Table of contents
Volume 402 Number 6758 pp107-215
Opinion
The increasing opacity of gene therapy p107
The influence of commercial interests is highlighted by recent reports of deaths during trials of gene therapies. The loosening of public scrutiny of such studies needs to be reconsidered.
doi:10.1038/45865
A cold wind from the East p107
Charges faced by a Ukrainian scientist could have a chilling effect on the future of international collaboration.
doi:10.1038/45867
News
US universities find that demand for botanists exceeds supply p109
Rex Dalton
doi:10.1038/45869
Australia 'tops per capita emissions' p109
Peter Pockley
doi:10.1038/45873
Publishing group offers peer review on PubMed Central p110
Declan Butler
doi:10.1038/45875
Ukraine denies arresting biologist p110
Natasha Loder
doi:10.1038/45877
Daresbury senses victory in battle for UK synchrotron p111
Natasha Loder and Heather McCabe
doi:10.1038/45879
Cambridge, UK, hopes MIT magic will work on joint institute p111
Colin Macilwain
doi:10.1038/45882
Race is on to find successor to Varmus at NIH p112
Meredith Wadman
doi:10.1038/45884
Surprise boost for stem-cell work p112
Colin Macilwain
doi:10.1038/45888
University debate boils over in Australia p113
Peter Pockley
doi:10.1038/45890
German scientists must repay fees p113
Quirin Schiermeier
doi:10.1038/45893
Israel shuts four 'incubators' for high-tech companies p114
Haim Watzman
doi:10.1038/45896
$2m ransom sought for kidnapped ecologists p114
Carl Levitin
doi:10.1038/45898
News Analysis
Publishers map out a way forward in response to free online archives p115
Commercial publishers plan to link up their journals, stealing the thunder of free repositories for life-science papers — and protecting their revenues.
Declan Butler
doi:10.1038/45901
Correspondence
Survey confirms fears about licensing of genetic tests p118
Anna Schissel, Jon F. Merz and Mildred K. Cho
doi:10.1038/45907
Parents need catch-up courses to boost careers p118
Wendy Powell
doi:10.1038/45910
Lacking cover p118
Vani Kalyanaraman
doi:10.1038/45912
Book Reviews
Lessons in molecular gymnastics p119
Viewing the future of nanotechnology through rose-tinted spectacles.
Philip Ball reviews Travels to the Nanoworld: Miniature Machinery in Nature and Technology by Michael Gross
doi:10.1038/45914
Evolutionary play on maternal behaviour p120
Kristen Hawkes reviews Mother Nature: A History of Mothers, Infants and Natural Selection by Sarah Blaffer Hrdy
doi:10.1038/45917
Nurturing the nature of art p120
doi:10.1038/45919
Rocks of the ages p121
Robert W. Buddemeier reviews Reef Evolution by Rachel Wood
doi:10.1038/45922
Growing old in Germany p122
John Grimley Evans reviews The Berlin Aging Study: Aging from 70 to 100
doi:10.1038/45924
Holding a mirror up to da Vinci's science p122
doi:10.1038/45926
Millennium Essay
Dark on a light subject p123
Nineteenth-century physicists couldn't agree about the speed of light.
Brian Pippard
doi:10.1038/45929
Futures
Homo sapiens declared extinct p125
Yes, human beings have finally gone, but the 24-hour global party continues.
Bruce Sterling
doi:10.1038/45932
News and Views
Survival of the weakest p127
Many asteroids have a porous structure, which helps them absorb energy from collisions without being smashed to bits. This shows how planets might have formed, but could be bad news should an asteroid ever threaten Earth.
Erik Asphaug
doi:10.1038/45935
RNA interference: Policing rogue genes p128
Rueyling Lin and Leon Avery
doi:10.1038/45938
100 and 50 years ago p131
doi:10.1038/45941
Genetics: Distorting sex ratios p131
Keith R. Willison
doi:10.1038/45943
Condensed matter: Through a glass, lightly p132
A. Lindsay Greer
doi:10.1038/45946
Cell cycle: Dual control of mitotic exit p133
Susanne Prinz and Angelika Amon
doi:10.1038/45949
Plant genetics: Knocking out nodules p135
Herman P. Spaink
doi:10.1038/45952
Daedalus: Asteroidal defence p136
David Jones
doi:10.1038/45955
Brief Communications
Motherhood improves learning and memory p137
Neural activity in rats is enhanced by pregnancy and the demands of rearing offspring.
Craig H. Kinsley, Lisa Madonia, Gordon W. Gifford, Kara Tureski, Garrett R. Griffin, Catherine Lowry, Jamison Williams, Jennifer Collins, Heather McLearie and Kelly G. Lambert
doi:10.1038/45957
Laser optics: Fractal modes in unstable resonators p138
G. P. Karman, G. S. McDonald, G. H. C. New and J. P. Woerdman
doi:10.1038/45960
First paragraph | Full Text | PDF (50K)
Biodiversity: Seed germination in rainforest fragments p139
Emilio M. Bruna
doi:10.1038/45963
First paragraph | Full Text | PDF (65K)
Vision: Dichromatism in macaque monkeys p139
Akishi Onishi, Satoshi Koike, Miki Ida, Hiroo Imai, Yoshinori Shichida, Osamu Takenaka, Akitoshi Hanazawa, Hidehiko Konatsu, Akichika Mikami, Shunji Goto, Bambang Suryobrotoq, Kenji Kitahara and Tetsuo Yamamori
doi:10.1038/45966
First paragraph | Full Text | PDF (65K)
Articles
A protein kinase encoded by the t complex responder gene causes non-mendelian inheritance p141
Bernhard G. Herrmann, Birgit Koschorz, Karin Wertz, K. John McLaughlin and Andreas Kispert
doi:10.1038/45970
Abstract | Full Text | PDF (323K)
Identification of in vivo substrates of the chaperonin GroEL p147
Walid A. Houry, Dmitrij Frishman, Christoph Eckerskorn, Friedrich Lottspeich and F. Ulrich Hartl
doi:10.1038/45977
Abstract | Full Text | PDF (387K)
Letters to Nature
Compaction as the origin of the unusual craters on the asteroid Mathilde p155
Kevin R. Housen, Keith A. Holsapple and Michael E. Voss
doi:10.1038/45985
First paragraph | Full Text | PDF (175K)
Spatial sampling of crystal electrons by in-flight annihilation of fast positrons p157
A. W. Hunt, D. B. Cassidy, F. A. Selim, R. Haakenaasen, T. E. Cowan, R. H. Howell, K. G. Lynn and J. A. Golovchenko
doi:10.1038/45990
First paragraph | Full Text | PDF (133K)
Diffusion mechanisms in metallic supercooled liquids and glasses p160
X.-P. Tang, Ulrich Geyer, Ralf Busch, William L. Johnson and Yue Wu
doi:10.1038/45996
First paragraph | Full Text | PDF (159K)
Diamond formation by thermal activation of graphite p162
A. V. Palnichenko, A. M. Jonas, J.-C. Charlier, A. S. Aronin and J.-P. Issi
doi:10.1038/46000
First paragraph | Full Text | PDF (320K)
Modulation of cadmium uptake in phytoplankton by seawater CO2 concentration p165
Jay T. Cullen, Todd W. Lane, François M. M. Morel and Robert M. Sherrell
doi:10.1038/46007
First paragraph | Full Text | PDF (123K)
Influence of NOx emissions from ships on tropospheric photochemistry and climate p167
Mark G. Lawrence and Paul J. Crutzen
doi:10.1038/46013
First paragraph | Full Text | PDF (964K)
A polar vortex in the Earth's core p170
Peter Olson and Jonathan Aurnou
doi:10.1038/46017
First paragraph | Full Text | PDF (246K)
The insidious effect of diatoms on copepod reproduction p173
A. Miralto, G. Barone, G. Romano, S. A. Poulet, A. Ianora, G. L. Russo, I. Buttino, G. Mazzarella, M. Laabir, M. Cabrini and M. G. Giacobbe
doi:10.1038/46023
First paragraph | Full Text | PDF (215K) | Supplementary information
Signal but not noise changes with perceptual learning p176
J. Gold, P. J. Bennett and A. B. Sekuler
doi:10.1038/46027
First paragraph | Full Text | PDF (191K)
Conflict monitoring versus selection-for-action in anterior cingulate cortex p179
Matthew Botvinick, Leigh E. Nystrom, Kate Fissell, Cameron S. Carter and Jonathan D. Cohen
doi:10.1038/46035
First paragraph | Full Text | PDF (154K)
Two functionally distinct 
2-adrenergic receptors regulate sympathetic neurotransmission p181
Lutz Hein, John D. Altman and Brian K. Kobilka
doi:10.1038/46040
First paragraph | Full Text | PDF (196K)
Rapid gating and anion permeability of an intracellular aquaporin p184
Masato Yasui, Akihiro Hazama, Tae-Hwan Kwon, Søren Nielsen, Wm. B. Guggino and Peter Agre
doi:10.1038/46045
First paragraph | Full Text | PDF (801K)
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene p187
Guo-Liang Xu, Timothy H. Bestor, Déborah Bourc'his, Chih-Lin Hsieh, Niels Tommerup, Merete Bugge, Maj Hulten, Xiaoyan Qu, James J. Russo and Evani Viegas-Péquignot
doi:10.1038/46052
First paragraph | Full Text | PDF (253K)
A plant regulator controlling development of symbiotic root nodules p191
Leif Schauser, Andreas Roussis, Jiri Stiller and Jens Stougaard
doi:10.1038/46058
First paragraph | Full Text | PDF (454K)
CaMKII regulates the density of central glutamatergic synapses in vivo p195
Christopher Rongo and Joshua M. Kaplan
doi:10.1038/46065
First paragraph | Full Text | PDF (282K)
Diverse behavioural defects caused by mutations in Caenorhabditis elegans unc-43 CaM Kinase II p199
David J. Reiner, Elizabeth M. Newton, Hong Tian and James H. Thomas
doi:10.1038/46072
First paragraph | Full Text | PDF (207K)
APCCdc20 promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5 p203
Masaki Shirayama, Attila Tóth, Marta Gálová and Kim Nasmyth
doi:10.1038/46080
First paragraph | Full Text | PDF (973K)
The RNA splicing factor hSlu7 is required for correct 3' splice-site choice p207
Katrin Chua and Robin Reed
doi:10.1038/46086
First paragraph | Full Text | PDF (205K)
New on the Market
Looking for a reaction p211
Monoclonal and polyclonal antibodies, immunoassays, immunoetcetera.
doi:10.1038/46092
Careers and Recruitment
From bench to bedside... research makes the translational transition p213
How is biological research being translated into clinical practice? The challenges of information management need to be applied urgently.
Brendan Horton
doi:10.1038/46097
Improving the plight of the physician–scientist in the US p215
Diane Gershon
doi:10.1038/46100
Clinical research in practice p215
Diane Gershon
doi:10.1038/46104
