Opinion

Private vs public genomics? p117

Commercial sequencing of genomes has stimulated scientific progress. But the increasing value of such companies risks exacerbating the conflict between the interests of investors and of the public. Both need to worry.

doi:10.1038/35003001

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Millennium bugs p117

AIDS in Africa threatens the United States. It should act accordingly.

doi:10.1038/35003003

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News

Celera turns to public genome data to speed up endgame... p119

Paul Smaglik and Declan Butler

doi:10.1038/35003269

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...as Internet fervour hits genomics p119

David Dickson

doi:10.1038/35003271

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Inadequate optics 'threat to US laser facility' p120

Colin Macilwain

doi:10.1038/35003273

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UK discussed ban on foreign job ads in 1960s p121

Natasha Loder

doi:10.1038/35003005

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Bell Labs win superconductivity patent p121

Colin Macilwain

doi:10.1038/35003008

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Genetics takes off in Naples as institute moves south p122

Alison Abbott

doi:10.1038/35003011

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NIH seeks funding for neuroscience centre ... p123

Paul Smaglik

doi:10.1038/35003014

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... as lobbyists anticipate more money for all p123

Colin Macilwain and Paul Smaglik

doi:10.1038/35003017

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Greenwich 'could be symbolic timekeeper for electronic era' p124

Natasha Loder

doi:10.1038/35003019

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Brussels research chief backs European website proposal p124

Declan Butler

doi:10.1038/35003021

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Japanese support biotech start-ups p124

Robert Triendl

doi:10.1038/35003024

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News Analysis

Biologists flock to 'evo-devo' in a quest to read the recipes of life p125

How has the diversity of animal and plant forms evolved? Researchers are combining evolution, development and genetics to address this hot topic.

Rex Dalton

doi:10.1038/35003026

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news in brief p126

doi:10.1038/35003029

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Correspondence

Global bodies won't save the environment: it needs grass-roots efforts ... p129

Ignacio H. Chapela

doi:10.1038/35003032

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... or should private enterprise take over? p129

Matthew Brown and Donald R. Leal

doi:10.1038/35003034

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Proteins and the naked truth about e-commerce p129

Dattatray Parasnis

doi:10.1038/35003036

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Proteins and the naked truth about e-commerce p130

Alex May

doi:10.1038/35003038

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EPA error risked halving India's rice harvest p130

E. S. R. Gopal

doi:10.1038/35003040

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Wherever HIV originated, polio vaccine is safe now p130

Ka-Wing Wong

doi:10.1038/35003042

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East German academics faced unfair hurdles p130

Bernd Legler and Guy Moore

doi:10.1038/35003044

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Commentary

Sowing nuclear misconceptions p131

In its recent deliberations over the Comprehensive Test Ban Treaty, the US Senate was not well served by the directors of the US weapons laboratories.

doi:10.1038/35003046

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Book Reviews

The truth is in here p135

How a science-fiction TV series treads the line of scientific plausibility.

Henry Gee reviews The Real Science Behind The X-Files: Microbes, Meteorites and Mutants by Anne Simon

doi:10.1038/35003050

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Simplicity out of complexity p136

Jonathan R. Ellis reviews Strange Beauty: Murray Gell-Mann and the Revolution in Twentieth-Century Physics by George Johnson

doi:10.1038/35003053

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Of pigs, poultry and permafrost p137

David A. J. Tyrrell reviews Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus that Caused It by Gina Kolata

doi:10.1038/35003056

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Integrals of disease p138

Graham F. Medley reviews Statistical Aspects of BSE and vCJD: Models for Epidemics by Christl A. Donnelly and Neil M. Ferguson

doi:10.1038/35003060

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Science in culture p138

Alison Abbott reviews The life of Paul Dirac, The Oracle of Delphi

doi:10.1038/35003062

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Millennium Essay

Positioning the goalposts p139

The best environmental policy depends on how you frame the question.

John Maddox

doi:10.1038/35003065

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Futures

Deep Ice and DNA languages p141

Life, but not intelligence, abounds under the ice of frozen planets.

Greg Bear

doi:10.1038/35003068

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News and Views

Molecular computation: DNA computing on a chip p143

In a DNA computer, the input and output are both strands of DNA. A computer in which the strands are attached to the surface of a chip can now solve difficult problems quite quickly.

Mitsunori Ogihara and Animesh Ray

doi:10.1038/35003071

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Aerodynamics: From insects to microvehicles p144

Robin Wootton

doi:10.1038/35003074

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Astronomy: Eyes wide shut p145

David Jewitt

doi:10.1038/35003077

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100 and 50 years ago p145

doi:10.1038/35003080

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Plant development: Gateway to the chloroplast p148

Kenneth Cline

doi:10.1038/35003082

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Telomeres: A tale of ends p149

Victoria Lundblad

doi:10.1038/35003085

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Phase transitions: Jumping between liquid states p151

Paul McMillan

doi:10.1038/35003088

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Nuclear polarization: More spins for protons p151

Sarah Tomlin

doi:10.1038/35003090

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Palaeontology: Fossil fish up for election p152

Meemann Chang

doi:10.1038/35003093

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Neurobiology: Internal model visualized p153

Masao Ito

doi:10.1038/35003097

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Daedalus: Coal, air, fire and water p154

David Jones

doi:10.1038/35003101

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Brief Communications

A pygostyle from a non-avian theropod p155

The independent evolution of a bird-like tail has been discovered in an oviraptorosaur.

Rinchen Barsbold, Philip J. Currie, Nathan P. Myhrvold, Halszka Osmólska, Khishigjaw Tsogtbaatar and Mahito Watabe

doi:10.1038/35003103

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Evolutionary fitness: Tall men have more reproductive success p156

B. Pawlowski, R. I. M. Dunbar and A. Lipowicz

doi:10.1038/35003107

First paragraph | Full Text | PDF (108K)

Physiology: Eel fat stores are enough to reach the Sargasso p156

Vincent J. T. van Ginneken and Guido E. E. J. M. van den Thillart

doi:10.1038/35003110

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Orthography: Children learn an untaught rule of spelling p157

Peter Bryant, Terezinha Nunes and Rowena Snaith

doi:10.1038/35003114

First paragraph | Full Text | PDF (144K) | Supplementary information

Environmental genetics: Rapid chromosomal evolution in island mice p158

Janice Britton-Davidian, Josette Catalan, Maria da Graça Ramalhinho, Guila Ganem, Jean-Christophe Auffray, Ruben Capela, Manuel Biscoito, Jeremy B. Searle and Maria da Luz Mathias

doi:10.1038/35003116

First paragraph | Full Text | PDF (115K)

Article

MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans p159

Shawn Ahmed and Jonathan Hodgkin

doi:10.1038/35003120

Abstract | Full Text | PDF (280K)

See also: News and Views by Lundblad

Letters to Nature

A reduced estimate of the number of kilometre-sized near-Earth asteroids p165

David Rabinowitz, Eleanor Helin, Kenneth Lawrence and Steven Pravdo

doi:10.1038/35003128

First paragraph | Full Text | PDF (92K)

See also: News and Views by Jewitt

Measurement of the spatial coherence of a trapped Bose gas at the phase transition p166

I. Bloch, T. W. Hänsch and T. Esslinger

doi:10.1038/35003132

First paragraph | Full Text | PDF (264K)

A first-order liquid–liquid phase transition in phosphorus p170

Yoshinori Katayama, Takeshi Mizutani, Wataru Utsumi, Osamu Shimomura, Masaaki Yamakata and Ken-ichi Funakoshi

doi:10.1038/35003143

First paragraph | Full Text | PDF (373K)

See also: News and Views by

Nanoscopic channel lattices with controlled anisotropic wetting p173

M. Gleiche, L. F. Chi and H. Fuchs

doi:10.1038/35003149

First paragraph | Full Text | PDF (210K)

DNA computing on surfaces p175

Qinghua Liu, Liman Wang, Anthony G. Frutos, Anne E. Condon, Robert M. Corn and Lloyd M. Smith

doi:10.1038/35003155

First paragraph | Full Text | PDF (254K)

See also: News and Views by Ogihara & Ray

Evidence for enhanced mixing over rough topography in the abyssal ocean p179

J. R. Ledwell, E. T. Montgomery, K. L. Polzin, L. C. St. Laurent, R. W. Schmitt and J. M. Toole

doi:10.1038/35003164

First paragraph | Full Text | PDF (320K)

Osmotic generation of 'anomalous' fluid pressures in geological environments p182

C. E. Neuzil

doi:10.1038/35003174

First paragraph | Full Text | PDF (171K) | Supplementary information

The most primitive osteichthyan braincase? p185

Alison M. Basden, Gavin C. Young, Michael I. Coates and Alex Ritchie

doi:10.1038/35003183

First paragraph | Full Text | PDF (403K)

See also: News and Views by Chang

Molecular evidence regarding the origin of echolocation and flight in bats p188

Emma C. Teeling, Mark Scally, Diana J. Kao, Michael L. Romagnoli, Mark S. Springer and Michael J. Stanhope

doi:10.1038/35003188

First paragraph | Full Text | PDF (171K)

Human cerebellar activity reflecting an acquired internal model of a new tool p192

Hiroshi Imamizu, Satoru Miyauchi, Tomoe Tamada, Yuka Sasaki, Ryousuke Takino, Benno Pütz, Toshinori Yoshioka and Mitsuo Kawato

doi:10.1038/35003194

First paragraph | Full Text | PDF (301K) | Supplementary information

See also: News and Views by Ito

A constitutively open potassium channel formed by KCNQ1 and KCNE3 p196

Björn C. Schroeder, Siegfried Waldegger, Susanne Fehr, Markus Bleich, Richard Warth, Rainer Greger and Thomas J. Jentsch

doi:10.1038/35003200

First paragraph | Full Text | PDF (300K) | Supplementary information

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages p199

Célio G. Freire-de-Lima, Danielle O. Nascimento, Milena B. P. Soares, Patricia T. Bozza, Hugo C. Castro-Faria-Neto, Fernando G. de Mello, George A. DosReis and Marcela F. Lopes

doi:10.1038/35003208

First paragraph | Full Text | PDF (174K)

The major protein import receptor of plastids is essential for chloroplast biogenesis p203

Jörg Bauer, Kunhua Chen, Andreas Hiltbunner, Ernst Wehrli, Monika Eugster, Danny Schnell and Felix Kessler

doi:10.1038/35003214

First paragraph | Full Text | PDF (447K)

See also: News and Views by Cline

Interferon- elicits arteriosclerosis in the absence of leukocytes p207

George Tellides, Denis A. Tereb, Nancy C. Kirkiles-Smith, Richard W. Kim, Jean H. Wilson, Jeffrey S. Schechner, Marc I. Lorber and Jordan S. Pober

doi:10.1038/35003221

First paragraph | Full Text | PDF (395K)

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b p211

Kurt Bachmaier, Connie Krawczyk, Ivona Kozieradzki, Young-Yun Kong, Takehiko Sasaki, Antonio Oliveira-dos-Santos, Sanjeev Mariathasan, Dennis Bouchard, Andrew Wakeham, Annick Itie, Jenny Le, Pamela S. Ohashi, Ildiko Sarosi, Hiroshi Nishina, Stan Lipkowitz and Josef M. Penninger

doi:10.1038/35003228

First paragraph | Full Text | PDF (319K) | Supplementary information

Cbl-b regulates the CD28 dependence of T-cell activation p216

Yungping J. Chiang, Hemanta K. Kole, Karen Brown, Mayumi Naramura, Shigetomo Fukuhara, Ren-Ju Hu, Ihn Kyung Jang, J. Silvio Gutkind, Ethan Shevach and Hua Gu

doi:10.1038/35003235

First paragraph | Full Text | PDF (232K) | Supplementary information

Measurement of thermal contribution to photoreceptor sensitivity p220

Ari Koskelainen, Petri Ala-Laurila, Nanna Fyhrquist and Kristian Donner

doi:10.1038/35003242

First paragraph | Full Text | PDF (175K)

Bioorganic synthesis of lipid-modified proteins for the study of signal transduction p223

Benjamin Bader, Karsten Kuhn, David J. Owen, Herbert Waldmann, Alfred Wittinghofer and Jürgen Kuhlmann

doi:10.1038/35003249

First paragraph | Full Text | PDF (214K)

New on the Market

Quick-fire genes, pipettes, RNA p227

"It was a dark and stormy night..." Nalgene have just the thing for that first line.

doi:10.1038/35003254

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