.1038/35000388
Correspondence
Cell contamination leads to inaccurate data: we must take action now p356
G. N. Stacey
doi:10.1038/35000394
Mitchell saw the new vista, if not the details p356
Bo G. Malmström
doi:10.1038/35000396
Give credit where it's due (not to me, this time) p356
Reed B. Wickner
doi:10.1038/35000398
Commentary
Science moves to centre stage p357
Science is playing an increasing part in many decisions made by the UK Parliament, and probably in other legislation. What are the implications?
doi:10.1038/35000299
Book Reviews
Instincts for the past tense p361
Does the structure of the English language reflect the structure of the mind?
David Poeppel reviews Words and Rules: The Ingredients of Language by Steven Pinker
doi:10.1038/35000265
A world of silent communication p361
doi:10.1038/35000267
Why not knot right? p362
Gregory Buck reviews The 85 Ways to Tie a Tie: The Science and Aesthetics of Tie Knots by Thomas Fink and Yong Mao
doi:10.1038/35000270
Powering the planet p363
Michael Grätzel reviews From Space to Earth: The Story of Solar Electricity by John Perlin
doi:10.1038/35000273
An evolutionary odyssey p363
Jean-Jacques Hublin reviews The Human Career: Human Biological and Cultural Origins (second edition) by Richard G. Klein
doi:10.1038/35000276
Science in culture p364
Martin Kemp reviews
doi:10.1038/35000278
Millennium Essay
New approaches to old age p365
To truly understand ageing, we must look beyond the diseases of old age.
Leonard Hayflick
doi:10.1038/35000303
Futures
Pluto story p367
The discovery of extraterrestrial life was the key event of the third millennium.
Robert Silverberg
doi:10.1038/35000306
News and Views
Neurobiology: Nogo in nerve regeneration p369
A protein long thought to inhibit the growth of regenerating nerve axons has at last been identified and cloned. This discovery could be an important step towards promoting nerve regeneration after stroke or spinal-cord injury.
J. L. Goldberg and B. A. Barres
doi:10.1038/35000309
Palaeoclimatology: Out of Africa p370
Frank Oldfield
doi:10.1038/35000313
Photosynthesis: Harvesting sunlight safely p371
Barbara Demmig-Adams and William W. Adams, III
doi:10.1038/35000315
Citation analysis: Democracy on the rocks p373
Bruce W. D. Yardley
doi:10.1038/35000319
Nanotechnology: One photon seen by one electron p374
Leo Kouwenhoven
doi:10.1038/35000322
Global change: Rice, microbes and methane p375
Joshua Schimel
doi:10.1038/35000325
100 and 50 years ago p375
doi:10.1038/35000328
Fluid mechanics: Jets from a singular surface p377
Michael P. Brenner
doi:10.1038/35000330
Intelligence: Evolutionary psychology meets g p378
N. J. Mackintosh
doi:10.1038/35000333
Earth science: Volcanic action at Axial Seamount p379
Earl Davis
doi:10.1038/35000335
Daedalus: No more feelings p380
David Jones
doi:10.1038/35000339
Brief Communications
Energy for microbial life on Europa p381
A radiation-driven ecosystem on Jupiter's moon is not beyond the bounds of possibility.
Christopher F. Chyba
doi:10.1038/35000281
First paragraph | Full Text | PDF (183K)
Physiology: A function for guttural pouches in the horse p382
Keith E. Baptiste, Jonathan M. Naylor, Jeremy Bailey, Ernest M. Barber, Klass Post and Jim Thornhill
doi:10.1038/35000284
First paragraph | Full Text | PDF (495K)
Neurobiology: Inhibitor of neurite outgrowth in humans p383
Rabinder Prinjha, Stephen E. Moore, Mary Vinson, Sian Blake, Rachel Morrow, Gary Christie, David Michalovich, David L. Simmons and Frank S. Walsh
doi:10.1038/35000287
First paragraph | Full Text | PDF (611K) | Supplementary information
See also: News and Views by Goldberg & Barres
Materials: Creating the narrowest carbon nanotubes p384
L. F. Sun, S. S. Xie, W. Liu, W. Y. Zhou, Z. Q. Liu, D. S. Tang, G. Wang and L. X. Qian
doi:10.1038/35000290
First paragraph | Full Text | PDF (240K)
Progress
Nodal signalling in vertebrate development p385
Alexander F. Schier and Michael M. Shen
doi:10.1038/35000126
Abstract | Full Text | PDF (252K)
Article
A pigment-binding protein essential for regulation of photosynthetic light harvesting p391
Xiao-Ping Li, Olle Björkman, Connie Shih, Arthur R. Grossman, Magnus Rosenquist, Stefan Jansson and Krishna K. Niyogi
doi:10.1038/35000131
Abstract | Full Text | PDF (610K)
See also: News and Views by Demmig-Adams & Adams
Letters to Nature
Probing bulk states of correlated electron systems by high-resolution resonance photoemission p396
A. Sekiyama, T. Iwasaki, K. Matsuda, Y. Saitoh, Y. Ônuki and S. Suga
doi:10.1038/35000140
First paragraph | Full Text | PDF (483K)
Dynamic instabilities and memory effects in vortex matter p398
Y. Paltiel, E. Zeldov, Y. N. Myasoedov, H. Shtrikman, S. Bhattacharya, M. J. Higgins, Z. L. Xiao, E. Y. Andrei, P. L. Gammel and D. J. Bishop
doi:10.1038/35000145
First paragraph | Full Text | PDF (795K)
Singularity dynamics in curvature collapse and jet eruption on a fluid surface p401
Benjamin W. Zeff, Benjamin Kleber, Jay Fineberg and Daniel P. Lathrop
doi:10.1038/35000151
First paragraph | Full Text | PDF (1,036K)
See also: News and Views by Brenner
A single-photon detector in the far-infrared range p405
S. Komiyama, O. Astafiev, V. Antonov, T. Kutsuwa and H. Hirai
doi:10.1038/35000166
First paragraph | Full Text | PDF (248K)
See also: News and Views by Kouwenhoven
Efficient organic photovoltaic diodes based on doped pentacene p408
J. H. Schön, Ch. Kloc, E. Bucher and B. Batlogg
doi:10.1038/35000172
First paragraph | Full Text | PDF (332K)
Rainfall and drought in equatorial east Africa during the past 1,100 years p410
Dirk Verschuren, Kathleen R. Laird and Brian F. Cumming
doi:10.1038/35000179
First paragraph | Full Text | PDF (358K) | Supplementary information
See also: News and Views by Oldfield
Precise climate monitoring using complementary satellite data sets p414
Frank J. Wentz and Matthias Schabel
doi:10.1038/35000184
First paragraph | Full Text | PDF (183K)
The Pleistocene serpent Wonambi and the early evolution of snakes p416
John D. Scanlon and Michael S. Y. Lee
doi:10.1038/35000188
First paragraph | Full Text | PDF (509K) | Supplementary information
Stimulation by ammonium-based fertilizers of methane oxidation in soil around rice roots p421
Paul L. E. Bodelier, Peter Roslev, Thilo Henckel and Peter Frenzel
doi:10.1038/35000193
First paragraph | Full Text | PDF (270K)
See also: News and Views by Schimel
Activin- and Nodal-related factors control antero–posterior patterning of the zebrafish embryo p425
Bernard Thisse, Christopher V. E. Wright and Christine Thisse
doi:10.1038/35000200
First paragraph | Full Text | PDF (343K)
Separable processing of consonants and vowels p428
Alfonso Caramazza, Doriana Chialant, Rita Capasso and Gabriele Miceli
doi:10.1038/35000206
First paragraph | Full Text | PDF (159K)
Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion p430
J. M. Delfs, Y. Zhu, J. P. Druhan and G. Aston-Jones
doi:10.1038/35000212
First paragraph | Full Text | PDF (415K)
Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1 p434
Maio S. Chen, Andrea B. Huber, Marjan E. van der Haar, Marcus Frank, Lisa Schnell, Adrian A. Spillmann, Franziska Christ and Martin E. Schwab
doi:10.1038/35000219
First paragraph | Full Text | PDF (668K)
See also: News and Views by Goldberg & Barres
Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein p439
Tadzia GrandPré, Fumio Nakamura, Timothy Vartanian and Stephen M. Strittmatter
doi:10.1038/35000226
First paragraph | Full Text | PDF (2,602K)
Torque-generating units of the flagellar motor of Escherichia coli have a high duty ratio p444
William S. Ryu, Richard M. Berry and Howard C. Berg
doi:10.1038/35000233
First paragraph | Full Text | PDF (2,374K)
The DExH protein NPH-II is a processive and directional motor for unwinding RNA p447
Eckhard Jankowsky, Christian H. Gross, Stewart Shuman and Anna Marie Pyle
doi:10.1038/35000239
First paragraph | Full Text | PDF (557K)
DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination p451
Clifford D. Mol, Tadahide Izumi, Sankar Mitra and John A. Tainer
doi:10.1038/35000249
First paragraph | Full Text | PDF (1,529K) | Supplementary information
Design of single-layer 
-sheets without a hydrophobic core p456
Shohei Koide, Xiaolin Huang, Karl Link, Akiko Koide, Zimei Bu and Donald M. Engelman
doi:10.1038/35000255
First paragraph | Full Text | PDF (2,003K)
New on the Market
Going out on a LIMS p461
A round-up of lab information management systems and automation.
doi:10.1038/35000293
Careers and Recruitment
Bioengineering programmes rise to meet the challenge of a young science p463
When biology met engineering, they created a new field for scientists who don't want to be hedged into one discipline.
Brendan Horton
doi:10.1038/35000341
Passing the baton? p463
Brendan Horton
Exploring the territory in tissue engineering p464
Potter Wickware
doi:10.1038/35000344
Creative fusion of many minds p464
Brendan Horton
doi:10.1038/35000412
Progress from a fragile start p466
Potter Wickware
doi:10.1038/35000347
Insiders advise on first steps to a career p466
Potter Wickware
doi:10.1038/35000350
