Table of contents
Volume 402 Number 6759 pp217-328
Opinion
Coming to terms with the human factor p217
The official report into the loss of the Mars Climate Orbiter raises many issues that need to be coolly scrutinized. High on the list are NASA's efforts to increase its cost-effectiveness by launching 'better, faster, cheaper' missions.
doi:10.1038/46107
Keeping the record straight on AIDS p217
Recent statements by South Africa's president on the hazards of AZT need a sympathetic but firm response.
doi:10.1038/46109
News
Alliance of US labs plans to build map of cell signalling pathways p219
Alison Abbott
doi:10.1038/46111
Scientists reel after Indian cyclone p219
K.S. Jayaraman
doi:10.1038/46115
Japan calls for partnership to develop semiconductors p220
Asako Saegusa
doi:10.1038/46117
France could face 'scientific recession', warns council p221
Heather McCabe
doi:10.1038/46120
Concern over Mars Lander as inquiry reports on Orbiter loss p221
Tony Reichhardt
doi:10.1038/46122
Professors use web to catch students who plagiarize... p222
Rex Dalton
doi:10.1038/46125
... and author gets similar paper retracted p222
Rex Dalton
doi:10.1038/46128
Privatization of UK weapons labs under fire p223
Natasha Loder
doi:10.1038/46130
Jobs boost for Spanish science p223
Xavier Bosch
doi:10.1038/46133
Opposition pledges to raise New Zealand science budget p224
Peter Pockley
doi:10.1038/46135
Body takes centre stage in UK's Millennium Dome p224
Natasha Loder
doi:10.1038/46137
AZT critics 'swayed South African president' p225
Mike Cherry
doi:10.1038/46140
Russian peace researcher detained p225
Carl Levitin
doi:10.1038/46143
Correspondence
Genetically modified foods face rigorous safety evaluation p229
M. J. Gasson
doi:10.1038/46147
Bureaucracy blights Japan's safety record p229
Kazuo Inoue
doi:10.1038/46149
Challenge for global e-journal project p230
Lance Sultzbaugh
doi:10.1038/46151
How the Church moves with the times p230
Guy Consolmagno
doi:10.1038/46153
Unfair exchange p230
David Colquhoun
doi:10.1038/46155
Commentary
Much food, many problems p231
A new agriculture, combining genetic modification technology with sustainable farming, is our best hope for the future.
doi:10.1038/46157
Book Reviews
Creating a climate for change p233
Rumours of the demise of the Kyoto Protocol are premature.
Nancy Kete reviews The Kyoto Protocol — A Guide and Assessment by Michael Grubb, Christiaan Vrolijk and Duncan Brack
doi:10.1038/46159
Haunting images from the edge of extinction p233
doi:10.1038/46161
Let them think cake p234
Marian Stamp Dawkins reviews Design for a Life: How Behaviour Develops by Patrick Bateson and Paul Martin
doi:10.1038/46163
Cajal's scientific prescience revisited p235
Harvey J. Karten reviews Texture of the Nervous System of Man and the Vertebrates: Volume I by Santiago Ramón y Cajal
doi:10.1038/46165
Science in culture p236
Martin Kemp reviews Welsh waters Paintings by Ian Welsh
doi:10.1038/46169
Millennium Essay
Achilles and the maggots p237
... or how the Iliad inspired a renaissance scholar to show how flies are made.
Paolo Mazzarello
doi:10.1038/46172
Futures
When thought-mail fails p239
From the twenty-second-century diary of one who yearns to be a nobody.
Ian Watson
doi:10.1038/46176
News and Views
Biophysics: Fishing for function in noise p241
Stochastic resonance increases the ability of some nonlinear systems to detect weak signals. Paddlefish are now shown to use stochastic resonance to locate and capture prey, implicating this phenomenon in animal behaviour.
James J. Collins
doi:10.1038/46179
Materials science: Open season for solid frameworks p242
Michael J. Zaworotko
doi:10.1038/46182
Ageing: Mutant mice live longer p243
Leonard Guarente
doi:10.1038/46185
Geochemistry: Molten rocks in motion p245
Michael R. Perfit
doi:10.1038/46189
Molecular motors: What makes ATP synthase spin? p247
Paul D. Boyer
doi:10.1038/46193
100 and 50 years ago p247
doi:10.1038/46197
Daedalus: Frankenstein lives! p249
David Jones
doi:10.1038/46199
erratum: Carbon cycle: The blast in the past p249
doi:10.1038/99999
Obituary: Guido Pontecorvo (1907–99) p250
Obaid Siddiqi
doi:10.1038/46201
Brief Communications
Why 'false' colours are seen by butterflies p251
A combination of colour and polarized reflections helps them to choose oviposition sites.
Almut Kelber
doi:10.1038/46204
First paragraph | Full Text | PDF (100K)
Magnetic properties: Ferromagnetism in the hexaborides p251
M. E. Zhitomirsky, T. M. Rice and V. I. Anisimov
doi:10.1038/46207
First paragraph | Full Text | PDF (141K)
Developmental biology: Variable cell number in nematodes p253
Ana Cunha, Ricardo B. R. Azevedo, Scott W. Emmons and Armand M. Leroi
doi:10.1038/46211
First paragraph | Full Text | PDF (155K)
Nanoelectronics: Growing Y-junction carbon nanotubes p253
Jing Li, Chris Papadopoulos and Jimmy Xu
doi:10.1038/46214
First paragraph | Full Text | PDF (156K)
Review
Selecting and maintaining a diverse T-cell repertoire p255
Ananda W. Goldrath and Michael J. Bevan
doi:10.1038/46218
Abstract | Full Text | PDF (254K)
Article
Structural changes linked to proton translocation by subunit c of the ATP synthase p263
Vinit K. Rastogi and Mark E. Girvin
doi:10.1038/46224
Abstract | Full Text | PDF (3,185K)
Letters to Nature
A low-temperature origin for the planetesimals that formed Jupiter p269
Tobias Owen, Paul Mahaffy, H. B. Niemann, Sushil Atreya, Thomas Donahue, Akiva Bar-Nun and Imke de Pater
doi:10.1038/46232
First paragraph | Full Text | PDF (91K)
Lithium nucleosynthesis in the Sun inferred from the solar-wind 7Li/6Li ratio p270
Marc Chaussidon and François Robert
doi:10.1038/46235
First paragraph | Full Text | PDF (300K)
Carbon nanotube intramolecular junctions p273
Zhen Yao, Henk W. Ch. Postma, Leon Balents and Cees Dekker
doi:10.1038/46241
First paragraph | Full Text | PDF (804K) | Supplementary information
Design and synthesis of an exceptionally stable and highly porous metal-organic framework p276
Hailian Li, Mohamed Eddaoudi, M. O'Keeffe and O. M. Yaghi
doi:10.1038/46248
First paragraph | Full Text | PDF (241K) | Supplementary information
Abrupt termination of the 1997–98 El Niño in response to a Madden–Julian oscillation p279
Yukari N. Takayabu, Toshio Iguchi, Misako Kachi, Akira Shibata and Hiroshi Kanzawa
doi:10.1038/46254
First paragraph | Full Text | PDF (576K)
Combined dynamic and geochemical evidence for convergent melt flow beneath the East Pacific Rise p282
Marc Spiegelman and Jennifer R. Reynolds
doi:10.1038/46260
First paragraph | Full Text | PDF (304K)
Energetic constraints on the diet of terrestrial carnivores p286
Chris Carbone, Georgina M. Mace, S. Craig Roberts and David W. Macdonald
doi:10.1038/46266
First paragraph | Full Text | PDF (193K)
Total lipid energy as a proxy for total egg production by fish stocks p288
C. Tara Marshall, Nathalia A. Yaragina, Yvan Lambert and Olav S. Kjesbu
doi:10.1038/46272
First paragraph | Full Text | PDF (135K)
Use of behavioural stochastic resonance by paddle fish for feeding p291
David F. Russell, Lon A. Wilkens and Frank Moss
doi:10.1038/46279
First paragraph | Full Text | PDF (342K)
The amygdala modulates prefrontal cortex activity relative to conditioned fear p294
René Garcia, Rose-Marie Vouimba, Michel Baudry and Richard F. Thompson
doi:10.1038/46286
First paragraph | Full Text | PDF (227K)
Kainate receptors are involved in synaptic plasticity p297
Zuner A. Bortolotto, Vernon R. J. Clarke, Caroline M. Delany, Michael C. Parry, Ilse Smolders, Michel Vignes, Ken H. Ho, Peter Miu, Bradford T. Brinton, Robert Fantaske, Ann Ogden, Mary Gates, Paul L. Ornstein, David Lodge, David Bleakman and Graham L. Collingridge
doi:10.1038/46290
First paragraph | Full Text | PDF (549K)
Activation of the epithelial Na+ channel (ENaC) requires CFTR Cl- channel function p301
M. M. Reddy, M. J. Light and P. M. Quinton
doi:10.1038/46297
First paragraph | Full Text | PDF (173K)
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand p304
Young-Yun Kong, Ulrich Feige, Iidiko Sarosi, Brad Bolon, Anna Tafuri, Sean Morony, Casey Capparelli, Ji Li, Robin Elliott, Susan McCabe, Thomas Wong, Giuseppe Campagnuolo, Erika Moran, Earl R. Bogoch, Gwyneth Van, Linh T. Nguyen, Pamela S. Ohashi, David L. Lacey, Eleanor Fish, William J. Boyle and Josef M. Penninger
doi:10.1038/46303
First paragraph | Full Text | PDF (551K) | Supplementary information
The p66shc adaptor protein controls oxidative stress response and life span in mammals p309
Enrica Migliaccio, Marco Giorgio, Simonetta Mele, Giuliana Pelicci, Paolo Reboldi, Pier Paolo Pandolfi, Luisa Lanfrancone and Pier Giuseppe Pelicci
doi:10.1038/46311
First paragraph | Full Text | PDF (326K) | Supplementary information
Structural insights into phosphoinositide 3-kinase catalysis and signalling p313
Edward H. Walker, Olga Perisic, Christian Ried, Len Stephens and Roger L. Williams
doi:10.1038/46319
First paragraph | Full Text | PDF (3,384K)
Sustained oscillations in living cells p320
Sune Danø, Preben Graae Sørensen and Finn Hynne
doi:10.1038/46329
First paragraph | Full Text | PDF (335K)
A ribozyme that lacks cytidine p323
Jeff Rogers and Gerald F. Joyce
doi:10.1038/46335
First paragraph | Full Text | PDF (142K)
New on the Market
Out of sequence p327
New ways of extracting, sequencing, measuring and binding with DNA.
doi:10.1038/46340
