Table of contents


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Opinion

Financial flexibility the key to Germany's scientific prosperity p623

Ten years after the fall of the Berlin Wall, and despite a traumatic transition, science in east Germany is flourishing. Nationwide obstacles to progress require increased federal leverage for their removal.

doi:10.1038/44196


Caution: traditional knowledge p623

Principles of merit need to be spelt out in distinguishing valuable knowledge from myth.

doi:10.1038/44198


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News

Medicine Nobel goes to pioneer of protein guidance mechanisms p625

Marie-Thérèse Heemels

doi:10.1038/44200


Dutch theoreticians win physics prize p626

Karl Ziemelis

doi:10.1038/44203


Split-second chemistry is rewarded p626

Philip Ball

doi:10.1038/44206


Publishers agree on a 'seamless web' p626

David Dickson

doi:10.1038/44209


US State Department hires consultant to boost role of science p627

Colin Macilwain

doi:10.1038/44211


Varmus announces decision to quit NIH for cancer centre p627

Colin Macilwain

doi:10.1038/44213


Japan plans to join array project p627

Asako Saegusa and Natasha Loder

doi:10.1038/44215


Aim for better business sense to bolster Russian science p628

Carl Levitin

doi:10.1038/44218


Anger at Israeli sex crimes DNA bank p628

Haim Watzman

doi:10.1038/44221


'Faked' rock-dating data charge dismissed... p629

Rex Dalton

doi:10.1038/44223


... and German garlic study under scrutiny p629

Quirin Schiermeier

doi:10.1038/44225


Berkeley puts $500m into multidisciplinary approach to disease p630

Rex Dalton

doi:10.1038/44228


Joint institute set to boost Austria's genome research p630

Quirin Schiermeier

doi:10.1038/44230


Institut Pasteur names Kourilsky as new director p630

Heather McCabe

doi:10.1038/44232


ICSU seeks to classify 'traditional knowledge' p631

David Dickson

doi:10.1038/44235


UK government not convinced by claims for flu drug p631

Natasha Loder

doi:10.1038/44238


News in brief p632

doi:10.1038/44240


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Correspondence

Correction p633

doi:10.1038/44240


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Briefings

Tough measures bring a scarred science back to the world stage p635

Ten years after the fall of the Berlin Wall, east German scientists are putting the pain of reunification behind them, as Alison Abbott reports.

doi:10.1038/44244


Max Planck Society's careful planning reaps benefits p637

doi:10.1038/44251


Rush rescue programme has achieved mixed results p638

doi:10.1038/44255


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Correspondence

Conventional crops are the test of GM prejudice p640

Anthony Trewavas and C. J. Leaver

doi:10.1038/44258


Substantial equivalence is a useful tool p640

Peter Kearns and Paul Mayers

doi:10.1038/44260


No GM conspiracy p640

Derek Burke

doi:10.1038/44262


Putting transparency into ethical balance p641

Dai Rees

doi:10.1038/44264


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Commentary

Do-it-yourself climate prediction p642

Anyone with a home PC could join climate modellers in their attempt to forecast how the Earth's climate will evolve in the next century.

doi:10.1038/44266


Top

Book Reviews

Save Mozart for later p643

Neurobiology offers no evidence that infancy is a privileged time for learning.

Elizabeth Spelke reviews The Myth of the First Three Years: A New Understanding of Early Brain Development and Lifelong Learning by John T. Bruer

doi:10.1038/44268


Oiling the wheels of controversy p644

R. John Parkes reviews The Deep Hot Biosphere by Thomas Gold

doi:10.1038/44271


Much ado about some thing p645

Ivor Grattan-Guinness reviews The Nothing That Is: A Natural History of Zero by Robert Kaplan

doi:10.1038/44273


Zeroing in on process p645

doi:10.1038/44275


Science in culture p646

Martin Kemp reviews Design by digits

doi:10.1038/44278


Top

Millennium Essay

Revolution in the ocean p647

Victor Hensen realized that in the sea the very small feed the very large.

Victor Smetacek

doi:10.1038/44281


Top

News and Views

Hurricane heat engines p649

A hurricane's path is quite easy to forecast, but its intensity is not. A new model, which takes into account the interaction of the storm and ocean-surface temperature, gives remarkably accurate retrospective simulations.

H. E. Willoughby

doi:10.1038/44287


Neurobiology: Straight from the top p650

Earl K. Miller

doi:10.1038/44291


Quantum physics: Waves, particles and fullerenes p651

Alastair I. M. Rae

doi:10.1038/44294


Ecology: Power behind diversity's throne p653

Shahid Naeem

doi:10.1038/44297


100 and 50 years ago p654

doi:10.1038/44299


Astronomy: Super photon counters p654

John C. Mather

doi:10.1038/44301


Developmental biology: Controlling the cellular brakes p657

Peter Carmeliet

doi:10.1038/44304


Device physics: Memories are made of ... p658

Angus Kingon

doi:10.1038/44307


Immunology: Dual personality of memory T cells p659

Charles R. Mackay

doi:10.1038/44309


Daedalus: Go with the flow p660

David Jones

doi:10.1038/44312


Top

Brief Communications

Familiarity breeds contempt in guppies p661

Male guppy fish increase their reproductive success by mating with unfamiliar females.

J. L. Kelley, J. A. Graves and A. E. Magurran

doi:10.1038/44314


Apoptosis: Searching for FLASH domains p662

Eugene V. Koonin, L. Aravind, Kay Hofmann, Jurg Tschopp and Vishva M. Dixit

doi:10.1038/44317


Reply: Searching for FLASH domains p662

Takaharu Kimura, Yuzuru Imai and Shin Yonehara

doi:10.1038/44320


Materials: Transformation of diamond to graphite p663

Yury G. Gogotsi, Andreas Kailer and Klaus G. Nickel

doi:10.1038/44323


Top

Articles

Thermodynamic control of hurricane intensity p665

Kerry A. Emanuel

doi:10.1038/44326

See also: News and Views by Willoughby


Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts p670

David Lyden, Alison Z. Young, David Zagzag, Wei Yan, William Gerald, Richard O'Reilly, Bernhard L. Bader, Richard O. Hynes, Yuan Zhuang, Katia Manova and Robert Benezra

doi:10.1038/44334

See also: News and Views by Carmeliet


Top

Letters to Nature

Bright rings around sunspots p678

M. P. Rast, P. A. Fox, H. Lin, B. W. Lites, R. W. Meisner and O. R. White

doi:10.1038/44343


Wave–particle duality of C60 molecules p680

Markus Arndt, Olaf Nairz, Julian Vos-Andreae, Claudia Keller, Gerbrand van der Zouw and Anton Zeilinger

doi:10.1038/44348

See also: News and Views by Rae


Lanthanum-substituted bismuth titanate for use in non-volatile memories p682

B. H. Park, B. S. Kang, S. D. Bu, T. W. Noh, J. Lee and W. Jo

doi:10.1038/44352

See also: News and Views by Kingon


Two-dimensional charge transport in self-organized, high-mobility conjugated polymers p685

H. Sirringhaus, P. J. Brown, R. H. Friend, M. M. Nielsen, K. Bechgaard, B. M. W. Langeveld-Voss, A. J. H. Spiering, R. A. J. Janssen, E. W. Meijer, P. Herwig and D. M. de Leeuw

doi:10.1038/44359


Identifying magma–water interaction from the surface features of ash particles p688

Ralf Büttner, Pierfrancesco Dellino and Bernd Zimanowski

doi:10.1038/44364


Determinants of biodiversity regulate compositional stability of communities p691

Mahesh Sankaran and S. J. McNaughton

doi:10.1038/44368

See also: News and Views by Naeem


Symmetry in locomotor central pattern generators and animal gaits p693

Martin Golubitsky, Ian Stewart, Pietro-Luciano Buono and J. J. Collins

doi:10.1038/44416


Probing the human stereoscopic system with reverse correlation p695

Peter Neri, Andrew J. Parker and Colin Blakemore

doi:10.1038/44409


Top-down signal from prefrontal cortex in executive control of memory retrieval p699

Hyoe Tomita, Machiko Ohbayashi, Kiyoshi Nakahara, Isao Hasegawa and Yasushi Miyashita

doi:10.1038/44372

See also: News and Views by Miller


L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons p703

Isabella A. Graef, Paul G. Mermelstein, Kryn Stankunas, Joel R. Neilson, Karl Deisseroth, Richard W. Tsien and Gerald R. Crabtree

doi:10.1038/44378


Two subsets of memory T lymphocytes with distinct homing potentials and effector functions p708

Federica Sallusto, Danielle Lenig, Reinhold Förster, Martin Lipp and Antonio Lanzavecchia

doi:10.1038/44385

See also: News and Views by Mackay


Atomic structure of the GCSF–receptor complex showing a new cytokine–receptor recognition scheme p713

Masaharu Aritomi, Naoki Kunishima, Tomoyuki Okamoto, Ryota Kuroki, Yoshimi Ota and Kosuke Morikawa

doi:10.1038/44394


Structural evidence for dimerization-regulated activation of an integral membrane phospholipase p717

H. J. Snijder, I. Ubarretxena-Belandia, M. Blaauw, K. H. Kalk, H. M. Verheij, M. R. Egmond, N. Dekker and B. W. Dijkstra

doi:10.1038/44890


The reaction cycle of isopenicillin N synthase observed by X-ray diffraction p721

Nicolai I. Burzlaff, Peter J. Rutledge, Ian J. Clifton, Charles M. H. Hensgens, Michael Pickford, Robert M. Adlington, Peter L. Roach and Jack E. Baldwin

doi:10.1038/44400


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New on the Market

Genes amplified, detected, visualized p725

Clean PCR, automatic karyotyping, and other gene-linked matters.

doi:10.1038/44407


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