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Nature 402, 447-448 (2 December 1999) | doi:10.1038/44892

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'Finishing' success marks major genome sequencing milestone ...

Declan Butler

Genome scientists in Britain and elsewhere have shown that they can surmount the enormous difficulties of closing the gaps between ordered chunks of sequence in the human genome — the 'finishing' step.The evidence comes with the complete sequence of chromosome 22, published in this issue (see pages 467 and 489), and confirms the achievement as a milestone for the publicly funded international human genome consortium.