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Nature 402, 471-472 (2 December 1999) | doi:10.1038/44973
Open Innovation Challenges
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Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
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Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
nature jobs
Associate Professor or Full Professor
- South Dakota State University
- Brookings, SD
Chemical Reaction Engineering & Reactor Design
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
Alzheimer's disease: A firm base for drug development
Bart De Strooper & Gerhard König
Alzheimer's disease is a progressive dementia in which massive deposits of aggregated protein-breakdown products — amyloid plaques and neurofibrillary tangles — accumulate in the brain. The amyloid plaques are thought to be responsible for the devastating mental decline in patients with Alzheimer's disease, and the main component of these plaques is a small peptide called amyloid
(A
).
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